Consensus protein design without phylogenetic bias (Q33569414)

28 July 2017

title

Consensus protein design without phylogenetic bias (English)

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28 July 2017

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2

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28 July 2017

4

Frances H Arnold

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28 July 2017

Christian Jäckel

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author name string

Peter Kast

series ordinal

3

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28 July 2017

Donald Hilvert

series ordinal

5

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28 July 2017

publication date

28 April 2010

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Journal of Molecular Biology

28 July 2017

published in

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28 July 2017

volume

399

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28 July 2017

issue

4

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28 July 2017

page(s)

541-546

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Inferring stabilizing mutations from protein phylogenies: application to influenza hemagglutinin

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Protein Design by Directed Evolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Minimalist active-site redesign: teaching old enzymes new tricks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Stability of biocatalysts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Relative tolerance of mesostable and thermostable protein homologs to extensive mutation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Design of Stable α-Helical Arrays from an Idealized TPR Motif

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Engineering proteins for thermostability: the use of sequence alignments versus rational design and directed evolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Searching sequence space for protein catalysts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

The design of a hyperstable mutant of the Abp1p SH3 domain by sequence alignment analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Temperature adaptation of enzymes: lessons from laboratory evolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

A small, thermostable, and monofunctional chorismate mutase from the archaeon Methanococcus jannaschii

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Additivity of mutational effects in proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Understanding the functional roles of amino acid residues in enzyme catalysis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Consensus mutagenesis reveals that non-helical regions influence thermal stability of horseradish peroxidase.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Development of a thermostable glucose dehydrogenase by a structure-guided consensus concept

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Engineered alkane-hydroxylating cytochrome P450(BM3) exhibiting nativelike catalytic properties

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Construction of stabilized proteins by combinatorial consensus mutagenesis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Beyond consensus: statistical free energies reveal hidden interactions in the design of a TPR motif

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Consensus-derived structural determinants of the ankyrin repeat motif

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Industrial biocatalysis today and tomorrow

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

From DNA sequence to improved functionality: using protein sequence comparisons to rapidly design a thermostable consensus phytase

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Beta-turn propensities as paradigms for the analysis of structural motifs to engineer protein stability

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

Sequence statistics reliably predict stabilizing mutations in a protein domain

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904866

The consensus concept for thermostability engineering of proteins: further proof of concept

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20433850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protein design by binary patterning of polar and nonpolar amino acids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20433850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Atomic structure of the buried catalytic pocket of Escherichia coli chorismate mutase

1 reference

15 December 2024

https://opencitations.net/index/api/v1/references/10.1016/J.JMB.2010.04.039

Identifiers

DOI

10.1016/J.JMB.2010.04.039

1 reference

28 July 2017

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28 July 2017

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