A chemical and phosphoproteomic characterization of dasatinib action in lung cancer (Q33742159)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190765%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer (English)

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19 January 2020

main subject

dasatinib monohydrate

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1 reference

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11

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19 January 2020

Jacques Colinge

6

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19 January 2020

7

Keiryn L Bennett

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19 January 2020

9

Lanxi Song

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19 January 2020

2

Uwe Rix

1 reference

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19 January 2020

10

Steven Eschrich

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19 January 2020

12

John Koomen

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19 January 2020

13

Eric B Haura

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19 January 2020

author name string

Jiannong Li

1

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19 January 2020

Bin Fang

3

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19 January 2020

Yun Bai

4

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19 January 2020

Arthur Edwards

5

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19 January 2020

Jingchun Gao

8

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19 January 2020

publication date

28 February 2010

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19 January 2020

published in

Nature Chemical Biology

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19 January 2020

volume

6

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19 January 2020

issue

4

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19 January 2020

page(s)

291-299

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Src kinases as therapeutic targets for cancer

19 January 2020

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21 June 2018

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21 June 2018

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21 June 2018

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The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

21 June 2018

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Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells

21 June 2018

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A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts

21 June 2018

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Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma

21 June 2018

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SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines

21 June 2018

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Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation

21 June 2018

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Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling

21 June 2018

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Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

21 June 2018

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Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival

21 June 2018

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ILK, PINCH and parvin: the tIPP of integrin signalling

21 June 2018

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21 June 2018

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Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

21 June 2018

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21 June 2018

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Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

21 June 2018

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21 June 2018

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Increased expression of integrin-linked kinase is associated with shorter survival in non-small cell lung cancer

21 June 2018

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21 June 2018

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SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

A renaissance for SRC

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21 June 2018

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 June 2018

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Development of human protein reference database as an initial platform for approaching systems biology in humans

21 June 2018

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Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck

21 June 2018

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The nonreceptor tyrosine kinase ACK2, a specific target for Cdc42 and a negative regulator of cell growth and focal adhesion complexes

21 June 2018

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21 June 2018

The hunting of the Src

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Oncogenic kinase signalling

21 June 2018

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Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation

21 June 2018

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Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

21 June 2018

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Tyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulation

21 June 2018

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A kinase-negative epidermal growth factor receptor that retains the capacity to stimulate DNA synthesis

21 June 2018

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Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha

21 June 2018

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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

21 June 2018

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Epidermal‐Growth‐Factor‐Dependent Activation of the Src‐Family Kinases

21 June 2018

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High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains

21 June 2018

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Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model

21 June 2018

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Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

30 October 2018

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EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy.

30 October 2018

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30 October 2018

Identifiers

DOI

10.1038/NCHEMBIO.332

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190765%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

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19 January 2020

PubMed publication ID

20190765

1 reference