Subcutaneous Nogo receptor removes brain amyloid-beta and improves spatial memory in Alzheimer's transgenic mice (Q33797754)

29 July 2017

title

Subcutaneous Nogo receptor removes brain amyloid-beta and improves spatial memory in Alzheimer's transgenic mice (English)

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29 July 2017

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Stephen M. Strittmatter

object named as

Stephen M Strittmatter

6

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author name string

James H Park

1

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29 July 2017

Gabriel A Widi

2

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29 July 2017

David A Gimbel

3

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29 July 2017

Noam Y Harel

4

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29 July 2017

Daniel H S Lee

5

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29 July 2017

language of work or name

English

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publication date

1 December 2006

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29 July 2017

published in

Journal of Neuroscience

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29 July 2017

volume

26

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29 July 2017

issue

51

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29 July 2017

page(s)

13279-13286

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Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.

29 July 2017

cites work

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Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition

28 July 2018

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Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model

28 July 2018

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Experience-driven plasticity of visual cortex limited by myelin and Nogo receptor

28 July 2018

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Nogo-A interacts with the Nogo-66 receptor through multiple sites to create an isoform-selective subnanomolar agonist

28 July 2018

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Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury

28 July 2018

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Structure of human follicle-stimulating hormone in complex with its receptor

28 July 2018

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Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury

28 July 2018

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RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice

28 July 2018

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Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

28 July 2018

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28 July 2018

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28 July 2018

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Amyloid-beta immunotherapy for Alzheimer's disease: the end of the beginning

28 July 2018

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28 July 2018

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Nogo-66 receptor antagonist peptide promotes axonal regeneration

28 July 2018

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28 July 2018

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Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

28 July 2018

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Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration

28 July 2018

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

28 July 2018

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

28 July 2018

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28 July 2018

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

28 July 2018

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Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

28 July 2018

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Identification and expression analysis of a potential familial Alzheimer disease gene on chromosome 1 related to AD3.

28 July 2018

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Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid

28 July 2018

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Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice.

28 July 2018

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Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury.

30 October 2018

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RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

30 October 2018

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Delayed systemic Nogo-66 receptor antagonist promotes recovery from spinal cord injury.

30 October 2018

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The gamma-secretase inhibitor N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester reduces A beta levels in vivo in plasma and cerebrospinal fluid in young (plaque-free) and aged (plaque-bearing) Tg2576 mice

30 October 2018

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Rho kinase inhibition enhances axonal regeneration in the injured CNS.

30 October 2018

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Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid.

30 October 2018

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Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor

30 October 2018

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Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth

30 October 2018

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model

30 October 2018

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Set back to Alzheimer vaccine studies.

30 October 2018

1 reference

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Metabolic regulation of brain Abeta by neprilysin

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856604

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856604

Amyloid beta vaccination: reduced plaques and improved cognition.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856604

Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856604

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856604

The leucine-rich repeat: a versatile binding motif

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856604

The amyloid deposits in Alzheimer's disease: their nature and pathogenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2856604

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17182778

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.4504-06.2006

1 reference

29 July 2017

1 reference

29 July 2017

1 reference