Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response (Q33576139)

28 July 2017

title

Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response (English)

1 reference

28 July 2017

Kate Petersen Shay

1

1 reference

28 July 2017

Alexander J Michels

2

1 reference

28 July 2017

Wenge Li

3

1 reference

28 July 2017

Ah-Ng Tony Kong

4

1 reference

28 July 2017

Tory M Hagen

5

1 reference

28 July 2017

language of work or name

English

0 references

publication date

13 April 2012

1 reference

Biochimica et Biophysica Acta

28 July 2017

published in

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28 July 2017

volume

1823

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28 July 2017

issue

6

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28 July 2017

page(s)

1102-1109

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describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4012555/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Transcription factor Nrf2: examination of nuclear protein levels by immunoblotting and promoter response element binding by chromatin immunoprecipitation (ChIP).

1 reference

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La autoantigen mediates oxidant induced de novo Nrf2 protein translation

21 June 2018

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KPNA6 (Importin α7)-Mediated Nuclear Import of Keap1 Represses the Nrf2-Dependent Antioxidant Response

21 June 2018

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Structure of the human mTOR complex I and its implications for rapamycin inhibition.

21 June 2018

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An internal ribosomal entry site mediates redox-sensitive translation of Nrf2.

21 June 2018

1 reference

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Activation of transcription factor Nrf2 by hepatitis C virus induces the cell-survival pathway

21 June 2018

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The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

21 June 2018

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Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity.

21 June 2018

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Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2.

21 June 2018

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Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults

21 June 2018

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Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2

21 June 2018

1 reference

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Phosphorylation of tyrosine 568 controls nuclear export of Nrf2.

21 June 2018

1 reference

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Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1

21 June 2018

1 reference

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Alpha-lipoic acid-induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells.

21 June 2018

1 reference

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Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

21 June 2018

1 reference

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Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation

21 June 2018

1 reference

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Nrf2 Possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Nuclear import and export signals in control of Nrf2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism

21 June 2018

1 reference

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An important role of Nrf2-ARE pathway in the cellular defense mechanism

21 June 2018

1 reference

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The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Nrf2 signaling in coordinated activation of antioxidant gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Internal ribosome initiation of translation and the control of cell death.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

eIF4G: a multipurpose ribosome adapter?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Nrf2 possesses a redox-sensitive nuclear exporting signal in the Neh5 transactivation domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012555

Translational control of nrf2 protein in activation of antioxidant response by oxidants

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22521877

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Was the initiation of translation in early eukaryotes IRES-driven?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22521877

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BBAMCR.2012.04.002

1 reference

28 July 2017

1 reference

28 July 2017

1 reference