Janus kinases and their role in growth and disease (Q33664276)

28 July 2017

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title

Janus kinases and their role in growth and disease (English)

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28 July 2017

Aringer M

1

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28 July 2017

Cheng A

2

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28 July 2017

Nelson JW

3

1 reference

28 July 2017

Chen M

4

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28 July 2017

Sudarshan C

5

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28 July 2017

Zhou YJ

6

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28 July 2017

O'Shea JJ

7

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28 July 2017

language of work or name

English

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publication date

1 January 1999

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28 July 2017

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28 July 2017

volume

64

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28 July 2017

issue

24

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28 July 2017

page(s)

2173-2186

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Cytokine signaling through nonreceptor protein tyrosine kinases

28 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Jaks and STATs: biological implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Molecular cloning of rat JAK3, a novel member of the JAK family of protein tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Two members of the JAK family of protein tyrosine kinases map to chromosomes 1p31.3 and 9p24

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Genomic sequence, organization, and chromosomal localization of human JAK3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Apolipoprotein A-I conformation in reconstituted discoidal lipoproteins varying in phospholipid and cholesterol content

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Cytokine signal transduction and the JAK family of protein tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Definition of the interferon-alpha receptor-binding domain on the TYK2 kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Co-expressed complementary fragments of the human red cell anion exchanger (band 3, AE1) generate stilbene disulfonate-sensitive anion transport

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

inferred from DOI database lookup

7 January 2021

based on heuristic

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Interferon-induced nuclear signalling by Jak protein tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Cytokine receptor signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

IL4 and IL13 receptors share the γc chain and activate STAT6, STAT3 and STAT5 proteins in normal human B cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Signal transduction pathway of interleukin-4 and interleukin-13 in human B cells derived from X-linked severe combined immunodeficiency patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

STATs and Gene Regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Tissue-specific Pattern of Stress Kinase Activation in Ischemic/Reperfused Heart and Kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Specific Inhibition of Stat3 Signal Transduction by PIAS3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

A family of cytokine-inducible inhibitors of signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

A new protein containing an SH2 domain that inhibits JAK kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Structure and function of a new STAT-induced STAT inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Cloning and Functional Analysis of New Members of STAT Induced STAT Inhibitor (SSI) Family: SSI-2 and SSI-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Cloning and characterization of novel CIS family genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Cytokine signaling: Cytokine-inducible signaling inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

SOCS-1/JAB/SSI-1 Can Bind to and Suppress Tec Protein-tyrosine Kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Protein kinase C contains a pseudosubstrate prototope in its regulatory domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Identification of SOCS-3 as a potential mediator of central leptin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

The JAK-STAT pathway in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Defective lymphoid development in mice lacking Jak3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

The interleukin-2 receptor gamma chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Crucial role of Jak3 in negative selection of self-reactive T cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Peripheral expression of Jak3 is required to maintain T lymphocyte function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Jak2 is essential for signaling through a variety of cytokine receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Human severe combined immunodeficiency: genetic, phenotypic, and functional diversity in one hundred eight infants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Immunodeficiencies caused by genetic defects in protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

The molecular basis of X-linked severe combined immunodeficiency: defective cytokine receptor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

The Drosophila Tumorous-lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

An amino acid substitution in the Drosophila hopTum-l Jak kinase causes leukemia-like hematopoietic defects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Jak-STAT signaling induced by the v-abl oncogene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2898%2900538-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0024-3205(98)00538-4

1 reference

28 July 2017

1 reference