Genetic abnormalities in chronic lymphocytic leukemia: where we are and where we go (Q33744997)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

review article

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title

Genetic abnormalities in chronic lymphocytic leukemia: where we are and where we go (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

chromosomal deletion syndrome

21 March 2020

main subject

lymphocyte

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5 references

3 April 2019

20 June 2019

30 June 2019

14 September 2019

18 December 2019

chronic lymphocytic leukemia

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3 April 2019

20 June 2019

30 June 2019

14 September 2019

18 December 2019

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14 September 2019

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18 December 2019

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1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Gonzalo Blanco

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Blanca Espinet

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Anna Puiggros

1

1 reference

29 July 2017

Gonzalo Blanco

2

1 reference

29 July 2017

Blanca Espinet

3

1 reference

29 July 2017

language of work or name

English

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publication date

22 May 2014

6 references

3 April 2019

20 June 2019

30 June 2019

14 September 2019

18 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

BioMed Research International

21 March 2020

published in

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3 April 2019

20 June 2019

30 June 2019

14 September 2019

18 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

2014

1 reference

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21 March 2020

page(s)

435983

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Creative Commons Attribution 3.0 Unported

21 March 2020

copyright license

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3 April 2019

20 June 2019

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14 September 2019

on focus list of Wikimedia project

18 December 2019

copyright status

copyrighted

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ScienceSource

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21 June 2018

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A comprehensive evaluation of the prognostic significance of 13q deletions in patients with B-chronic lymphocytic leukaemia

21 June 2018

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21 June 2018

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A high number of losses in 13q14 chromosome band is associated with a worse outcome and biological differences in patients with B-cell chronic lymphoid leukemia.

21 June 2018

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Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia

21 June 2018

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Array CGH analysis of chronic lymphocytic leukemia reveals frequent cryptic monoallelic and biallelic deletions of chromosome 22q11 that include the PRAME gene.

21 June 2018

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 June 2018

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Genomic aberrations and survival in chronic lymphocytic leukemia

21 June 2018

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Correlation of chromosome abnormalities with laboratory features and clinical course in B-cell chronic lymphocytic leukaemia

21 June 2018

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Integrative genomics analyses reveal molecularly distinct subgroups of B-cell chronic lymphocytic leukemia patients with 13q14 deletion.

21 June 2018

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13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia.

21 January 2018

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Clinical heterogeneity of de novo 11q deletion chronic lymphocytic leukaemia: prognostic relevance of extent of 11q deleted nuclei inside leukemic clone.

21 January 2018

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Biallelic deletion 13q14.3 in patients with chronic lymphocytic leukemia: cytogenetic, FISH and clinical studies

21 January 2018

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Chronic lymphocytic leukemia with del13q14 as the sole abnormality: dynamic prognostic estimate by interphase-FISH.

21 January 2018

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SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients.

21 January 2018

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21 January 2018

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B-cell receptor configuration and mutational analysis of patients with chronic lymphocytic leukaemia and trisomy 12 reveal recurrent molecular abnormalities.

21 January 2018

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Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations.

21 January 2018

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Gene expression signature of chronic lymphocytic leukaemia with Trisomy 12.

21 January 2018

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Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia.

21 January 2018

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Clonal evolution in CLL patients as detected by FISH versus chromosome banding analysis, and its clinical significance.

21 January 2018

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Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.

21 January 2018

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Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia with "normal" FISH: correlations with clinicobiologic parameters.

21 January 2018

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Structural alterations in chronic lymphocytic leukaemia. Cytogenetic and FISH analysis

21 January 2018

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Outcome of patients with relapsed or refractory chronic lymphocytic leukemia treated with flavopiridol: impact of genetic features

21 January 2018

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Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia.

21 January 2018

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MYC translocation in chronic lymphocytic leukaemia is associated with increased prolymphocytes and a poor prognosis.

21 January 2018

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A new genetic abnormality leading to TP53 gene deletion in chronic lymphocytic leukaemia

21 January 2018

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Comparison of array comparative genomic hybridization (aCGH) to FISH and cytogenetics in prognostic evaluation of chronic lymphocytic leukemia

21 January 2018

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High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

21 January 2018

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Genome-wide DNA profiling better defines the prognosis of chronic lymphocytic leukaemia.

21 January 2018

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Clonal evolution in chronic lymphocytic leukemia studied by interphase fluorescence in-situ hybridization.

21 January 2018

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Altered expression of p53 and MDM2 proteins in hematological malignancies.

21 January 2018

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Late appearance of the 11q22.3-23.1 deletion involving the ATM locus in B-cell chronic lymphocytic leukemia and related disorders. Clinico-biological significance

30 October 2018

1 reference

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Biallelic losses of 13q do not confer a poorer outcome in chronic lymphocytic leukaemia: analysis of 627 patients with isolated 13q deletion

30 October 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F435983

Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F435983

Clinical, immunophenotypic, and molecular profiling of trisomy 12 in chronic lymphocytic leukemia and comparison with other karyotypic subgroups defined by cytogenetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F435983

Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosis

21 January 2018

1 reference

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Genomic arrays in chronic lymphocytic leukemia routine clinical practice: are we ready to substitute conventional cytogenetics and fluorescencein situhybridization techniques?

21 January 2018

1 reference

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Gain of the short arm of chromosome 2 (2p) is a frequent recurring chromosome aberration in untreated chronic lymphocytic leukemia (CLL) at advanced stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F435983

Genome-wide DNA analysis identifies recurrent imbalances predicting outcome in chronic lymphocytic leukaemia with 17p deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F435983

Identification of a novel recurrent gain on 20q13 in chronic lymphocytic leukemia by array CGH and gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F435983

Chronic lymphocytic leukemia with 6q- shows distinct hematological features and intermediate prognosis

21 January 2018

1 reference

12 December 2020

Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status

1 reference

12 December 2020

Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities

1 reference

12 December 2020

p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs in chronic B-cell leukemias

1 reference

12 December 2020

Trisomy 12 defines a group of CLL with atypical morphology: correlation between cytogenetic, clinical and laboratory features in 544 patients

1 reference

12 December 2020

Cytogenetic, fluorescence in situ hybridisation, and clinical evaluation of translocations with concomitant deletion at 13q14 in chronic lymphocytic leukaemia

1 reference

12 December 2020

Incidence and clinical significance of 6q deletions in B cell chronic lymphocytic leukemia

1 reference

12 December 2020

Evidence for distinct pathomechanisms in genetic subgroups of chronic lymphocytic leukemia revealed by quantitative expression analysis of cell cycle, activation, and apoptosis-associated genes

1 reference

12 December 2020

Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia

1 reference

12 December 2020

Chronic lymphocytic leukaemia profiled for prognosis using a fluorescence in situ hybridisation panel

1 reference

12 December 2020

Immunostimulatory oligonucleotide-induced metaphase cytogenetics detect chromosomal aberrations in 80% of CLL patients: A study of 132 CLL cases with correlation to FISH, IgVH status, and CD38 expression

1 reference

12 December 2020

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia

1 reference

12 December 2020

Characterising the TP53-deleted subgroup of chronic lymphocytic leukemia: an analysis of additional cytogenetic abnormalities detected by interphase fluorescence in situ hybridisation and array-based comparative genomic hybridisation

1 reference

12 December 2020

Atypical 11q deletions identified by array CGH may be missed by FISH panels for prognostic markers in chronic lymphocytic leukemia

1 reference

12 December 2020

Translocation t(14;18) is not associated with inferior outcome in chronic lymphocytic leukemia

1 reference

12 December 2020

Independent coexistence of clones with 13q14 deletion at reciprocal translocation breakpoint and 13q14 interstitial deletion in chronic lymphocytic leukemia

1 reference

12 December 2020

13q deletions in B-cell lymphoproliferative disorders: frequent association with translocation

1 reference

12 December 2020

Trisomy 19 is associated with trisomy 12 and mutatedIGHVgenes in B-chronic lymphocytic leukaemia

1 reference

12 December 2020

Chromosomal translocations independently predict treatment failure, treatment-free survival and overall survival in B-cell chronic lymphocytic leukemia patients treated with cladribine

1 reference

12 December 2020

Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival

1 reference

12 December 2020

Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping

1 reference

12 December 2020

Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia

1 reference

12 December 2020

Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients

1 reference

12 December 2020

Chromosomal aberrations in chronic lymphocytic leukemia detected by conventional cytogenetics with DSP30 as a single agent: comparison with FISH

1 reference

12 December 2020

Chronic lymphocytic leukemia and prolymphocytic leukemia with MYC translocations: a subgroup with an aggressive disease course

1 reference

12 December 2020

Chronic lymphocytic leukemia with deletion 17p: emerging treatment options

1 reference

12 December 2020

Chronic lymphocytic leukaemia with 17p deletion: a retrospective analysis of prognostic factors and therapy results

1 reference

12 December 2020

microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia

1 reference

12 December 2020

TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations

1 reference

12 December 2020

Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/435983

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24967369%20AND%20SRC:MED&resulttype=core&format=json