Phase II Study of Dasatinib in Relapsed or Refractory Chronic Lymphocytic Leukemia (Q33394487)

26 July 2017

title

Phase II study of dasatinib in relapsed or refractory chronic lymphocytic leukemia (English)

1 reference

26 July 2017

Phase II Study of Dasatinib in Relapsed or Refractory Chronic Lymphocytic Leukemia (English)

1 reference

Crossref

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2879

27 November 2024

0 references

1 reference

dasatinib monohydrate

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chronic lymphocytic leukemia

inferred from title

1 reference

1 reference

antineoplastic resistance

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

8

Ann S Lacasce

1 reference

26 July 2017

13

Donna Neuberg

1 reference

26 July 2017

Tak Takvorian

3

1 reference

26 July 2017

Philippe Armand

10

1 reference

26 July 2017

Lillian Werner

12

1 reference

26 July 2017

Philip C. Amrein

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

Eyal C. Attar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

Ephraim P. Hochberg

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

Karen K. Ballen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

Kathleen M. Leahy

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

David C. Fisher

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

Ann S. Lacasce

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

Eric D. Jacobsen

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

Robert P. Hasserjian

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

Jennifer R. Brown

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

27 November 2024

language of work or name

English

0 references

publication date

14 March 2011

1 reference

full work available at URL

26 July 2017

https://aacrjournals.org/clincancerres/article-pdf/17/9/2977/2003629/2977.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

https://europepmc.org/articles/PMC3108904

27 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

https://europepmc.org/articles/PMC3108904?pdf=render

27 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

https://doi.org/10.1158/1078-0432.ccr-10-2879

27 November 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21402714

https://aacrjournals.org/clincancerres/article-pdf/17/9/2977/2003629/2977.pdf

27 November 2024

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2879

27 November 2024

published in

Clinical Cancer Research

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26 July 2017

volume

17

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26 July 2017

issue

9

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26 July 2017

page(s)

2977-2986

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Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

26 July 2017

cites work

1 reference

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Phase 3 study of dasatinib 140 mg once daily versus 70 mg twice daily in patients with chronic myeloid leukemia in accelerated phase resistant or intolerant to imatinib: 15-month median follow-up

21 June 2018

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Crystal structures of the Lyn protein tyrosine kinase domain in its Apo- and inhibitor-bound state

21 June 2018

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The GNAS1 T393C polymorphism and lack of clinical prognostic value in chronic lymphocytic leukemia

21 June 2018

1 reference

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The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

21 June 2018

1 reference

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Chronic lymphocytic leukemia

21 June 2018

1 reference

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CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function

21 June 2018

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Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

21 June 2018

1 reference

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Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.

21 June 2018

1 reference

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Overriding imatinib resistance with a novel ABL kinase inhibitor

21 June 2018

1 reference

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NF- kappa B2/p100 induces Bcl-2 expression

21 June 2018

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CDNA microarray gene expression analysis of B-cell chronic lymphocytic leukemia proposes potential new prognostic markers involved in lymphocyte trafficking

21 June 2018

1 reference

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National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment

21 June 2018

1 reference

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Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108904

Activities of SYK and PLCgamma2 predict apoptotic response of CLL cells to SRC tyrosine kinase inhibitor dasatinib.

21 June 2018

1 reference

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Phase I study of the effect of gastric acid pH modulators on the bioavailability of oral dasatinib in healthy subjects.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108904

Dasatinib induces a response in chronic lymphocytic leukemia.

31 October 2018

1 reference

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c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches

31 October 2018

1 reference

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The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes

31 October 2018

1 reference

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The effect of FK506 on transforming growth factor beta signaling and apoptosis in chronic lymphocytic leukemia B cells

31 October 2018

1 reference

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The GNAS1 T393C polymorphism is associated with disease progression and survival in chronic lymphocytic leukemia

31 October 2018

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Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia

31 October 2018

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Results of first salvage therapy for patients refractory to a fludarabine regimen in chronic lymphocytic leukemia

31 October 2018

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Frequency and type of serious infections in fludarabine-refractory B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma: implications for clinical trials in this patient population

31 October 2018

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B-Cell Receptor Translocation to Lipid Rafts and Associated Signaling Differ between Prognostically Important Subgroups of Chronic Lymphocytic Leukemia

31 October 2018

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Dasatinib sensitizes primary chronic lymphocytic leukaemia lymphocytes to chlorambucil and fludarabinein vitro

31 October 2018

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Clinical trials referral resource. Clinical trials with perillyl alcohol

10 December 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21402714

12 December 2020

inferred from PubMed ID database lookup

Pseudohyperkalemia in chronic lymphocytic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21402714

12 December 2020

inferred from PubMed ID database lookup

Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21402714

12 December 2020

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The SRC/ABL Inhibitor BMS-354825 Overcomes Resistance to Imatinib Mesylate in Chronic Myelogenous Leukemia Cells through Multiple Mechanisms.

13

1 reference

Crossref

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2879

Hematologic and Cytogenetic Responses in Imatinib-Resistant Accelerated and Blast Phase Chronic Myeloid Leukemia (CML) Patients Treated with the Dual SRC/ABL Kinase Inhibitor BMS-354825: Results from a Phase I Dose Escalation Study.

27 November 2024

14

1 reference

Crossref

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2879

27 November 2024

Identifiers

1 reference

26 July 2017

1 reference

26 July 2017

1 reference