Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells (Q33415997)

26 July 2017

title

Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells (English)

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26 July 2017

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1 reference

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Matthew E Gegg

1

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Anthony H V Schapira

series ordinal

3

object named as

Anthony H V Schapira

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26 July 2017

4

Jan-Willem Taanman

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26 July 2017

2

J Mark Cooper

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26 July 2017

language of work or name

English

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publication date

9 March 2009

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26 July 2017

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26 July 2017

volume

4

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26 July 2017

issue

3

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26 July 2017

page(s)

e4756

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Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

9 March 2009

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo

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Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

21 June 2018

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PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons

21 June 2018

1 reference

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The PINK1/Parkin pathway regulates mitochondrial morphology

21 June 2018

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21 June 2018

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Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1.

21 June 2018

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Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

21 June 2018

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The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

21 June 2018

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Cell cycle- and ribonucleotide reductase-driven changes in mtDNA copy number influence mtDNA Inheritance without compromising mitochondrial gene expression

21 June 2018

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PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c.

21 June 2018

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PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

21 June 2018

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Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

21 June 2018

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Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

21 June 2018

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Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6.

21 June 2018

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C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.

21 June 2018

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Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

21 June 2018

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Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

21 June 2018

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PINK1 protein in normal human brain and Parkinson's disease

21 June 2018

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Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

21 June 2018

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 June 2018

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

21 June 2018

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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

21 June 2018

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Expanding insights of mitochondrial dysfunction in Parkinson's disease.

21 June 2018

1 reference

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Parkin enhances mitochondrial biogenesis in proliferating cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Simultaneous detection and quantification of mitochondrial DNA deletion(s), depletion, and over-replication in patients with mitochondrial disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Mitochondrial AKAP121 links cAMP and src signaling to oxidative metabolism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Mitochondrial threshold effects.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Release of replication termination controls mitochondrial DNA copy number after depletion with 2',3'-dideoxycytidine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Modulation of mitochondrial transcription in response to mtDNA depletion and repletion in HeLa cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

cAMP-dependent phosphorylation of the nuclear encoded 18-kDa (IP) subunit of respiratory complex I and activation of the complex in serum-starved mouse fibroblast cultures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Preparation and properties of mitochondria derived from synaptosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004756

Determination of glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) activity by high-performance liquid chromatography and electrochemical detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004756

Retrospective, multicentric study of 180 children with cytochrome C oxidase deficiency.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004756

Cell cycle dependent morphology changes and associated mitochondrial DNA redistribution in mitochondria of human cell lines.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004756

Early-onset familial parkinsonism due to POLG mutations

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004756

Analysis of the trinucleotide CAG repeat from the DNA polymerase gamma gene (POLG) in patients with Parkinson's disease.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004756

Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004756

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Mitochondrial DNA impacts the morphology of mitochondrial compartments

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2649444

Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture

31 October 2018

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12 December 2020

Coexistence of mutations in PINK1 and mitochondrial DNA in early onset parkinsonism

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12 December 2020

Mitochondrial DNA Depletion and Thymidine Phosphate Pool Dynamics in a Cellular Model of Mitochondrial Neurogastrointestinal Encephalomyopathy

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12 December 2020

Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease

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12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

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12 December 2020

10.1371/JOURNAL.PONE.0004756

Identifiers

DOI

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26 July 2017

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26 July 2017

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