Mechanisms of protein kinase PKR-mediated amplification of beta interferon induction by C protein-deficient measles virus (Q33558639)

28 July 2017

title

Mechanisms of protein kinase PKR-mediated amplification of beta interferon induction by C protein-deficient measles virus (English)

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28 July 2017

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5

Roberto Cattaneo

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28 July 2017

author name string

Christopher S McAllister

1

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28 July 2017

Ann M Toth

2

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28 July 2017

Ping Zhang

3

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28 July 2017

Patricia Devaux

4

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28 July 2017

Charles E Samuel

6

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28 July 2017

publication date

1 January 2010

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28 July 2017

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28 July 2017

volume

84

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28 July 2017

issue

1

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28 July 2017

page(s)

380-386

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Protein kinase PKR-dependent activation of mitogen-activated protein kinases occurs through mitochondrial adapter IPS-1 and is antagonized by vaccinia virus E3L.

28 July 2017

cites work

1 reference

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21 June 2018

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The RNA-activated Protein Kinase Enhances the Induction of Interferon- and Apoptosis Mediated by Cytoplasmic RNA Sensors

21 June 2018

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Protein kinase PKR mediates the apoptosis induction and growth restriction phenotypes of C protein-deficient measles virus

21 June 2018

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Induction of protein kinase PKR-dependent activation of interferon regulatory factor 3 by vaccinia virus occurs through adapter IPS-1 signaling

21 June 2018

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Measles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon induction

21 June 2018

1 reference

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Inhibition of interferon induction and signaling by paramyxoviruses

21 June 2018

1 reference

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Sendai virus C protein plays a role in restricting PKR activation by limiting the generation of intracellular double-stranded RNA.

21 June 2018

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STAT2 is a primary target for measles virus V protein-mediated alpha/beta interferon signaling inhibition

21 June 2018

1 reference

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Measles virus circumvents the host interferon response by different actions of the C and V proteins.

21 June 2018

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Reprogrammed viruses as cancer therapeutics: targeted, armed and shielded

21 June 2018

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Measles--United States, January 1-April 25, 2008.

21 June 2018

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Attenuation of V- or C-defective measles viruses: infection control by the inflammatory and interferon responses of rhesus monkeys

21 June 2018

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Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kappaB kinase epsilon (IKKe)/TBK1.

21 June 2018

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Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

21 June 2018

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21 June 2018

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Structure and function of the protein kinase R.

21 June 2018

1 reference

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Loss of protein kinase PKR expression in human HeLa cells complements the vaccinia virus E3L deletion mutant phenotype by restoration of viral protein synthesis

21 June 2018

1 reference

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An Atomic Model of the Interferon-β Enhanceosome

21 June 2018

1 reference

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Protein kinase PKR plays a stimulus- and virus-dependent role in apoptotic death and virus multiplication in human cells

21 June 2018

1 reference

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Function of RIG-I-like receptors in antiviral innate immunity

21 June 2018

1 reference

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Toll-like receptors and Type I interferons

21 June 2018

1 reference

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Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response

21 June 2018

1 reference

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The C protein of wild-type measles virus has the ability to shuttle between the nucleus and the cytoplasm

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

mda-5, but not RIG-I, is a common target for paramyxovirus V proteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Translational inhibition and increased interferon induction in cells infected with C protein-deficient measles virus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Identification of naturally occurring amino acid variations that affect the ability of the measles virus C protein to regulate genome replication and transcription

21 June 2018

1 reference

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The PKR kinase promoter binds both Sp1 and Sp3, but only Sp3 functions as part of the interferon-inducible complex with ISGF-3 proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

STAT protein interference and suppression of cytokine signal transduction by measles virus V protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Measles virus suppresses interferon-alpha signaling pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Antiviral actions of interferons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Mutations in the measles virus C protein that up regulate viral RNA synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Measles virus P gene codes for two proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Measles virus editing provides an additional cysteine-rich protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Mechanism of interferon action: Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Tyrosine 110 in the measles virus phosphoprotein is required to block STAT1 phosphorylation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

Measles outbreaks in a population with declining vaccine uptake.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798421

31 October 2018

Identifiers

DOI

10.1128/JVI.02630-08

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28 July 2017

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28 July 2017

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