Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma. (Q33601156)

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3 March 2020

title

Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma (English)

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4

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Andrew L. Kung

12

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Richard A. Young

14

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10

John G Doench

1 reference

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Margaret A Shipp

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3 March 2020

author name string

Bjoern Chapuy

1

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3 March 2020

Michael R McKeown

2

1 reference

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3 March 2020

Charles Y Lin

3

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3 March 2020

Margaretha G M Roemer

5

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3 March 2020

Jun Qi

6

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3 March 2020

Peter B Rahl

7

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Heather H Sun

8

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Kelly T Yeda

9

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3 March 2020

Elaine Reichert

11

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Scott J Rodig

13

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James E Bradner

16

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3 March 2020

publication date

1 December 2013

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3 March 2020

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3 March 2020

volume

24

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issue

6

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3 March 2020

page(s)

777-790

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SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas

3 March 2020

cites work

1 reference

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Transcriptional regulation and its misregulation in disease.

28 July 2018

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Targeting MYCN in neuroblastoma by BET bromodomain inhibition

28 July 2018

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Genetic heterogeneity of diffuse large B-cell lymphoma

28 July 2018

1 reference

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Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells

28 July 2018

1 reference

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Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma

28 July 2018

1 reference

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Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma.

28 July 2018

1 reference

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Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein

28 July 2018

1 reference

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BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

28 July 2018

1 reference

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Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone

28 July 2018

1 reference

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Roles of BCL6 in normal and transformed germinal center B cells

28 July 2018

1 reference

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Histone recognition and large-scale structural analysis of the human bromodomain family

28 July 2018

1 reference

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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

28 July 2018

1 reference

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Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation

28 July 2018

1 reference

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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

28 July 2018

1 reference

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Targeting MYC dependence in cancer by inhibiting BET bromodomains

28 July 2018

1 reference

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The genetic network controlling plasma cell differentiation

28 July 2018

1 reference

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BET bromodomain inhibition as a therapeutic strategy to target c-Myc

28 July 2018

1 reference

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018722

Analysis of the coding genome of diffuse large B-cell lymphoma

28 July 2018

1 reference

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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018722

Direct Interactions of OCA-B and TFII-I Regulate Immunoglobulin Heavy-Chain Gene Transcription by Facilitating Enhancer-Promoter Communication

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018722

Oncogenically active MYD88 mutations in human lymphoma

28 July 2018

1 reference

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Suppression of inflammation by a synthetic histone mimic

28 July 2018

1 reference

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Selective inhibition of BET bromodomains

28 July 2018

1 reference

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Salvage regimens with autologous transplantation for relapsed large B-cell lymphoma in the rituximab era

28 July 2018

1 reference

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BCL6 promoter interacts with far upstream sequences with greatly enhanced activating histone modifications in germinal center B cells

28 July 2018

1 reference

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28 July 2018

1 reference

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Defining mechanisms that regulate RNA polymerase II transcription in vivo

28 July 2018

1 reference

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IRF8 regulates B-cell lineage specification, commitment, and differentiation

28 July 2018

1 reference

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Germinal centres: role in B-cell physiology and malignancy

28 July 2018

1 reference

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Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression

28 July 2018

1 reference

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Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

28 July 2018

1 reference

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Pax5: the guardian of B cell identity and function

28 July 2018

1 reference

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Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.

28 July 2018

1 reference

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Brd2 is a TBP-associated protein and recruits TBP into E2F-1 transcriptional complex in response to serum stimulation

28 July 2018

1 reference

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Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A.

28 July 2018

1 reference

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The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018722

The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p

28 July 2018

1 reference

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The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

28 July 2018

1 reference

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Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B

28 July 2018

1 reference

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Activation of chromatin by acetylation of histone side chains

28 July 2018

1 reference

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MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Pr

28 July 2018

1 reference

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MYC and Aggressive B-cell Lymphomas

30 October 2018

1 reference

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E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia.

30 October 2018

1 reference

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OCA-B regulation of B-cell development and function

30 October 2018

1 reference

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Signaling network model of chromatin

30 October 2018

1 reference

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Up-regulation of BOB.1/OBF.1 expression in normal germinal center B cells and germinal center-derived lymphomas

30 October 2018

1 reference

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Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

30 October 2018

1 reference

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The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24332044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CCR.2013.11.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24332044%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24332044%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

24332044

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24332044%20AND%20SRC:MED&resulttype=core&format=json