Chemical approaches to the study of protein tyrosine kinases and their implications for mechanism and inhibitor design (Q33716117)

28 July 2017

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title

Chemical approaches to the study of protein tyrosine kinases and their implications for mechanism and inhibitor design (English)

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28 July 2017

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Cole PA

1

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28 July 2017

Sondhi D

series ordinal

2

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28 July 2017

Kim K

series ordinal

3

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28 July 2017

publication date

1 May 1999

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Pharmacology & Therapeutics

28 July 2017

published in

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28 July 2017

volume

82

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28 July 2017

issue

2-3

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28 July 2017

page(s)

219-229

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Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments

28 July 2017

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Correlation of the phosphorylation states of pp60c-src with tyrosine kinase activity: the intramolecular pY530-SH2 complex retains significant activity if Y419 is phosphorylated

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Detection of a physical and functional interaction between Csk and Lck which involves the SH2 domain of Csk and is mediated by autophosphorylation of Lck on tyrosine 394

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The role of the catalytic base in the protein tyrosine kinase Csk

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Adenosine cyclic 3',5'-monophosphate dependent protein kinase: kinetic mechanism for the bovine skeletal muscle catalytic subunit

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Synthesis of proteins by native chemical ligation

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Semisynthesis of cytotoxic proteins using a modified protein splicing element

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Divalent ion effects and insights into the catalytic mechanism of protein tyrosine kinase Csk

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Magnetic resonance measurements of intersubstrate distances at the active site of protein kinase using substitution-inert cobalt(III) and chromium(III) complexes of adenosine 5'-(beta, gamma-methylenetriphosphate)

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Pre-steady-state kinetic analysis of cAMP-dependent protein kinase using rapid quench flow techniques

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Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

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Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

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A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

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7 January 2021

Enzyme-Catalyzed Phosphoryl Transfer Reactions

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7 January 2021

Rapid and efficient purification of Src homology 2 domain-containing proteins: Fyn, Csk and phosphatidylinositol 3-kinase p85

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Tyrosine kinase inhibition: an approach to drug development

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cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer

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Ras-catalyzed hydrolysis of GTP: a new perspective from model studies

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Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

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7 January 2021

Expressed protein ligation: a general method for protein engineering

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7 January 2021

A general method for site-specific incorporation of unnatural amino acids into proteins.

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7 January 2021

Sequence specificity of C-terminal Src kinase (CSK)--a comparison with Src-related kinases c-Fgr and Lyn.

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7 January 2021

Possible v-Crk-induced transformation through activation of Src kinases.

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7 January 2021

Expressed protein ligation, a novel method for studying protein-protein interactions in transcription

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7 January 2021

Tyrosine kinases: modular signaling enzymes with tunable specificities

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7 January 2021

Crystal structure of the Src family tyrosine kinase Hck

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7 January 2021

Peptide and protein phosphorylation by protein tyrosine kinase Csk: insights into specificity and mechanism

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7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

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7 January 2021

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

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7 January 2021

Structure-function relationships in Src family and related protein tyrosine kinases

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7 January 2021

Three-dimensional structure of the tyrosine kinase c-Src

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7 January 2021

Chemical mechanism of the adenosine cyclic 3',5'-monophosphate dependent protein kinase from pH studies

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7 January 2021

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor

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7 January 2021

10.1016/S0163-7258(98)00046-1

Identifiers

DOI

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28 July 2017

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