Signal integration and gene induction by a functionally distinct STAT3 phosphoform (Q33602531)

28 July 2017

title

Signal integration and gene induction by a functionally distinct STAT3 phosphoform (English)

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28 July 2017

Matthew S Waitkus

1

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28 July 2017

Unni M Chandrasekharan

2

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28 July 2017

Belinda Willard

3

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28 July 2017

Thomas L Tee

4

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28 July 2017

Jason K Hsieh

5

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28 July 2017

Christopher G Przybycin

6

1 reference

28 July 2017

Brian I Rini

7

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28 July 2017

Paul E Dicorleto

8

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28 July 2017

language of work or name

English

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publication date

10 March 2014

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Molecular and Cellular Biology

28 July 2017

published in

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28 July 2017

volume

34

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28 July 2017

issue

10

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28 July 2017

page(s)

1800-1811

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STAT3-mediated coincidence detection regulates noncanonical immediate early gene induction

28 July 2017

cites work

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First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy.

14 July 2018

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14 July 2018

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14 July 2018

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What Are the bona fide GSK3 Substrates?

14 July 2018

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STAT3-dependent effects of IL-22 in human keratinocytes are counterregulated by sirtuin 1 through a direct inhibition of STAT3 acetylation

14 July 2018

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Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

14 July 2018

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Disruption of Protein Arginine N -Methyltransferase 2 Regulates Leptin Signaling and Produces Leanness In Vivo Through Loss of STAT3 Methylation

14 July 2018

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STAT3 inhibitor WP1066 as a novel therapeutic agent for renal cell carcinoma

14 July 2018

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STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells

14 July 2018

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Glycogen synthase kinase-3: a new therapeutic target in renal cell carcinoma

14 July 2018

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STATs in cancer inflammation and immunity: a leading role for STAT3

14 July 2018

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Src kinases as therapeutic targets for cancer

14 July 2018

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Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.

14 July 2018

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Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.

14 July 2018

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Acetylation and activation of STAT3 mediated by nuclear translocation of CD44.

14 July 2018

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STAT3 inhibition of gluconeogenesis is downregulated by SirT1

14 July 2018

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Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells

14 July 2018

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Activation of signal transducer and activator of transcription 3 through a phosphomimetic serine 727 promotes prostate tumorigenesis independent of tyrosine 705 phosphorylation

14 July 2018

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A quantitative atlas of mitotic phosphorylation

14 July 2018

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Roles of unphosphorylated STATs in signaling

14 July 2018

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Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer

14 July 2018

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Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB

14 July 2018

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Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity

14 July 2018

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Sorafenib in advanced clear-cell renal-cell carcinoma

14 July 2018

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Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

14 July 2018

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Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models

14 July 2018

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STAT3: a multifaceted oncogene

14 July 2018

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Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites

14 July 2018

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Stat3 dimerization regulated by reversible acetylation of a single lysine residue

14 July 2018

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Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells

14 July 2018

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STATs dimerize in the absence of phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Ser727-dependent transcriptional activation by association of p300 with STAT3 upon IL-6 stimulation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Three-dimensional structure of the Stat3beta homodimer bound to DNA

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

STAT3 Serine Phosphorylation by ERK-Dependent and -Independent Pathways Negatively Modulates Its Tyrosine Phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Thrombin causes increased monocytic-cell adhesion to endothelial cells through a protein kinase C-dependent pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

GSK-3 inhibition in vitro and in vivo enhances antitumor effect of sorafenib in renal cell carcinoma (RCC).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Activation of Stat3 in renal tumors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Antitumor effects of sunitinib or sorafenib in patients with metastatic renal cell carcinoma who received prior antiangiogenic therapy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Phosphorylation of STAT3 serine-727 by cyclin-dependent kinase 1 is critical for nocodazole-induced mitotic arrest

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

The immediate early genes Fos and Egr1 become STAT1 transcriptional targets in the absence of STAT3

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019034

30 October 2018

Identifiers

DOI

10.1128/MCB.00034-14

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28 July 2017

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28 July 2017

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