Synthetic DNA minor groove-binding drugs (Q33784144)

29 July 2017

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title

Synthetic DNA minor groove-binding drugs (English)

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29 July 2017

Reddy BS

1

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29 July 2017

Sondhi SM

series ordinal

2

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29 July 2017

Lown JW

series ordinal

3

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29 July 2017

publication date

1 October 1999

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Pharmacology & Therapeutics

29 July 2017

published in

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29 July 2017

volume

84

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29 July 2017

issue

1

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29 July 2017

page(s)

1-111

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DNA sequence preferences of several AT-selective minor groove binding ligands

29 July 2017

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Synthesis and biochemical evaluation of the CBI-PDE-I-dimer, a benzannelated analog of (+)-CC-1065 that also produces delayed toxicity in mice

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Nonintercalative DNA-binding antitumour compounds

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Subcellular distribution of a nitroxide spin-labeled netropsin-acridine hybrid in living KB cells: Electron Spin Resonance Study

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Drug-DNA sequence-dependent interactions analysed by electric linear dichroism

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The different binding modes of Hoechst 33258 to DNA studied by electirc linear dichroism

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Mode of DNA binding of bis-benzimidazoles and related structures studied by electric linear dichroism

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7 January 2021

The binding mode of drugs to the TAR RNA of HIV-1 studied by electric linear dichroism

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7 January 2021

Sequence-selective binding to DNA of bis(amidinophenoxy)alkanes related to propamidine and pentamidine

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Inhibitory activity of diarylamidine derivatives on murine leukemia L1210 cell growth

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Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogues of pyrrolo[1,4][2,1-c]benzodiazepines

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7 January 2021

Berenil recognizes and changes the characteristics of adenine and thymine polynucleotide structures

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7 January 2021

Fluorescence lifetime distributions of DNA-4',6-diamidino-2-phenylindole complex

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7 January 2021

The fluorescence properties of a DNA probe. 4'-6-Diamidino-2-phenylindole (DAPI)

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7 January 2021

Pyrrolo[1,4]benzodiazepine antitumor antibiotics: evidence for two forms of tomaymycin bound to DNA

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7 January 2021

Molecular recognition between ligands and nucleic acids: novel pyridine- and benzoxazole-containing agents related to Hoechst 33258 that exhibit altered DNA sequence specificity deduced from footprinting analysis and spectroscopic studies

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7 January 2021

Effects of analogs of the DNA minor groove binder Hoechst 33258 on topoisomerase II and I mediated activities

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7 January 2021

Distamycin A and tallimustine inhibit TBP binding and basal in vitro transcription.

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7 January 2021

Adozelesin, a potent new alkylating agent: cell-killing kinetics and cell-cycle effects

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7 January 2021

Stoichiometry and structure of complexes of DNA oligomers with microgonotropens and distamycin by 1H NMR spectroscopy and molecular modeling

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7 January 2021

Catalysis of the CC-1065 and duocarmycin DNA alkylation reaction: DNA binding induced conformational change in the agent results in activation

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7 January 2021

CC-1065/duocarmycin and bleomycin A2 hybrid agents: lack of enhancement of DNA alkylation by attachment to noncomplementary DNA binding subunits

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7 January 2021

CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents

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7 January 2021

Demonstration of a pronounced effect of noncovalent binding selectivity on the (+)-CC-1065 DNA alkylation and identification of the pharmacophore of the alkylation subunit

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7 January 2021

Evaluation of functional analogs of CC-1065 and the duocarmycins incorporating the cross-linking 9a-chloromethyl-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-on e (C2BI) alkylation subunit.

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7 January 2021

Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity

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7 January 2021

1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation

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7 January 2021

Demonstration and definition of the noncovalent binding selectivity of agents related to CC-1065 by an affinity cleavage agent: noncovalent binding coincidental with alkylation

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7 January 2021

Sequence-directed single strand cleavage of DNA by a netropsin-flavin hybrid molecule

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7 January 2021

Characterization of a unique tomaymycin-d(CICGAATTCICG)2 adduct containing two drug molecules per duplex by NMR, fluorescence, and molecular modeling studies

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7 January 2021

Existence of an extended series of antitumor compounds which bind to deoxyribonucleic acid by nonintercalative means

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7 January 2021

DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin

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7 January 2021

Crystal structure of a berenil-d(CGCAAATTTGCG) complex. An example of drug-DNA recognition based on sequence-dependent structural features

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7 January 2021

Minor groove binding ligands alter the rotational positioning of DNA fragments on nucleosome core particles

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7 January 2021

Specific interactions of 4'-6-diamidino-2-phenylindole with nucleosome

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7 January 2021

Influence of 4?-6-diamidino-2-phenylindole on the secondary structure and template activities of DNA and polydeoxynucleotides

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7 January 2021

The c-myc promoter binding protein (MBP-1) and TBP bind simultaneously in the minor groove of the c-myc P2 promoter

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7 January 2021

One- and two-dimensional 1H NMR, fluorescence, and molecular modeling studies on the tomaymycin-d(ATGCAT)2 adduct. Evidence for two covalent adducts with opposite orientations and stereochemistries at the covalent linkage site

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7 January 2021

DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.

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7 January 2021

DNA crosslinking, sister chromatid exchange and cytotoxicity of N-2-chloroethylnitrosoureas tethered to minor groove binding peptides.

1 reference

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7 January 2021

Two-dimensional NMR studies of d(GGTTAATGCGGT).d(ACCGCATTAACC) complexed with the minor groove binding drug SN-6999

1 reference

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7 January 2021

Design of distamicin analogues to probe the physical origin of the antiparallel side by side oligopeptide binding motif in DNA minor groove recognition

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7 January 2021

Use of DAPI cytofluorometric analysis of cellular DNA content to differentiate Spitz nevus from malignant melanoma

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7 January 2021

Effects of minor groove binding drugs on the interaction of TATA box binding protein and TFIIA with DNA.

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7 January 2021

Targeting E2F1-DNA complexes with microgonotropen DNA binding agents

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7 January 2021

New sulfonated distamycin A derivatives with bFGF complexing activity

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7 January 2021

Distamycin analogues with improved sequence-specific DNA binding activities.

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7 January 2021

Novel sulfonated and phosphonated analogs of distamycin which inhibit the replication of HIV.

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7 January 2021

Isohelicity and phasing in drug--DNA sequence recognition: crystal structure of a tris(benzimidazole)--oligonucleotide complex

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7 January 2021

Designer DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d(CGCGAATTCGCG)2

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7 January 2021

Structure of a bis-amidinium derivative of hoechst 33258 complexed to dodecanucleotide d(CGCGAATTCGCG)2: the role of hydrogen bonding in minor groove drug-DNA recognition

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7 January 2021

Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethylxanthenone acetic acid

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7 January 2021

Use of electric linear dichroism and competition experiments with intercalating drugs to investigate the mode of binding of Hoechst 33258, berenil and DAPI to GC sequences

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7 January 2021

Electric linear dichroism as a new tool to study sequence preference in drug binding to DNA.

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7 January 2021

Mechanisms of chromosome banding. VIII. Hoechst 33258-DNA interaction

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7 January 2021

THE EFFECT OF GLUCOSE PRETREATMENT ON THE CARCINOSTATIC AND TOXIC ACTIVITIES OF SOME ALKYLATING AGENTS

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7 January 2021

Interaction of minor-groove-binding diamidine ligands with an asymmetric DNA duplex. NMR and molecular modelling studies

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7 January 2021

Structure and DNA binding activity of analogs of 1,5-bis(4-amidinophenoxy)pentane (pentamidine)

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7 January 2021

Evaluation of the antineoplastic activity of Adozelesin alone and in combination with 5-aza-2-deoxycytidine and cytosine arabinoside on DLD-1 human colon carcinoma cells

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7 January 2021

Anti-insulin-like growth factor-I activity of a novel polysulphonated distamycin A derivative in human lung cancer cell lines

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7 January 2021

DNA ligands as radioprotectors: molecular studies with Hoechst 33342 and Hoechst 33258.

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7 January 2021

Potential antitumor agents. 31. Quantitative structure-activity relationships for the antileukemic bis(guanylhydrazones)

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7 January 2021

Potential antitumor agents. 29. Quantitative structure-activity relationships for the antileukemic bisquaternary ammonium heterocycles

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7 January 2021

Design of sequence-specific DNA-binding molecules

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7 January 2021

Synthesis and antiviral activity of three pyrazole analogues of distamycin A.

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7 January 2021

Pentamidine Congeners. 3. Crystal Structure and Molecular Modeling Studies of trans-1,4-Bis( 4-amidinphenoxy)-2-butene

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7 January 2021

Effects of Hoechst 33258 on different cell cycle events. I. Inhibition of synthetic activities in bone-marrow cells of the mole rat Bandicota bengalensis

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7 January 2021

Interaction of Hoechst 33258 with a DNA triple helix

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7 January 2021

Berenil complexation with a nucleic acid triple helix

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7 January 2021

High-performance liquid chromatographic method for measurement of pentamidine in plasma and its application in an immunosuppressed patient with renal dysfunction

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7 January 2021

Comparison of cell-cycle phase perturbations induced by the DNA-minor-groove alkylator tallimustine and by melphalan in the SW626 cell line

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7 January 2021

Crystal structure of a pentamidine-oligonucleotide complex: implications for DNA-binding properties

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7 January 2021

Interaction of Hoechst 33258 with the minor groove of the A + T‐rich DNA duplex d(GGTAATTACC)2 studied in solution by NMR spectroscopy

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7 January 2021

Once-a-month administration of intravenous pentamidine to patients infected with human immunodeficiency virus as prophylaxis for Pneumocystis carinii pneumonia

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7 January 2021

Binding of 4',6-diamidino-2-phenylindole (DAPI) to AT regions of DNA: evidence for an allosteric conformational change

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7 January 2021

An NMR study of [d(CGCGAATTCGCG)]2 containing an interstrand cross-link derived from a distamycin-pyrrole conjugate

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7 January 2021

DNA binding properties of a new class of linked anthramycin analogs

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7 January 2021

Dynamics and binding mode of Hoechst 33258 to d(GTGGAATTCCAC)2 in the 1:1 solution complex as determined by two-dimensional 1H NMR.

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics

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7 January 2021

Microbial mutagenic effects of the DNA minor groove binder pibenzimol (Hoechst 33258) and a series of mustard analogues

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7 January 2021

The sites and relative frequencies of secondary constrictions in human somatic chromosomes

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7 January 2021

Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II

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7 January 2021

The effect of AT and GC sequence specific minor groove-binding agents on restriction endonuclease activity

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7 January 2021

Different effects of nonintercalative antitumor drugs on DNA triple helix stability: SN-18071 promotes triple helix formation

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7 January 2021

Phase I trial of Adozelesin using the treatment schedule of daily x5 every 3 weeks

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Footprinting studies on the sequence-selective binding of pentamidine to DNA

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Structure and drug interactions of parallel-stranded DNA studied by infrared spectroscopy and fluorescence

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7 January 2021

Minor groove binding of SN6999 to an alkylated DNA: molecular structure of d(CGC[e6G]AATTCGCG)-SN6999 complex

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Effects of different DNA polymerases in ligation-mediated PCR: enhanced genomic sequencing and in vivo footprinting

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Structural and dynamic characterization of the heterodimeric and homodimeric complexes of distamycin and 1-methylimidazole-2-carboxamide-netropsin bound to the minor groove of DNA.

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7 January 2021

Design of a G.C-specific DNA minor groove-binding peptide.

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7 January 2021

Estimation of the haematological toxicity of minor groove alkylators using tests on human cord blood cells

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The reaction of anthramycin with DNA. 3. Properties of the complex

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7 January 2021

Synthesis, characterization, and DNA modification induced by a novel Pt-berenil compound with cytotoxic activity

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7 January 2021

Isohelical analysis of DNA groove-binding drugs

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Refinement of netropsin bound to DNA: bias and feedback in electron density map interpretation

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Structure of a dicationic monoimidazole lexitropsin bound to DNA

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7 January 2021

Theoretical study on binding of Hoechst 33258 with oligonucleotides

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7 January 2021

Selective binding to polynucleotides of the hybrid intercalating groove binder bis(pyrrolecarboxamide)-oxazolopyridocarbazole: a molecular modeling study

1 reference

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7 January 2021

DNA-directed alkylating agents. 6. Synthesis and antitumor activity of DNA minor groove-targeted aniline mustard analogues of pibenzimol (Hoechst 33258)

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7 January 2021

Enhanced DNA alkylation activities of Hoechst 33258 analogues designed for bioreductive activation

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7 January 2021

Administration of aerosolized pentamidine to HIV-infected infants

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7 January 2021

CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DC 102, a new glycosidic pyrrolo(1,4)benzodiazepine antibiotic produced by Streptomyces sp

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7 January 2021

A fluorescence study of the binding of Hoechst 33258 and DAPI to halogenated DNAs

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Molecular recognition of B-DNA by Hoechst 33258.

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7 January 2021

DNA sequence specificity of the pyrrolo[1,4]benzodiazepine antitumor antibiotics. Methidiumpropyl-EDTA-iron(II) footprinting analysis of DNA binding sites for anthramycin and related drugs

1 reference

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7 January 2021

Comparison of U-73,975 and cisplatin cytotoxicity in fresh cervical and ovarian carcinoma specimens with the ATP-chemosensitivity assay

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7 January 2021

In vitro evaluation of the novel chemotherapeutic agents U-73,975, U-77,779, and U-80,244 in gynecologic cancer cell lines

1 reference

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7 January 2021

Abbeymycin, a new anthramycin-type antibiotic produced by a streptomycete

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Therapeutic efficacy of the cyclopropylpyrroloindole, carzelesin, against xenografts derived from adult and childhood solid tumors

1 reference

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7 January 2021

1H-NMR studies on d(GCTTAAGC)2 and its complex with berenil

1 reference

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7 January 2021

Pyrrolo(1,4)benzodiazepine antitumor antibiotics. Comparative aspects of anthramycin, tomaymycin and sibiromycin

1 reference

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7 January 2021

Proposed structure of the anthramycin–DNA adduct

1 reference

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7 January 2021

Pyrrolo(1,4)benzodiazepine antitumor antibiotics In vitro interaction of anthramycin, sibiromycin and tomaymycin with DNA using specifically radiolabelled molecules

1 reference

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7 January 2021

Proposed structures of the pyrrolo(1,4)benzodiazepine antibiotic-deoxyribonucleic acid adducts

1 reference

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7 January 2021

Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity

1 reference

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7 January 2021

Molecular basis for sequence-specific DNA alkylation by CC-1065

1 reference

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7 January 2021

Sibanomicin, a new pyrrolo[1,4]benzodiazepine antitumor antibiotic produced by a Micromonospora sp

1 reference

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7 January 2021

Binding of DAPI analogue 2,5-bis(4-amidinophenyl)furan to DNA.

1 reference

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7 January 2021

AT selectivity and DNA minor groove binding: modelling, NMR and structural studies of the interactions of propamidine and pentamidine with d(CGCGAATTCGCG)2.

1 reference

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7 January 2021

NMR and molecular modeling studies of the interaction of berenil and pentamidine with d(CGCAAATTTGCG)2.

1 reference

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7 January 2021

Photofootprinting of drug-binding sites on DNA using diazo- and azido-9-aminoacridine derivatives

1 reference

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7 January 2021

Characterization of the minor groove environment in a drug-DNA complex: bisbenzimide bound to the poly[d(AT)].poly[d(AT)]duplex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Interaction of Hoechst 33258 with repeating synthetic DNA polymers and natural DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Time-dose-response of Trypanosoma brucei brucei to diminazene aceturate (Berenil) and in vitro simulation of drug-concentration-time profiles in cattle plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DAPI: a DNA-specific fluorescent probe

1 reference

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7 January 2021

Buoyant density of DNA-Hoechst 33258 (bisbenzimide) complexes in CsCl gradients: Hoechst 33258 binds to single AT base pairs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Limitation of DNA-4',6-diamidine-2-phenylindole assay in the presence of an excess of tRNA

1 reference

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7 January 2021

Binding of Net-Fla, a netropsin-flavin hybrid molecule, to DNA: molecular mechanics and dynamics studies in vacuo and in water solution

1 reference

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7 January 2021

Z → B transition in poly[d(G-m5C)2] induced by interaction with 4′,6-diamidino-2-phenylindole

1 reference

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7 January 2021

Correlation of DNA sequence specificity of anthramycin and tomaymycin with reaction kinetics and bending of DNA

1 reference

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7 January 2021

Chicamycin, a new antitumor antibiotic. II. Structure determination of chicamycins A and B

1 reference

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7 January 2021

Anthramycin, a new type of DNA-inhibiting antibiotic: reaction with DNA and effect on nucleic acid synthesis in mouse leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-A-A-C-G-T-T-G-G and a molecular explanation of specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Defining GC-specificity in the minor groove: side-by-side binding of the di-imidazole lexitropsin to C-A-T-G-G-C-C-A-T-G

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Effect of cationic drugs on suprahelical organization of DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The reduction of intracellular polyamines by sequential inhibition of the synthesis of decarboxylated S-adenosylmethionine: effects on rat leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The origin of the DNA induced circular dichroism of CC-1065 and analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DNA sequence recognition by the antitumor antibiotic CC-1065 and analogs of CC-1065

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Two-dimensional NMR studies on the anthramycin-d(ATGCAT)2 adduct

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Characterization of interaction between DNA and 4',6-diamidino-2-phenylindole by optical spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Sequence Specific Molecular Recognition and Binding by a GC Recognizing Hoechst 33258 Analogue to the Decadeoxyribonucleotide d-[CATGGCCATG]2: Structural and Dynamic Aspects Deduced from High Field1H-NMR Studies

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Structure and dynamics of ligand-template interactions of topoisomerase inhibitory analogs of Hoechst 33258: high field 1H-NMR and restrained molecular mechanics studies

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Mazethramycin, a new member of anthramycin group antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Interaction of berenil with the EcoRI dodecamer d(CGCGAATTCGCG)2 in solution studied by NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The structure of DAPI bound to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Interaction of berenil with the tyrT DNA sequence studied by footprinting and molecular modelling. Implications for the design of sequence-specific DNA recognition agents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Binding of non-intercalating antibiotics to B-DNA: a theoretical study taking into account nucleic acid flexibility

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Nucleotide preferences for DNA interstrand cross-linking induced by the cyclopropylpyrroloindole analogue U-77,779.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DNA interstrand cross-links induced by the cyclopropylpyrroloindole antitumor agent bizelesin are reversible upon exposure to alkali

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Mapping of DNA alkylation sites induced by adozelesin and bizelesin in human cells by ligation-mediated polymerase chain reaction.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

GC base sequence recognition by oligo(imidazolecarboxamide) and C-terminus-modified analogues of distamycin deduced from circular dichroism, proton nuclear magnetic resonance, and methidiumpropylethylenediaminetetraacetate-iron(II) footprinting stud

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

GC sequence specific recognition by an N-formamido, C-terminus-modified and imidazole-containing analogue of netropsin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

In vitro photoinduced cytotoxicity and DNA binding properties of psoralen and coumarin conjugates of netropsin analogues: DNA sequence-directed alkylation and cross-link formation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The Structure of Anthramycin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Isolation and Characterization of Anthramycin, a New Antitumor Antibiotic

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

NMR studies of the complex between the decadeoxynucleotide d-(GCATTAATGC)2 and a minor-groove-binding drug

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Application of 13C(omega 1)-half-filtered [1H,1H]-NOESY for studies of a complex formed between DNA and a 13C-labeled minor-groove-binding drug.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Inhibition of enzymes of polyamine back-conversion by pentamidine and berenil

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Optical Studies of the interaction of 4'-6'-diamidino-2-phenylindole with DNA and metaphase chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Binding characteristics of Hoechst 33258 with calf thymus DNA, poly[d(A-T)] and d(CCGGAATTCCGG): multiple stoichiometries and determination of tight binding with a wide spectrum of site affinities

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Binding of Hoechst 33258 and 4',6-diamidino-2-phenylindole to self-complementary decadeoxynucleotides with modified exocyclic base substituents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DNA recognition by lexitropsins, minor groove binding agents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Molecular mechanism of binding of pyrrolo(1,4)benzodiazepine antitumour agents to deoxyribonucleic acid--anthramycin and tomaymycin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Pentamidine-Induced Hyperglycemia and Ketosis in Acquired Immunodeficiency Syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Interaction of the nonintercalative antitumour drugs SN-6999 and SN-18071 with DNA: influence of ligand structure on the binding specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Rapid and efficient hybridization-triggered crosslinking within a DNA duplex by an oligodeoxyribonucleotide bearing a conjugated cyclopropapyrroloindole

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

CC-1065 (NSC 298223), a potent new antitumor agent improved production and isolation, characterization and antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Comparative studies of UV-induced DNA cleavage by analogues of iodoHoechst 33258.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Fluorospectrometric studies on neothramycin and its reaction with DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Asymmetric decondensation of the L cell heterochromatin by Hoechst 33258

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Novel Acridine-Triazenes as Prototype Combilexins: Synthesis, DNA Binding, and Biological Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Preliminary toxicity studies with the DNA-binding antibiotic, CC-1065

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Equilibrium binding of Hoechst 33258 and Hoechst 33342 fluorochromes with rat colorectal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Effect of minor groove binding drugs on mammalian topoisomerase I activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Effects of minor groove binding drugs on camptothecin-induced DNA lesions in L1210 nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Fluorometric determination of DNA in epidermis and cultured fibroblasts, using 4'-6-diamidino-2-phenylindole (DAPI)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Interaction of 4′-6-diamidino-2-phenylindole to nucleic acids, and its implication to their template activity in RNA-polymerase reaction of E. coli bacteria and of friend-virus infected mouse spleen

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Salt effects on ligand-DNA binding. Minor groove binding antibiotics.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Total synthesis and biological properties of novel antineoplastic (chloromethyl)furanoindolines: an asymmetric hydroboration mediated synthesis of the alkylation subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Determination of receptor-bound drug conformations by QSAR using flexible fitting to derive a molecular similarity index

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DNA structural features responsible for sequence-dependent binding geometries of Hoechst 33258.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Evaluation of the electrophilicity of DNA-binding pyrrolo[2,1-c][1,4]benzodiazepines by HPLC

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Comparison of a DSB-120 DNA interstrand cross-linked adduct with the corresponding bis-tomaymycin adduct: an example of a successful template-directed approach to drug design based upon the monoalkylating compound tomaymycin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Antileishmanial activity of berenil and methylglyoxal bis (guanylhydrazone) and its correlation with S-adenosylmethionine decarboxylase and polyamines

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

In vivo footprinting of a muscle specific enhancer by ligation mediated PCR.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Sequence specificity of 125I-labelled Hoechst 33258 damage in six closely related DNA sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Sequence specificity of 125I-labelled Hoechst 33258 in intact human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

In vitro evaluation of a novel chemotherapeutic agent, Adozelesin, in gynecologic-cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Spectrum of cell-cycle kinetics of alkylating agent adolezesin in gynecological cancer cell lines: correlation with drug-induced cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Comparison of ethidium bromide and 4'6-diamidino-2-phenylindole as quantitative fluorescent stains for DNA in agarose gels

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Design of sequence-specific DNA binding ligands that use a two-stranded peptide motif for DNA sequence recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Analysing DNA complexes by circular and linear dichroism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

High-sensitivity linear dichroism as a tool for equilibrium analysis in biochemistry- stability constant of DNA-ethidiumbromide complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Sequence-Dependent Drug Binding to the Minor Groove of DNA: Crystal Structure of the DNA Dodecamer d(CGCAAATTTGCG)2 Complexed with Propamidine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Crystal structure of d(CGCGAATTCGCG) complexed with propamidine, a short-chain homologue of the drug pentamidine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Crystal structure of gamma-oxapentamidine complexed with d(CGCGAATTCGCG)2. The effects of drug structural change on DNA minor-groove recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DAPI-pUC8 complex: a tool to investigate biological effects of nucleic acid-drug interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Minor-groove recognition of the self-complementary duplex d(CGCGAATTCGCG)2 by Hoechst 33258: a high-field NMR study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Molecular design of DNA-directed ligands with specific interactions: solution NMR studies of the interaction of a m-hydroxy analogue of Hoechst 33258 with d(CGCGAATTCGCG)2.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Predictability of designing specific binding interactions for DNA minor groove ligands from NMR spectroscopy and molecular modeling: a copper(II)-activated DNA cleaver based on Hoechst 33258.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

A model for the sequence-dependent DNA binding of 4',6-diamidino-2-phenylindole (DAPI).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Differential effects of distamycin analogues on amplification of human gene sequences by polymerase-chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The crystal structure of the DNA-binding drug berenil: molecular modelling studies of berenil-DNA complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Fatal pancreatitis as a complication of therapy for HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Binding of Pt-pentamidine to nucleosomal DNA. Studies of the antiproliferative activity of the drug against human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Pyrrol[1,4]benzodiazepine antibiotics. Proposed structures and characteristics of the in vitro deoxyribonucleic acid adducts of anthramycin, tomaymycin, sibiromycin, and neothramycins A and B.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Biological profile of FCE 24517, a novel benzoyl mustard analogue of distamycin A

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Genomic sequencing and methylation analysis by ligation mediated PCR.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Comparison of sequence preference of tomaymycin- and anthramycin-DNA bonding by exonuclease III and lambda exonuclease digestion and UvrABC nuclease incision analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Ligand-induced formation of nucleic acid triple helices

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Berenil binding to higher ordered nucleic acid structures: complexation with a DNA and RNA triple helix

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Berenil [1,3-Bis(4'-amidinophenyl)triazene] Binding to DNA Duplexes and to a RNA Duplex: Evidence for Both Intercalative and Minor Groove Binding Properties

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Effects of Hoechst 33258 on human leukocytes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Binding of Hoechst 33258 to the minor groove of B-DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Antitumor combilexin. A thiazole-containing analogue of netropsin linked to an acridine chromophore

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Berenil acts as a poison of eukaryotic topoisomerase II

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Comparison of binding sites in DNA for berenil, netropsin and distamycin. A footprinting study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Assignment of DNA binding sites for 4',6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Two-dimensional 1H and 31P NMR spectra and restrained molecular dynamics structure of a covalent CPI-CDPI2-oligodeoxyribonucleotide decamer complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Tallimustine in advanced previously untreated colorectal cancer, a phase II study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Inhibition of bacteriophage T7 RNA polymerase in vitro transcription by DNA-binding pyrrolo[2,1-c][1,4]benzodiazepines

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Low-temperature crystallographic analyses of the binding of Hoechst 33258 to the double-helical DNA dodecamer C-G-C-G-A-A-T-T-C-G-C-G

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Molecular recognition between ligands and nucleic acids: DNA binding characteristics of analogs of Hoechst 33258 designed to exhibit altered base and sequence recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DNA interaction of the imidazole-containing lexitropsin ImPy: titration viscometric study in comparison to netropsin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Deformyldistamycin-DNA interaction; DNA conformational changes as revealed by titration rotational viscometry

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Conformations of complexes between pyrrolo[1,4]benzodiazepines and DNA segments

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Reaction of the antitumor antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Effects of DAPI on human leukocytes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Properties of a purified nuclear topoisomerase from L1210 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Increased sensitivity of the Walker tumour towards aromatic nitrogen mustards carrying basic side chains following glucose pretreatment

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The width of the minor groove affects the binding of the bisquaternary heterocycle SN-6999 to duplex DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Long-range interactions between DNA-bound ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Quantum chemical studies employing an ab initio combination approach on the binding of the bis-benzimidazole Hoechst 33258 to the minor groove of DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

A thermodynamic and spectroscopic study on the binding of berenil to poly d(AT) and to poly (dA) x poly (dT)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Thermodynamic and spectroscopic characterization of the berenil and pentamidine complexes with the dodecanucleotide d(CGCGATATCGCG)2.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Interstrand cross-linking by bizelesin produces a Watson-Crick to Hoogsteen base-pairing transition region in d(CGTAATTACG)2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Sequence-specific interaction of Hoescht 33258 with the minor grooVe of an adenine-tract DNA duplex studied in solution by1H NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Phase I study of the novel distamycin derivative tallimustine (FCE 24517)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Phase I study of adozelesin (U-73,975) in patients with solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Prothracarcin, a novel antitumor antibiotic

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Competition between netropsin and restriction nuclease EcoRI for DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The osmotic sensitivity of netropsin analogue binding to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Synthesis and sequence-specific DNA binding of a topoisomerase inhibitory analog of Hoechst 33258 designed for altered base and sequence recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The binding of berenil to Escherichia coli ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Cellular pharmacology of novel C8-linked anthramycin-based sequence-selective DNA minor groove cross-linking agents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Synergistic and additive combinations of several antitumor drugs and other agents with the potent alkylating agent adozelesin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

A role of DNA topoisomerases in the active dissociation of DNA minor groove-ligand complexes. A flow cytometric study of inhibitor effects

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The binding modes of a rationally designed photoactivated DNA nuclease determined by NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Sequence-dependent effects in drug-DNA interaction: the crystal structure of Hoechst 33258 bound to the d(CGCAAATTTGCG)2 duplex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Crystal and solution structures of d(CGC[e6G]AATTCGCG)-drug complexes reveal conformational polymorphism of O6-ethyl-guanine:cytosine base pair

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Multiple binding modes for Hoechst 33258 to DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Binding of Hoechst 33258 to chromatin in situ

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Studies on the ability of minor groove binders to induce supercoiling in DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Inhibition of the Moloney murine leukemia virus cycle at a post reverse transcriptional step by the netropsin-intercalating hybrid molecule netropsin-oxazolopyridocarbazole

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Alkylation of guanine and cytosine in DNA by bizelesin. Evidence for a covalent immobilization leading to a proximity-driven alkylation of normally unreactive bases by a (+)-CC-1065 cross-linking compound

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Hairpin polyamides that use parallel and antiparallel side-by-side peptide motifs in binding to DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Evaluation of DNA binding characteristics of some CC-1065 analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Combination of the new minor groove alkylator tallimustine and melphalan

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Neothramycins A and B, new antitumor antibiotics.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DAPI (4',6-diamidino-2-phenylindole) binds differently to DNA and RNA: minor-groove binding at AT sites and intercalation at AU sites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Determination of the Structural Role of the Internal Guanine-Cytosine Base Pair in Recognition of a Seven-Base-Pair Sequence Cross-Linked by Bizelesin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

O-Debenzylation of a Pyrrolo[2,1-c][1,4]benzodiazepine in the Presence of a Carbinolamine Functionality: Synthesis of DC-81

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Localization of polyphosphates in Saccharomyces fragilis, as revealed by 4',6-diamidino-2-phenylindole fluorescence

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Studies on tomaymycin. II. Total syntheses of the antitumor antibiotics, E-and Z-tomaymycins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Studies on tomaymycin. III. Synthesis and antitumor activity of tomaymycin analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Evidence for DAPI intercalation in CG sites of DNA oligomer [d(CGACGTCG)]2: a 1H NMR study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Simultaneous and different binding mechanisms of 4',6-diamidino-2-phenylindole to DNA hexamer (d(CGATCG))2. A 1H NMR study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Effects of minor and major groove-binding drugs and intercalators on the DNA association of minor groove-binding proteins RecA and deoxyribonuclease I detected by flow linear dichroism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The mutagenic properties of DNA minor-groove binding ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Some properties of new DNA-specific bisbenzimidazole fluorochromes without a piperazine ring

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Myelotoxic effects of the bifunctional alkylating agent bizelesin on human, canine and murine myeloid progenitor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Binding affinities of synthetic peptides, pyridine-2-carboxamidonetropsin and 1-methylimidazole-2-carboxamidonetropsin, that form 2:1 complexes in the minor groove of double-helical DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Studies on 1,3-diaryltriazene analogues of berenil: molecules with potential GC base-pair selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Template-directed design of a DNA-DNA cross-linker based upon a bis-tomaymycin-duplex adduct

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

CC-1065 functional analogues possessing different electron-withdrawing substituents and leaving groups: synthesis, kinetics, and sequence specificity of reaction with DNA and biological evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Effects of bifunctional netropsin-related minor groove-binding ligands on mammalian type I DNA topoisomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

In vitro and in vivo DNA bonding by the CC-1065 analog U-73975

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Exploiting tumor hypoxia through bioreductive release of diffusible cytotoxins: the cobalt(III)-nitrogen mustard complex SN 24771

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DNA sequence dependent binding modes of 4',6-diamidino-2-phenylindole (DAPI).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The search for structure-specific nucleic acid-interactive drugs: Effects of compound structure on RNA versus DNA interaction strength

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Interactions of DNA binding ligands with PNA-DNA hybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Transcriptional regulation of differentiation, selective toxicity and ATGCAAAT binding of bisbenzimidazole derivatives in human melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Variability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Sequence specificity of alkylation for a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size: evidence for increased cytotoxicity with enhanced sequence specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Enhancement and alteration of bleomycin-catalyzed site-specific DNA cleavage by distamycin A and some minor groove binders

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Studies on cooperative binding of an extended distamycin A analogue in the minor groove of DNA by NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Structural analysis of d(GCAATTGC)2 and its complex with berenil by nuclear magnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Opposite effect between intercalator and minor groove binding drug on the higher order structure of DNA as is visualized by fluorescence microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Aerosolized pentamidine. Approved for HIV-infected individuals at high risk for Pneumocystis carinii pneumonia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Theoretical studies of the selective binding to DNA of two non-intercalating ligands: netropsin and SN 18071

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

The solvation contribution to the binding energy of DNA with non-intercalating antibiotics.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

Resistance of CHO cells expressing P-glycoprotein to cyclopropylpyrroloindole (CPI) alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900021-2

7 January 2021

10.1016/S0163-7258(99)00021-2

Identifiers

DOI

1 reference

29 July 2017

1 reference