Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders (Q33374851)

26 July 2017

title

Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders (English)

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26 July 2017

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John D Crispino

7

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Michelle M Le Beau

8

object named as

Michelle M Le Beau

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26 July 2017

John M Joslin

1

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26 July 2017

Anthony A Fernald

2

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26 July 2017

Thelma R Tennant

3

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26 July 2017

Elizabeth M Davis

4

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26 July 2017

Scott C Kogan

5

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26 July 2017

John Anastasi

6

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26 July 2017

language of work or name

English

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publication date

9 April 2007

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26 July 2017

number of pages

8

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inferred from page(s)

published in

Blood

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26 July 2017

volume

110

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26 July 2017

issue

2

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26 July 2017

page(s)

719-726

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Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-Ras

26 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

A gene-driven ENU-based approach to generating an allelic series in any gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series.

14 July 2018

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Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

14 July 2018

1 reference

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AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

14 July 2018

1 reference

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Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Suppression of growth and transformation and induction of apoptosis by EGR-1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Therapy-related myeloid leukemia

14 July 2018

1 reference

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UV activates growth factor receptors via reactive oxygen intermediates

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Further studies on chromosome 15 trisomy in murine T-cell lymphomas: mapping of the relevant chromosome segment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Multilineage transcriptional priming and determination of alternate hematopoietic cell fates

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Mutations of genes in the receptor tyrosine kinase (RTK)/RAS-BRAF signal transduction pathway in therapy-related myelodysplasia and acute myeloid leukemia

31 October 2018

1 reference

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Genetic susceptibility to thymic lymphomas and K-ras gene mutation in mice after exposure to X-rays and N-ethyl-N-nitrosourea

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924479

N-ras mutations in radiation-induced murine leukemic cells

31 October 2018

1 reference

12 December 2020

An E mu-BCL-2 transgene facilitates leukaemogenesis by ionizing radiation

1 reference

12 December 2020

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

12 December 2020

EGR1 predicts PTEN and survival in patients with non-small-cell lung cancer

1 reference

12 December 2020

Early growth response gene 1 (EGR1) is deleted in estrogen receptor-negative human breast carcinoma

1 reference

12 December 2020

Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor progno

1 reference

12 December 2020

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice

1 reference

12 December 2020

Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-A

1 reference

12 December 2020

dic(5;17): A recurring abnormality in malignant myeloid disorders associated with mutations ofTP53

1 reference

12 December 2020

10.1182/BLOOD-2007-01-068809

Identifiers

DOI

1 reference

release_fiz6rws3rbfv5k3ddrbjoxjhi4

26 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/fiz6rws3rbfv5k3ddrbjoxjhi4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1924479

1 reference

26 July 2017

1 reference