A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans (Q33749557)

29 July 2017

title

A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans (English)

1 reference

29 July 2017

main subject

Caenorhabditis elegans

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9

Johan Auwerx

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Virginija Jovaisaite

4

Virginija Jovaisaite

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Adrienne Mottis

5

Adrienne Mottis

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Laurent Mouchiroud

2

Laurent Mouchiroud

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Xu Wang

Xu Wang

3

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Riekelt H Houtkooper

Riekelt H Houtkooper

8

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author name string

Pénélope A Andreux

1

1 reference

29 July 2017

Sabrina Bichet

6

1 reference

29 July 2017

Norman Moullan

7

1 reference

29 July 2017

language of work or name

English

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publication date

13 June 2014

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29 July 2017

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29 July 2017

volume

4

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29 July 2017

page(s)

5285

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The impact of mitochondrial oxidative stress on bile acid-like molecules in C. elegans provides a new perspective on human metabolic diseases

29 July 2017

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21 June 2018

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The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

21 June 2018

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Mitonuclear protein imbalance as a conserved longevity mechanism

21 June 2018

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Pharmacological approaches to restore mitochondrial function

21 June 2018

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Mitochondrial disorders as windows into an ancient organelle

21 June 2018

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Redeployment-based drug screening identifies the anti-helminthic niclosamide as anti-myeloma therapy that also reduces free light chain production

21 June 2018

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Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation

21 June 2018

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The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

21 June 2018

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A chemical screen probing the relationship between mitochondrial content and cell size

21 June 2018

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21 June 2018

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Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

21 June 2018

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21 June 2018

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Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

21 January 2018

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In vivo correction of COX deficiency by activation of the AMPK/PGC-1α axis

21 June 2018

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Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake

21 June 2018

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Regulation of cancer cell metabolism

21 June 2018

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Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial

21 June 2018

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Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials

21 June 2018

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Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans

21 June 2018

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Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

21 June 2018

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Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations

21 June 2018

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Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been

21 June 2018

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Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans

21 June 2018

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Large-scale chemical dissection of mitochondrial function

21 June 2018

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Mevalonate pathway: a review of clinical and therapeutical implications

21 June 2018

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21 June 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 June 2018

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Resveratrol improves health and survival of mice on a high-calorie diet

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.

21 June 2018

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Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.

21 June 2018

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A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

21 June 2018

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Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased life span

21 June 2018

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Control of developmental timing in Caenorhabditis elegans

21 June 2018

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Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

21 June 2018

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Mitochondrial diseases in man and mouse

21 June 2018

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Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S)

21 June 2018

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Determination of life-span in Caenorhabditis elegans by four clock genes

21 June 2018

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Bioluminescence of cellular ATP: a new method for evaluating cytotoxic agents in vitro.

21 June 2018

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Biochemical effects of miconazole on fungi. II. Inhibition of ergosterol biosynthesis in Candida albicans

21 June 2018

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Rates of behavior and aging specified by mitochondrial function during development

21 June 2018

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Crossref

https://api.crossref.org/works/10.1038%2FSREP05285

The many faces of insulin-like peptide signalling in the brain

21 January 2018

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Crossref

https://api.crossref.org/works/10.1038%2FSREP05285

Exposure to resveratrol triggers pharmacological correction of fatty acid utilization in human fatty acid oxidation-deficient fibroblasts

21 January 2018

1 reference

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Chlorination-induced enhancement of biological activities in imidazole antimycotics. A possible explanation to the molecular mechanism for their antimycotic activities

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Pharmacokinetic studies following systemic and topical administration of [14C]bifonazole in man

1 reference

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Inhibition of sterol biosynthesis in Candida albicans by imidazole-containing antifungals

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12 December 2020

Identifiers

DOI

10.1038/SREP05285

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference