Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice (Q33604863)

28 July 2017

title

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice (English)

1 reference

28 July 2017

1 reference

8

Gregory J Gores

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28 July 2017

11

Eduardo Nunes Chini

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28 July 2017

7

Jan van Deursen

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28 July 2017

Carlos Escande

1

1 reference

28 July 2017

Claudia C S Chini

2

1 reference

28 July 2017

Veronica Nin

3

1 reference

28 July 2017

Katherine Minter Dykhouse

4

1 reference

28 July 2017

Colleen M Novak

5

1 reference

28 July 2017

James Levine

6

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28 July 2017

Junjie Chen

9

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28 July 2017

Zhenkun Lou

10

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28 July 2017

language of work or name

English

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publication date

11 January 2010

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Journal of Clinical Investigation

28 July 2017

published in

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28 July 2017

volume

120

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28 July 2017

issue

2

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28 July 2017

page(s)

545-558

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Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

28 July 2017

cites work

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Inhibition of SUV39H1 methyltransferase activity by DBC1

28 July 2018

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Deleted in breast cancer 1, a novel androgen receptor (AR) coactivator that promotes AR DNA-binding activity

28 July 2018

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Phosphorylation regulates SIRT1 function.

28 July 2018

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SirT1 gain of function increases energy efficiency and prevents diabetes in mice

28 July 2018

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The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

28 July 2018

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SIRT1 is a circadian deacetylase for core clock components

28 July 2018

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Sirt1 protects against high-fat diet-induced metabolic damage

28 July 2018

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28 July 2018

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28 July 2018

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Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

28 July 2018

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Sirtuins in aging and disease

28 July 2018

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SirT1 regulates energy metabolism and response to caloric restriction in mice

28 July 2018

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Negative regulation of the deacetylase SIRT1 by DBC1

28 July 2018

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Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

28 July 2018

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SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress

28 July 2018

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Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

28 July 2018

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Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1

28 July 2018

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Modulation of estrogen receptor alpha protein level and survival function by DBC-1.

28 July 2018

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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

28 July 2018

1 reference

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Phosphorylation of HuR by Chk2 regulates SIRT1 expression

28 July 2018

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The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals

28 July 2018

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A human hepatocellular in vitro model to investigate steatosis.

28 July 2018

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Sirtuins as potential targets for metabolic syndrome

28 July 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

28 July 2018

1 reference

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A probability-based approach for high-throughput protein phosphorylation analysis and site localization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Nampt/PBEF/Visfatin: a regulator of mammalian health and longevity?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

28 July 2018

1 reference

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

28 July 2018

1 reference

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Calorie restriction--the SIR2 connection

28 July 2018

1 reference

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AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells

28 July 2018

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Large-scale characterization of HeLa cell nuclear phosphoproteins

28 July 2018

1 reference

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

28 July 2018

1 reference

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state

28 July 2018

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Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

28 July 2018

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

28 July 2018

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Negative control of p53 by Sir2alpha promotes cell survival under stress

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

The anti-aging, metabolism potential of SIRT1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Resveratrol alleviates alcoholic fatty liver in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

DBC1 is a negative regulator of SIRT1

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

SIRT1 promotes DNA repair activity and deacetylation of Ku70

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Regulation of intracellular levels of NAD: a novel role for CD38.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

New functions of a long-known molecule. Emerging roles of NAD in cellular signaling

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810074

Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38

30 October 2018

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12 December 2020

The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats

1 reference

12 December 2020

Mammalian sirtuin 1 is involved in the protective action of dietary saturated fat against alcoholic fatty liver in mice

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12 December 2020

Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis

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12 December 2020

Identifiers

DOI

10.1172/JCI39319

1 reference

28 July 2017

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28 July 2017

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