Broad neutralization of human immunodeficiency virus type 1 (HIV-1) elicited from human rhinoviruses that display the HIV-1 gp41 ELDKWA epitope (Q33417195)

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English	Broad neutralization of human immunodeficiency virus type 1 (HIV-1) elicited from human rhinoviruses that display the HIV-1 gp41 ELDKWA epitope	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 July 2017

Broad neutralization of human immunodeficiency virus type 1 (HIV-1) elicited from human rhinoviruses that display the HIV-1 gp41 ELDKWA epitope (English)

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Europe PubMed Central

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26 July 2017

Gail Ferstandig Arnold

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Gail Ferstandig Arnold

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Christos J Petropoulos

11

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Christos J Petropoulos

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Europe PubMed Central

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26 July 2017

14

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Eddy Arnold

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26 July 2017

Hermann Katinger

13

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Hermann Katinger

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26 July 2017

author name string

Paola K Velasco

2

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Europe PubMed Central

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26 July 2017

Andrew K Holmes

3

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Europe PubMed Central

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26 July 2017

Terri Wrin

4

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Europe PubMed Central

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26 July 2017

Sheila C Geisler

5

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Europe PubMed Central

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26 July 2017

Pham Phung

6

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26 July 2017

Yu Tian

7

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26 July 2017

Dawn A Resnick

8

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Europe PubMed Central

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26 July 2017

Xuejun Ma

9

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Europe PubMed Central

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26 July 2017

Thomas M Mariano

10

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Europe PubMed Central

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26 July 2017

John W Taylor

12

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Europe PubMed Central

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26 July 2017

publication date

11 March 2009

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26 July 2017

number of pages

14

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Journal of Virology

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26 July 2017

83

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26 July 2017

10

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26 July 2017

5087-5100

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Europe PubMed Central

PubMed publication ID

26 July 2017

Lipid binding properties of 4E10, 2F5, and WR304 monoclonal antibodies that neutralize HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

14 July 2018

Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

14 July 2018

The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design

1 reference

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14 July 2018

The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.

1 reference

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14 July 2018

Not just sheer luck! Immune correlates of protection against HIV-1 infection.

1 reference

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14 July 2018

Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles

1 reference

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14 July 2018

Reassessment of autoreactivity of the broadly neutralizing HIV antibodies 4E10 and 2F5 and retrospective analysis of clinical safety data

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14 July 2018

Assessment of antibody responses against gp41 in HIV-1-infected patients using soluble gp41 fusion proteins and peptides derived from M group consensus envelope

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In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10.

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Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection

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14 July 2018

Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy

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14 July 2018

Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion state

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Immunogenicity of a chimeric hepatitis A virus (HAV) carrying the HIV gp41 epitope 2F5.

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Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responses

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Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma

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Characterization and HIV-1 fusion inhibitory properties of monoclonal Fabs obtained from a human non-immune phage library selected against diverse epitopes of the ectodomain of HIV-1 gp41.

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14 July 2018

The 2F5 epitope is helical in the HIV-1 entry inhibitor T-20.

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14 July 2018

Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

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Protection of rhesus monkeys against infection with minimally pathogenic simian-human immunodeficiency virus: correlations with neutralizing antibodies and cytotoxic T cells

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14 July 2018

Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1.

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14 July 2018

Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

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14 July 2018

A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs.

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Induction of mucosal and systemic neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1) by oral immunization with bovine Papillomavirus-HIV-1 gp41 chimeric virus-like particles

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The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection

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14 July 2018

Progress towards the development of a HIV-1 gp41-directed vaccine

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14 July 2018

Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion

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14 July 2018

Antibody neutralization and escape by HIV-1

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14 July 2018

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

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14 July 2018

A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41

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14 July 2018

A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.

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Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women.

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Chimeric plant virus particles as immunogens for inducing murine and human immune responses against human immunodeficiency virus type 1.

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Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro

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Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein

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Epitope insertion into variable loops of HIV-1 gp120 as a potential means to improve immunogenicity of viral envelope protein

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Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion.

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Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies.

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A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity.

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Human rhinovirus type 14:human immunodeficiency virus type 1 (HIV-1) V3 loop chimeras from a combinatorial library induce potent neutralizing antibody responses against HIV-1.

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Atomic structure of a thermostable subdomain of HIV-1 gp41

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Potent and synergistic neutralization of human immunodeficiency virus (HIV) type 1 primary isolates by hyperimmune anti-HIV immunoglobulin combined with monoclonal antibodies 2F5 and 2G12

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Atomic structure of the ectodomain from HIV-1 gp41

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Core structure of gp41 from the HIV envelope glycoprotein

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Length polymorphism within the second variable region of the human immunodeficiency virus type 1 envelope glycoprotein affects accessibility of the receptor binding site

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Immunogenic presentation of a conserved gp41 epitope of human immunodeficiency virus type 1 on recombinant surface antigen of hepatitis B virus.

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Chimeras from a human rhinovirus 14-human immunodeficiency virus type 1 (HIV-1) V3 loop seroprevalence library induce neutralizing responses against HIV-1.

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14 July 2018

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

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Generation of Human Monoclonal Antibodies against HIV-1 Proteins; Electrofusion and Epstein-Barr Virus Transformation for Peripheral Blood Lymphocyte Immortalization

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Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS.

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14 July 2018

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31 October 2018

The membrane-proximal external region of HIV-1 gp41: a vaccine target worth exploring

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31 October 2018

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31 October 2018

Trimeric membrane-anchored gp41 inhibits HIV membrane fusion.

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31 October 2018

Synthesis, conformation, and immunogenicity of monosaccharide-centered multivalent HIV-1 gp41 peptides containing the sequence of DP178.

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31 October 2018

Enhancement of alpha -helicity in the HIV-1 inhibitory peptide DP178 leads to an increased affinity for human monoclonal antibody 2F5 but does not elicit neutralizing responses in vitro. Implications for vaccine design

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31 October 2018

HIV-1 gp41 envelope residues 650-685 exposed on native virus act as a lectin to bind epithelial cell galactosyl ceramide

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31 October 2018

Construction of recombinant targeting immunogens incorporating an HIV-1 neutralizing epitope into sites of differing conformational constraint

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31 October 2018

Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1.

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31 October 2018

gp120: Biologic aspects of structural features

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31 October 2018

Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection

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31 October 2018

HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers

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31 October 2018

Epidemiologic and biologic characterization of a cohort of human immunodeficiency virus type 1 highly exposed, persistently seronegative female sex workers in northern Thailand. Chiang Mai HEPS Working Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

31 October 2018

Broad cross-neutralizing activity in serum is associated with slow progression and low risk of transmission in primate lentivirus infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

31 October 2018

Mother-to-child transmission of human immunodeficiency virus type 1: correlation with neutralizing antibodies against primary isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

31 October 2018

Studies in subjects with long-term nonprogressive human immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

31 October 2018

Neutralization of primary HIV-1 isolates by anti-envelope monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

31 October 2018

Antibodies to conserved epitopes of the HIV-1 envelope in sera from long-term non-progressors: prevalence and association with neutralizing activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

31 October 2018

Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

31 October 2018

Predefined spacers between epitopes on a recombinant epitope-peptide impacted epitope-specific antibody response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682058

31 October 2018

Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and construction of rhinovirus chimeras incorporating immunogens from polio, influenza, and human immunodeficiency viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunodominant glycoprotein 41 epitope identified by seroreactivity in HIV type 1-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 antibody--debris or virion?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational constraints imposed on a pan-neutralizing HIV-1 antibody epitope result in increased antigenicity but not neutralizing response

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 vaccine development: constrained peptide immunogens show improved binding to the anti-HIV-1 gp41 MAb

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of antibody reactivity to ELDKWA, a glycoprotein 41 neutralization epitope, with disease progression in children perinatally infected with HIV type 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19279101

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00184-09

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

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