Is cancer vaccination feasible at older age? (Q33739907)

29 July 2017

title

Is cancer vaccination feasible at older age? (English)

1 reference

29 July 2017

Claudia Gravekamp

1

1 reference

29 July 2017

Arthee Jahangir

series ordinal

2

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29 July 2017

publication date

6 February 2014

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29 July 2017

published in

Experimental Gerontology

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29 July 2017

volume

54

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29 July 2017

page(s)

138-144

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Curcumin improves the therapeutic efficacy of Listeria(at)-Mage-b vaccine in correlation with improved T-cell responses in blood of a triple-negative breast cancer model 4T1.

29 July 2017

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Myeloid-derived suppressor cells have a central role in attenuated Listeria monocytogenes-based immunotherapy against metastatic breast cancer in young and old mice

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Nontoxic radioactive Listeria(at) is a highly effective therapy against metastatic pancreatic cancer

21 June 2018

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Blood CD33(+)HLA-DR(-) myeloid-derived suppressor cells are increased with age and a history of cancer

21 June 2018

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Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.

21 June 2018

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21 June 2018

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21 June 2018

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The effect of ageing on macrophage Toll-like receptor-mediated responses in the fight against pathogens

21 June 2018

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21 June 2018

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Bacteria in cancer therapy: a novel experimental strategy

21 June 2018

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Vaccination with Mage-b DNA induces CD8 T-cell responses at young but not old age in mice with metastatic breast cancer

21 June 2018

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High efficacy of a Listeria-based vaccine against metastatic breast cancer reveals a dual mode of action

21 June 2018

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The first clinical use of a live-attenuated Listeria monocytogenes vaccine: a Phase I safety study of Lm-LLO-E7 in patients with advanced carcinoma of the cervix

21 June 2018

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Myeloid-derived suppressor cells: linking inflammation and cancer

21 June 2018

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The importance of the age factor in cancer vaccination at older age.

21 June 2018

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The cancer vaccine roller coaster

21 June 2018

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Myeloid-derived suppressor cells as regulators of the immune system

21 June 2018

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Mechanisms of murine dendritic cell antitumor dysfunction in aging

21 June 2018

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Mage-b vaccine delivered by recombinant Listeria monocytogenes is highly effective against breast cancer metastases.

21 June 2018

1 reference

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An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial

21 June 2018

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Innate immunity and aging

21 June 2018

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NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy

21 June 2018

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21 June 2018

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Altered macrophage differentiation and immune dysfunction in tumor development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

21 June 2018

1 reference

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Role of T lymphocyte replicative senescence in vaccine efficacy

21 June 2018

1 reference

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Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer

21 June 2018

1 reference

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Immune suppression in the tumor microenvironment

21 June 2018

1 reference

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Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients

21 June 2018

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Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma

21 June 2018

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Immunotherapy with autologous tumor cell-BCG vaccine in patients with colon cancer: a prospective study of medical and economic benefits

21 June 2018

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Aged mice develop protective antitumor immune responses with appropriate costimulation

21 June 2018

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NK and NKT cell functions in immunosenescence

21 June 2018

1 reference

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Replicative senescence of CD8 T cells: effect on human ageing

21 June 2018

1 reference

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Aging and innate immune cells

21 June 2018

1 reference

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Visualization of tumors and metastases in live animals with bacteria and vaccinia virus encoding light-emitting proteins

21 June 2018

1 reference

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Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: phase III, randomised controlled trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Applying the principles of stem-cell biology to cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Cytokines in cancer pathogenesis and cancer therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Liver NKT cells: an account of heterogeneity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Natural versus adaptive regulatory T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

NK cells and NKT cells in innate defense against viral infections

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

IL-7 is critical for homeostatic proliferation and survival of naive T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Differential tumor surveillance by natural killer (NK) and NKT cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Active specific immunotherapy for stage II and stage III human colon cancer: a randomised trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Changes in the Aging Immune System

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

The aging immune system: primer and prospectus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Delayed cutaneous hypersensitivity to autologous tumor cells in colorectal cancer patients immunized with an autologous tumor cell: Bacillus Calmette-Guérin vaccine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Differential age-change in the numbers of CD4+CD45RA+ and CD4+CD29+ T cell subsets in human peripheral blood

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

A New Mechanism for Blocking Myeloid-Derived Suppressor Cells by CpG

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Depleting intratumoral CD4+CD25+ regulatory T cells via FasL protein transfer enhances the therapeutic efficacy of adoptive T cell transfer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

In vivo ethanol exposure down-regulates TLR2-, TLR4-, and TLR9-mediated macrophage inflammatory response by limiting p38 and ERK1/2 activation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Nonantigen specific CD8+ T suppressor lymphocytes originate from CD8+CD28- T cells and inhibit both T-cell proliferation and CTL function.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Natural Killer Cells Activated by MHC Class ILow Targets Prime Dendritic Cells to Induce Protective CD8 T Cell Responses

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Prognostic model for predicting survival in men with hormone-refractory metastatic prostate cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Effective cancer targeting using an anti-tumor tissue vascular endothelium-specific monoclonal antibody (TES-23).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Efficacy of cancer gene therapy in aging: adenocarcinoma cells engineered to release IL-2 are rejected but do not induce tumor specific immune memory in old mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Split-virus influenza vaccines: do they provide adequate immunity in the elderly?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053252

Increase of plasma IL-6 concentration with age in healthy subjects

30 October 2018

1 reference

12 December 2020

Natural Killer Cells in the Late Decades of Human Life

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12 December 2020

Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer

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12 December 2020

Aging affect the anti-tumor potential of dendritic cell vaccination, but it can be overcome by co-stimulation with anti-OX40 or anti-4-1BB

1 reference

12 December 2020

Peripheral blood dendritic cells and monocytes are differently regulated in the elderly

1 reference

12 December 2020

Potentiation of antitumor effect of NKT cell ligand, alpha-galactosylceramide by combination with IL-12 on lung metastasis of malignant melanoma cells

1 reference

12 December 2020

Depletion of CD4+ CD25+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes

1 reference

12 December 2020

CpG-DNA stimulates cellular and humoral immunity and promotes Th1 differentiation in aged BALB/c mice

1 reference

12 December 2020

A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors

1 reference

12 December 2020

Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report

1 reference

12 December 2020

Low effectiveness of DNA vaccination against HER-2/neu in ageing

1 reference

12 December 2020

Effect of aging on epidermal dendritic cell populations in C57BL/6J mice

1 reference

12 December 2020

In vitro and in vivo activation of CD4+ lymphocytes by autologous tumor cells

1 reference

12 December 2020

Depletion of CD4+CD25+ human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro

1 reference

12 December 2020

Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria

1 reference

12 December 2020

Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction

1 reference

12 December 2020

Anti-CD40 antibody induces antitumor and antimetastatic effects: the role of NK cells

1 reference

12 December 2020

10.1016/J.EXGER.2014.01.025

Identifiers

DOI

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29 July 2017

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29 July 2017

1 reference