Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites (Q33589782)

28 July 2017

title

Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites. (English)

1 reference

28 July 2017

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Sairei So

1

1 reference

28 July 2017

Anthony J Davis

series ordinal

2

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28 July 2017

David J Chen

series ordinal

3

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28 July 2017

language of work or name

English

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publication date

21 December 2009

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28 July 2017

published in

Journal of Cell Biology

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28 July 2017

volume

187

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28 July 2017

issue

7

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28 July 2017

page(s)

977-990

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Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

28 July 2017

cites work

1 reference

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Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation

21 June 2018

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MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

21 June 2018

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Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

21 June 2018

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Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin

21 June 2018

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Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

21 June 2018

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Protein phosphatase 2A is targeted to cell division control protein 6 by a calcium-binding regulatory subunit

21 June 2018

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Ku recruits XLF to DNA double-strand breaks

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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

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21 June 2018

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ATMIN defines an NBS1-independent pathway of ATM signalling

21 June 2018

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

21 June 2018

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21 June 2018

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Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

21 June 2018

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Involvement of novel autophosphorylation sites in ATM activation

21 June 2018

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21 June 2018

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gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes

21 June 2018

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MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

21 June 2018

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

21 June 2018

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

21 June 2018

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Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells

21 June 2018

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21 June 2018

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21 June 2018

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ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.

21 June 2018

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21 June 2018

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

21 June 2018

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Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

21 June 2018

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21 June 2018

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Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

21 June 2018

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Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

21 June 2018

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Requirement of the MRN complex for ATM activation by DNA damage

21 June 2018

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MDC1 is a mediator of the mammalian DNA damage checkpoint

21 June 2018

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MDC1 is required for the intra-S-phase DNA damage checkpoint

21 June 2018

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Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

21 June 2018

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806275

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806275

The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50[middle dot]hMRE11[middle dot]NBS1 complex DNA repair activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806275

Structure and function of a new phosphopeptide-binding domain containing the FHA2 of Rad53

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806275

The FHA domain is a modular phosphopeptide recognition motif.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806275

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806275

The genetic defect in ataxia-telangiectasia

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806275

Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

21 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200906064

Sub-nuclear localization of Rad51 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200906064

The ATM-mediated DNA-damage response: taking shape.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200906064

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200906064

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20026654

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200906064

1 reference

28 July 2017

1 reference

28 July 2017

1 reference