NF-kappaB and the innate immune response (Q33840493)

29 July 2017

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title

NF-kappaB and the innate immune response (English)

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29 July 2017

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Hatada EN

1

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29 July 2017

Krappmann D

series ordinal

2

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29 July 2017

Scheidereit C

series ordinal

3

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29 July 2017

publication date

1 February 2000

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Current Opinion in Immunology

29 July 2017

published in

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29 July 2017

volume

12

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29 July 2017

issue

1

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29 July 2017

page(s)

52-58

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NF-kappa B: ten years after

29 July 2017

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NF-kappaB to the rescue: RELs, apoptosis and cellular transformation

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NF-kappaB activation: the I kappaB kinase revealed?

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

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Limb and skin abnormalities in mice lacking IKKalpha

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

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Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

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7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

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7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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7 January 2021

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

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7 January 2021

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

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7 January 2021

IKAP is a scaffold protein of the IkappaB kinase complex

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7 January 2021

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

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7 January 2021

Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV

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7 January 2021

Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms

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7 January 2021

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

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7 January 2021

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

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7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

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7 January 2021

Requirement for NF-κB in osteoclast and B-cell development

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7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

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7 January 2021

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

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7 January 2021

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

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7 January 2021

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

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7 January 2021

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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7 January 2021

JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?

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7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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7 January 2021

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

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7 January 2021

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

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7 January 2021

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

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7 January 2021

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

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7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

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7 January 2021

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin

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7 January 2021

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

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7 January 2021

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

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7 January 2021

Substrate targeting in the ubiquitin system

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7 January 2021

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

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7 January 2021

TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

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7 January 2021

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

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7 January 2021

TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses.

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7 January 2021

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

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7 January 2021

10.1016/S0952-7915(99)00050-3

Identifiers

DOI

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29 July 2017

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