Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells (Q33590390)

28 July 2017

title

Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells (English)

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28 July 2017

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3

Susan Gilfillan

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William Vermi

William Vermi

2

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Marina Cella

Marina Cella

4

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Marco Colonna

Marco Colonna

8

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Theresa L Murphy

5

Theresa L Murphy

1 reference

28 July 2017

6

Robert D Schreiber

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28 July 2017

7

Kenneth M Murphy

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28 July 2017

Stephen McCartney

1

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28 July 2017

language of work or name

English

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publication date

7 December 2009

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Journal of Experimental Medicine

28 July 2017

published in

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28 July 2017

volume

206

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28 July 2017

issue

13

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28 July 2017

page(s)

2967-2976

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Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.

28 July 2017

cites work

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Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

21 June 2018

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Toll-like receptor and RIG-I-like receptor signaling

21 June 2018

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Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

21 June 2018

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Cutting edge: Priming of NK cells by IL-18.

21 June 2018

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Host innate immune receptors and beyond: making sense of microbial infections

21 June 2018

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IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

21 June 2018

1 reference

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TLR3: interferon induction by double-stranded RNA including poly(I:C).

21 June 2018

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The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

21 June 2018

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Taking dendritic cells into medicine

21 June 2018

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Dendritic cells prime natural killer cells by trans-presenting interleukin 15

21 June 2018

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Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells

21 June 2018

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 June 2018

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CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

21 June 2018

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TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.

21 June 2018

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A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

21 June 2018

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A contribution of mouse dendritic cell-derived IL-2 for NK cell activation

21 June 2018

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CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells

21 June 2018

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NK cell compartments and their activation by dendritic cells

21 June 2018

1 reference

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Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells

21 June 2018

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Reciprocal activating interaction between natural killer cells and dendritic cells

21 June 2018

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 June 2018

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IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12.

21 June 2018

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Natural killer cells in antiviral defense: function and regulation by innate cytokines

21 June 2018

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The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

21 June 2018

1 reference

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CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo

21 June 2018

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

21 June 2018

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Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity.

21 June 2018

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Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

21 January 2018

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The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions.

21 January 2018

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Cutting edge: murine dendritic cells require IL-15R alpha to prime NK cells

21 January 2018

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Cutting edge: cooperation of IPS-1- and TRIF-dependent pathways in poly IC-enhanced antibody production and cytotoxic T cell responses

21 January 2018

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12 December 2020

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox

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12 December 2020

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection

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12 December 2020

Functional interactions between dendritic cells and NK cells during viral infection

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12 December 2020

APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA

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12 December 2020

IFN-alpha priming of human monocytes differentially regulates gram-positive and gram-negative bacteria-induced IL-10 release and selectively enhances IL-12p70, CD80, and MHC class I expression

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12 December 2020

Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo

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12 December 2020

The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity

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12 December 2020

Type I IFN contributes to NK cell homeostasis, activation, and antitumor function

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12 December 2020

Identifiers

DOI

10.1084/JEM.20091181

1 reference

28 July 2017

1 reference

28 July 2017

1 reference