Mitochondrial metabolism and diabetes (Q33609715)

28 July 2017

title

Mitochondrial metabolism and diabetes (English)

1 reference

28 July 2017

Soo Heon Kwak

1

0 references

author name string

Kyong Soo Park

series ordinal

2

1 reference

28 July 2017

Ki-Up Lee

series ordinal

3

1 reference

28 July 2017

Hong Kyu Lee

series ordinal

4

1 reference

28 July 2017

publication date

1 October 2010

1 reference

Journal of Diabetes Investigation

28 July 2017

published in

1 reference

28 July 2017

volume

1

1 reference

28 July 2017

issue

5

1 reference

28 July 2017

page(s)

161-169

1 reference

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28 July 2017

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Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.

21 June 2018

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Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance

21 June 2018

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21 June 2018

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Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

21 June 2018

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Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial

21 June 2018

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21 June 2018

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Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways

21 June 2018

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21 June 2018

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Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

21 June 2018

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Mitochondrial fission and fusion dynamics: the long and short of it

21 June 2018

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Economic costs of diabetes in the U.S. In 2007.

21 June 2018

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Clinical features, diagnosis and management of maternally inherited diabetes and deafness (MIDD) associated with the 3243A>G mitochondrial point mutation

21 June 2018

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A mitochondrial DNA variant at position 16189 is associated with type 2 diabetes mellitus in Asians.

21 June 2018

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Intracellular fatty acid metabolism in skeletal muscle and insulin resistance

21 June 2018

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 June 2018

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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

21 June 2018

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Common variants in WFS1 confer risk of type 2 diabetes

21 June 2018

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Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance.

21 June 2018

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Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

21 June 2018

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Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis

21 June 2018

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Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians

21 June 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 June 2018

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Epidemic obesity and type 2 diabetes in Asia

21 June 2018

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Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance

21 June 2018

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Mitochondrial fusion and fission in mammals

21 June 2018

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New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome

21 June 2018

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Genetic basis of maturity-onset diabetes of the young

21 June 2018

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Minireview: implication of mitochondria in insulin secretion and action

21 June 2018

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

21 June 2018

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AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.

21 June 2018

1 reference

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A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

21 June 2018

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FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

21 June 2018

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

21 June 2018

1 reference

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Molecular mechanisms of mitochondrial diabetes (MIDD).

21 June 2018

1 reference

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The role of mitochondrial DNA in the development of type 2 diabetes caused by fetal malnutrition

21 June 2018

1 reference

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 June 2018

1 reference

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Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

21 June 2018

1 reference

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Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

21 June 2018

1 reference

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The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

21 June 2018

1 reference

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Effects of purifying and adaptive selection on regional variation in human mtDNA.

21 June 2018

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Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation

21 June 2018

1 reference

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Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

21 June 2018

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

21 June 2018

1 reference

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Mitochondrial dysfunction in the elderly: possible role in insulin resistance

21 June 2018

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

21 June 2018

1 reference

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Mitochondrial function in normal and diabetic beta-cells

21 June 2018

1 reference

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Global and societal implications of the diabetes epidemic

21 June 2018

1 reference

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A transcription factor regulatory circuit in differentiated pancreatic cells

21 June 2018

1 reference

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Glutathione-S-transferase family of enzymes.

21 June 2018

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WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain

21 June 2018

1 reference

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Mitochondria, oxygen free radicals, disease and ageing

21 June 2018

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 June 2018

1 reference

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Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha.

21 June 2018

1 reference

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Functional and morphological abnormalities of mitochondria harbouring the tRNA(Leu)(UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Oxidative phosphorylation at the fin de siècle

21 June 2018

1 reference

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Mitochondrial diseases in man and mouse

21 June 2018

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Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion

21 June 2018

1 reference

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21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

A common mitochondrial DNA variant is associated with insulin resistance in adult life

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Stimulus-secretion coupling in pancreatic beta cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Maternally inherited diabetes and deafness is a distinct subtype of diabetes and associates with a single point mutation in the mitochondrial tRNA(Leu(UUR)) gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Sequence and organization of the human mitochondrial genome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Toxicology of various pesticides and their decomposition products on mitochondrial electron transport.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

A mutation in the tRNA(Leu)(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Gamma-glutamyltransferase and diabetes--a 4 year follow-up study

21 June 2018

1 reference

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The clinical variability of maternally inherited diabetes and deafness is associated with the degree of heteroplasmy in blood leukocytes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Peripheral blood mitochondrial DNA content and dysregulation of glucose metabolism

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

The insulin-sensitizing effect of rosiglitazone in type 2 diabetes mellitus patients does not require improved in vivo muscle mitochondrial function

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Alpha-lipoic acid prevents endothelial dysfunction in obese rats via activation of AMP-activated protein kinase

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

alpha-Lipoic acid prevents diabetes mellitus in diabetes-prone obese rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Changes of mitochondrial DNA content in the male offspring of protein-malnourished rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Lipolysis in skeletal muscle is decreased in high-fat-fed rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Fetal and Early Postnatal Protein Malnutrition Cause Long-Term Changes in Rat Liver and Muscle Mitochondria

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

The prevalence of the mitochondrial DNA 16189 variant in non-diabetic Korean adults and its association with higher fasting glucose and body mass index

30 October 2018

1 reference

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Islet cell autoimmunity and mitochondrial DNA mutation in Korean subjects with typical and atypical Type I diabetes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Peripheral blood mitochondrial DNA content is related to insulin sensitivity in offspring of type 2 diabetic patients

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Decreased mitochondrial DNA content in peripheral blood precedes the development of non-insulin-dependent diabetes mellitus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020716

Mitochondrial adaptations in denervated muscle: relationship to muscle performance

30 October 2018

1 reference

12 December 2020

Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2

1 reference

12 December 2020

Role of the mitochondrial DNA 16184–16193 poly-C tract in type 2 diabetes

1 reference

12 December 2020

Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion

1 reference

12 December 2020

Reduced peripheral blood mitochondrial DNA content is not a risk factor for Type 2 diabetes

1 reference

12 December 2020

Association between serum concentrations of persistent organic pollutants and gamma glutamyltransferase: results from the National Health and Examination Survey 1999-2002

1 reference

12 December 2020

Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion

1 reference

12 December 2020

Phenotype-genotype correlations in a series of wolfram syndrome families

1 reference

12 December 2020

Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects

1 reference

12 December 2020

10.1111/J.2040-1124.2010.00047.X

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference