Blood-based biomarkers of Alzheimer's disease: challenging but feasible (Q33824444)

29 July 2017

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title

Blood-based biomarkers of Alzheimer's disease: challenging but feasible (English)

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29 July 2017

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Simon Lovestone

2

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Madhav Thambisetty

series ordinal

1

object named as

Madhav Thambisetty

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29 July 2017

publication date

1 February 2010

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29 July 2017

published in

Biomarkers in Medicine

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29 July 2017

volume

4

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29 July 2017

issue

1

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29 July 2017

page(s)

65-79

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Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

29 July 2017

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease

4 July 2018

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Identification of a 5-protein biomarker molecular signature for predicting Alzheimer's disease

4 July 2018

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Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease

4 July 2018

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4 July 2018

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Gene expression study on peripheral blood identifies progranulin mutations

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

4 July 2018

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4 July 2018

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Plasma biomarkers of Alzheimer's disease

4 July 2018

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Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: a prospective, population-based cohort study

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Inflammatory markers and the risk of Alzheimer disease: the Framingham Study

4 July 2018

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Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium

4 July 2018

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Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkers

4 July 2018

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Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study

4 July 2018

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4 July 2018

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4 July 2018

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Proteome-based plasma biomarkers for Alzheimer's disease

4 July 2018

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Predictors of conversion to dementia of probable Alzheimer type in patients with mild cognitive impairment

4 July 2018

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Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study

4 July 2018

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The Alzheimer's disease neuroimaging initiative

4 July 2018

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Homocysteine and folate as risk factors for dementia and Alzheimer disease

4 July 2018

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Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database

4 July 2018

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High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures

4 July 2018

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Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

4 July 2018

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Mining biomarkers in human sera using proteomic tools

4 July 2018

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Cross‐Linked Fibrin Degradation Products (D‐Dimer), Plasma Cytokines, and Cognitive Decline in Community‐Dwelling Elderly Persons

4 July 2018

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Identification of oxidized plasma proteins in Alzheimer's disease

4 July 2018

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Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

4 July 2018

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Considerations in the evaluation of surrogate endpoints in clinical trials. summary of a National Institutes of Health workshop

4 July 2018

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The dynamic range of protein expression: a challenge for proteomic research

4 July 2018

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Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study

4 July 2018

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Increased plasma apolipoprotein E (apoE) levels in Alzheimer's disease

4 July 2018

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Amyloid beta protein in plasma from patients with sporadic Alzheimer's disease.

4 July 2018

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Identification of fast and slow decliners in Alzheimer disease: a different approach

4 July 2018

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Alzheimer's disease: the amyloid cascade hypothesis

4 July 2018

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Long-term cognitive and functional decline in late onset Alzheimer's disease: therapeutic implications

4 July 2018

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Gene expression as peripheral biomarkers for sporadic Alzheimer's disease

21 January 2018

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Differential RNA expression between schizophrenic patients and controls of the dystrobrevin binding protein 1 and neuregulin 1 genes in immortalized lymphocytes

21 January 2018

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Gene expression changes in peripheral mononuclear cells from schizophrenic patients treated with a combination of antipsychotic with fluvoxamine

21 January 2018

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Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia

21 January 2018

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Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels

21 January 2018

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The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease.

21 January 2018

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Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma

21 January 2018

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21 January 2018

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Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study

21 January 2018

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Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease

21 January 2018

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Blood-brain barrier permeability correlates with medial temporal lobe atrophy but not with amyloid-beta protein transport across the blood-brain barrier in Alzheimer's disease.

21 January 2018

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Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease.

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21 January 2018

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21 January 2018

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Inflammatory proteins in plasma and the risk of dementia: the rotterdam study

21 January 2018

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Altered cytokine and acute phase response protein levels in the blood of children with Downs syndrome: relationship with dementia of Alzheimer's type

21 January 2018

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Is there a relationship between high C-reactive protein (CRP) levels and dementia?

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Plasma C-reactive protein is related to cognitive deterioration and dementia in patients with mild cognitive impairment.

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Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease

21 January 2018

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Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

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Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease

21 January 2018

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'How far' vs 'how fast' in Alzheimer's disease. The question revisited.

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Serum biomarkers for Alzheimer's disease: proteomic discovery

21 January 2018

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Proteomic identification and early validation of complement 1 inhibitor and pigment epithelium-derived factor: Two novel biomarkers of Alzheimer's disease in human plasma.

21 January 2018

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Hydroxyoctadecadienoic acid and oxidatively modified peroxiredoxins in the blood of Alzheimer's disease patients and their potential as biomarkers.

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Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia.

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Plasma homocysteine levels and risk of Alzheimer disease

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In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP.

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29 October 2018

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Coagulation and fibrinolysis markers and risk of dementia. The Dutch Vascular Factors in Dementia Study

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The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone

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Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity

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Identifiers

DOI

10.2217/BMM.09.84

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29 July 2017

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29 July 2017

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