O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation (Q33834163)

29 July 2017

title

O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation (English)

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29 July 2017

author

Ludwig Christian Hinske

9

object named as

Ludwig C Hinske

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7

Joerg C Tonn

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29 July 2017

Simone Kreth

1

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29 July 2017

Niklas Thon

2

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29 July 2017

Sabina Eigenbrod

3

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29 July 2017

Juergen Lutz

4

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29 July 2017

Carola Ledderose

5

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29 July 2017

Rupert Egensperger

6

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29 July 2017

Hans A Kretzschmar

8

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29 July 2017

Friedrich W Kreth

10

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29 July 2017

language of work or name

English

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publication date

18 February 2011

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29 July 2017

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volume

6

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29 July 2017

issue

2

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29 July 2017

page(s)

e17156

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Identification of valid endogenous control genes for determining gene expression in human glioma

29 July 2017

cites work

1 reference

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O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients

4 July 2018

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MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas

4 July 2018

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RASSF1A, BLU, NORE1A, PTEN and MGMT expression and promoter methylation in gliomas and glioma cell lines and evidence of deregulated expression of de novo DNMTs.

4 July 2018

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Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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MGMT gene silencing and benefit from temozolomide in glioblastoma

4 July 2018

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4 July 2018

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Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

4 July 2018

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

4 July 2018

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4 July 2018

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MGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patients

21 January 2018

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Novel molecular stereotactic biopsy procedures reveal intratumoral homogeneity of loss of heterozygosity of 1p/19q and TP53 mutations in World Health Organization grade II gliomas.

21 January 2018

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Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors.

21 January 2018

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Nonparametric Estimation from Incomplete Observations

21 January 2018

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Elevated mRNA levels of DNA methyltransferase-1 as an independent prognostic factor in primary nonsmall cell lung cancer.

21 January 2018

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Careful exclusion of non-neoplastic brain components is required for an appropriate evaluation of O6-methylguanine-DNA methyltransferase status in glioma: relationship between immunohistochemistry and methylation analysis

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017156

Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas.

21 January 2018

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Response criteria for phase II studies of supratentorial malignant glioma

29 October 2018

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Detection and interpretation of altered methylation patterns in cancer cells

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21365007

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21365007

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21365007

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0017156

1 reference

29 July 2017

0 references

1 reference

29 July 2017

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