The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis (Q33504867)

27 July 2017

title

The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis (English)

1 reference

relapsing fever borreliosis

27 July 2017

1 reference

1 reference

4

T H Bugge

1 reference

27 July 2017

J A Gebbia

1

1 reference

27 July 2017

J C Monco

series ordinal

2

1 reference

27 July 2017

J L Degen

series ordinal

3

1 reference

27 July 2017

J L Benach

series ordinal

5

1 reference

27 July 2017

language of work or name

English

0 references

publication date

1 January 1999

1 reference

Journal of Clinical Investigation

27 July 2017

published in

1 reference

27 July 2017

volume

103

1 reference

27 July 2017

issue

1

1 reference

27 July 2017

page(s)

81-87

1 reference

Tissue plasminogen activator (tPA) increase neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

27 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Neuroborreliosis during relapsing fever: review of the clinical manifestations, pathology, and treatment of infections in humans and experimental animals.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

The Spirochete Borrelia crocidurae Causes Erythrocyte Rosetting during Relapsing Fever

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Growth and dissemination of Lewis lung carcinoma in plasminogen-deficient mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Immunologic and genetic analyses of VmpA of a neurotropic strain of Borrelia turicatae

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Plasminogen Is Required for Efficient Dissemination of B. burgdorferi in Ticks and for Enhancement of Spirochetemia in Mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

A mouse model of Borrelia meningitis after intradermal injection.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Impaired arterial neointima formation in mice with disruption of the plasminogen gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Borrelia burgdorferi induces secretion of pro-urokinase-type plasminogen activator by human monocytes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

A new Borrelia species isolated from patients with relapsing fever in Spain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Inhibition of Borrelia burgdorferi-bound fibrinolytic enzymes by alpha2-antiplasmin, PAI-1 and PAI-2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Experimental infection of the mouse brain by a relapsing fever Borrelia species: a molecular analysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Integrin alpha IIb beta 3 mediates binding of the Lyme disease agent Borrelia burgdorferi to human platelets

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Extracellular proteolysis in the adult murine brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Heritable susceptibility to severe Borrelia burgdorferi-induced arthritis is dominant and is associated with persistence of large numbers of spirochetes in tissues

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Variability of a bacterial surface protein and disease expression in a possible mouse model of systemic Lyme borreliosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Antigen diversity in the bacterium B. hermsii through "somatic" mutations in rearranged vmp genes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Borrelia burgdorferi binds plasminogen, resulting in enhanced penetration of endothelial monolayers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Binding of human plasminogen to Borrelia burgdorferi

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Expression of the macrophage-specific antigen F4/80 during differentiation of mouse bone marrow cells in culture

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Experimental Relapsing Fever Initiated by Borrelia hermsi: II. Sequential Appearance of Major Serotypes in the Rat

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Plasminogen activators, tissue degradation, and cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Antigenic variation is associated with DNA rearrangements in a relapsing fever Borrelia.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Human monocytes can produce tissue-type plasminogen activator

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Antigenic variation of a relapsing fever Borrelia species

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Lyme borreliosis in the severe combined immunodeficiency (scid) mouse manifests predominantly in the joints, heart, and liver

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Kinetics of Borrelia burgdorferi dissemination and evolution of disease after intradermal inoculation of mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

The plasminogen activator/plasmin system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

A surface protease and the invasive character of plague

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Tissue-type plasminogen activator-mediated activation of plasminogen on the surface of group A, C, and G streptococci

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Borrelia burgdorferiAdherence and Injury to Undifferentiated and Differentiated Neural Cells In Vitro

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Adherence of the Lyme disease spirochete to glial cells and cells of glial origin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Neuronal Death in the Hippocampus Is Promoted by Plasmin-Catalyzed Degradation of Laminin

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Vascular clearance of Borrelia burgdorferi in rats

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Concomitant secretion of prourokinase and of a plasminogen activator-specific inhibitor by cultured human monocytes-macrophages

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Borrelia burgdorferi in the central nervous system: experimental and clinical evidence for early invasion

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction

31 October 2018

1 reference

12 December 2020

Binding of human plasminogen and urokinase-type plasminogen activator to the Lyme disease spirochete, Borrelia burgdorferi

1 reference

12 December 2020

Impaired wound healing in mice with a disrupted plasminogen gene

1 reference

12 December 2020

Plasminogen activation by invasive human pathogens

1 reference

12 December 2020

An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus

1 reference

12 December 2020

Healing of corneal epithelial defects in plasminogen- and fibrinogen-deficient mice

1 reference

12 December 2020

Borrelia burgdorferi and other related spirochetes bind to galactocerebroside

1 reference

12 December 2020

Streptokinase-producing streptococci grown in human plasma acquire unregulated cell-associated plasmin activity

1 reference

12 December 2020

Mechanism of activation of human plasminogen by streptokinase. Presence of active center in streptokinase-plasminogen complex

1 reference

12 December 2020

Lyme neuroborreliosis

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI5171

1 reference

27 July 2017

1 reference

27 July 2017

1 reference