Dendritic cells program non-immunogenic prostate-specific T cell responses beginning at early stages of prostate tumorigenesis. (Q33756652)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17221844%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Dendritic cells program non-immunogenic prostate-specific T cell responses beginning at early stages of prostate tumorigenesis (English)

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24 December 2019

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4

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24 December 2019

author name string

Marianne A Mihalyo

1

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24 December 2019

Adam T Hagymasi

2

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24 December 2019

Aaron M Slaiby

3

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24 December 2019

Adam J Adler

5

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24 December 2019

publication date

1 April 2007

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24 December 2019

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24 December 2019

volume

67

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24 December 2019

issue

5

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24 December 2019

page(s)

536-546

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Mechanisms of T cell tolerance and suppression in cancer mediated by tumor-associated antigens and hormones

24 December 2019

cites work

1 reference

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Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

21 June 2018

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21 June 2018

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Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen

21 June 2018

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Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

21 June 2018

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21 June 2018

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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 June 2018

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21 June 2018

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Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-alpha and IFN-gamma expression potentials

21 June 2018

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CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses

21 June 2018

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Does the immune system see tumors as foreign or self?

21 June 2018

1 reference

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The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens

21 June 2018

1 reference

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Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node

21 June 2018

1 reference

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Effector CD4 cells are tolerized upon exposure to parenchymal self-antigen

21 June 2018

1 reference

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In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

21 June 2018

1 reference

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Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

21 June 2018

1 reference

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846359

Certified professionals: CD4(+)CD25(+) suppressor T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846359

Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846359

Regulatory T cells: key controllers of immunologic self-tolerance

21 June 2018

1 reference

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Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

21 June 2018

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Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

21 June 2018

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CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2846359

Induction of antigen-specific T cell anergy: An early event in the course of tumor progression

21 June 2018

1 reference

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Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells

21 June 2018

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An evaluation of the potential to use tumor-associated antigens as targets for antitumor T cell therapy using transgenic mice expressing a retroviral tumor antigen in normal lymphoid tissues

21 June 2018

1 reference

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Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor

21 June 2018

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Prostate cancer in a transgenic mouse

21 June 2018

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Toll-dependent control mechanisms of CD4 T cell activation

21 June 2018

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Depletion of CD25(+) CD4(+) T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon alpha-induced, CD8(+) T-cell-dependent immune defense of B16 melanoma.

30 October 2018

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Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade.

30 October 2018

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CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism

30 October 2018

1 reference

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30 October 2018

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12 December 2020

Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells

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12 December 2020

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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12 December 2020

Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion

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12 December 2020

Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunity

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12 December 2020

Pathologic progression of autochthonous prostate cancer in the TRAMP model

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12 December 2020

Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model

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12 December 2020

Therapeutic cancer vaccines

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12 December 2020

In vivo CD4+ T cell tolerance induction versus priming is independent of the rate and number of cell divisions

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12 December 2020

Eradication of established tumors by CD8+ T cell adoptive immunotherapy

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12 December 2020

Peripheral T cell tolerance as a tumor escape mechanism: deletion of CD4+ T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma

1 reference

12 December 2020

Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells

1 reference

12 December 2020

Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction

1 reference

12 December 2020

Identifiers

DOI

10.1002/PROS.20549

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17221844%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

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24 December 2019

PubMed publication ID

17221844

1 reference