Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease (Q33604010)

28 July 2017

title

Protein Kinase Signaling at the Crossroads of Myocyte Life and Death in Ischemic Heart Disease (English)

1 reference

28 July 2017

main subject

coronary artery disease

1 reference

Thomas Force

5

0 references

John W. Elrod

object named as

John W Elrod

3

0 references

author name string

Ronald J Vagnozzi

1

1 reference

28 July 2017

Nicholas E Hoffman

2

1 reference

28 July 2017

Muniswamy Madesh

4

1 reference

28 July 2017

publication date

1 January 2012

1 reference

Drug Discovery Today: Therapeutic Strategies

28 July 2017

published in

1 reference

28 July 2017

volume

9

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28 July 2017

issue

4

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28 July 2017

page(s)

e173-e182

1 reference

Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

28 July 2017

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21 June 2018

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Bax regulates primary necrosis through mitochondrial dynamics

21 June 2018

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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

21 June 2018

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21 June 2018

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Location matters: clarifying the concept of nuclear and cytosolic CaMKII subtypes

21 June 2018

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Protective role of transient pore openings in calcium handling by cardiac mitochondria

21 June 2018

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How and When Do Myocytes Die During Ischemia and Reperfusion: The Late Phase

21 June 2018

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Unraveling the secrets of a double life: contractile versus signaling Ca2+ in a cardiac myocyte

21 June 2018

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Programmed necrosis, not apoptosis, in the heart

21 June 2018

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Two candidates at the heart of dysfunction: The ryanodine receptor and calcium/calmodulin protein kinase II as potential targets for therapeutic intervention-An in vivo perspective.

21 June 2018

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CaMKII in myocardial hypertrophy and heart failure

21 June 2018

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Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice

21 June 2018

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21 June 2018

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Cell death in the pathogenesis of heart disease: mechanisms and significance

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

21 June 2018

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Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

A CaPful of mechanisms regulating the mitochondrial permeability transition

21 June 2018

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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 June 2018

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p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity

21 June 2018

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TNF-alpha induces two distinct caspase-8 activation pathways

21 June 2018

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A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation

21 June 2018

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Identification of RIP1 kinase as a specific cellular target of necrostatins

21 June 2018

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Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury

21 June 2018

1 reference

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Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

21 June 2018

1 reference

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The cardioprotective effect of necrostatin requires the cyclophilin-D component of the mitochondrial permeability transition pore

21 June 2018

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Myocardial reperfusion injury.

21 June 2018

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PKB and the mitochondria: AKTing on apoptosis

21 June 2018

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Necrostatin: a potentially novel cardioprotective agent?

21 June 2018

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TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

21 June 2018

1 reference

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Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

21 June 2018

1 reference

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Into the heart: the emerging role of the ubiquitin-proteasome system.

21 June 2018

1 reference

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Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole

21 June 2018

1 reference

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Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation

21 June 2018

1 reference

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Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

21 June 2018

1 reference

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Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligase

21 June 2018

1 reference

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Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Mitochondrial bound hexokinase activity as a preventive antioxidant defense: steady-state ADP formation as a regulatory mechanism of membrane potential and reactive oxygen species generation in mitochondria.

21 June 2018

1 reference

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Essential roles of receptor-interacting protein and TRAF2 in oxidative stress-induced cell death

21 June 2018

1 reference

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Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

21 June 2018

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Inhibitors of protein kinase signaling pathways: emerging therapies for cardiovascular disease.

21 June 2018

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Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury

21 June 2018

1 reference

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Regulation of cell death: the calcium-apoptosis link

21 June 2018

1 reference

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Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.

21 June 2018

1 reference

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 June 2018

1 reference

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Pathophysiological and protective roles of mitochondrial ion channels

21 June 2018

1 reference

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From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state

21 June 2018

1 reference

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Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases

21 June 2018

1 reference

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p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes

21 June 2018

1 reference

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Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore

21 June 2018

1 reference

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RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

21 June 2018

1 reference

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Inhibition of calcium/calmodulin-dependent protein kinase kinase β and calcium/calmodulin-dependent protein kinase IV is detrimental in cerebral ischemia

21 June 2018

1 reference

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CaMKII does it again: even the mitochondria cannot escape its influence

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo.

30 October 2018

1 reference

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Regulation of mitochondrial processes: a target for heart failure

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Inhibition of Elevated Ca 2+ /Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Angiotensin II-induced oxidative stress resets the Ca2+ dependence of Ca2+-calmodulin protein kinase II and promotes a death pathway conserved across different species

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Mitochondrial calcium in health and disease

30 October 2018

1 reference

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Reactive oxygen species production by potato tuber mitochondria is modulated by mitochondrially bound hexokinase activity.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Inhibition of GSK3beta by postconditioning is required to prevent opening of the mitochondrial permeability transition pore during reperfusion

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

NF-kappaB protects macrophages from lipopolysaccharide-induced cell death: the role of caspase 8 and receptor-interacting protein

30 October 2018

1 reference

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Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Is p53 the Long-Sought Molecular Trigger for Cyclophilin D–Regulated Mitochondrial Permeability Transition Pore Formation and Necrosis?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019409

Erythropoietin affords additional cardioprotection to preconditioned hearts by enhanced phosphorylation of glycogen synthase kinase-3 beta

30 October 2018

1 reference

12 December 2020

CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury

1 reference

12 December 2020

Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo

1 reference

12 December 2020

Activation of CaMKIIdeltaC is a common intermediate of diverse death stimuli-induced heart muscle cell apoptosis

1 reference

12 December 2020

10.1016/J.DDSTR.2013.12.001

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference