Production of soluble and active transferrin receptor-targeting single-chain antibody using Saccharomyces cerevisiae (Q33237134)

24 July 2017

title

Production of soluble and active transferrin receptor-targeting single-chain antibody using Saccharomyces cerevisiae (English)

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24 July 2017

main subject

Saccharomyces cerevisiae

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Benjamin J Hackel

1

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24 July 2017

Dagang Huang

2

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24 July 2017

Jennifer C Bubolz

3

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24 July 2017

Xin X Wang

4

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24 July 2017

Eric V Shusta

5

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24 July 2017

publication date

25 March 2006

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24 July 2017

published in

Pharmaceutical Research

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24 July 2017

volume

23

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24 July 2017

issue

4

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24 July 2017

page(s)

790-797

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Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system

24 July 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-9778-7

The yeast EUG1 gene encodes an endoplasmic reticulum protein that is functionally related to protein disulfide isomerase

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS11095-006-9778-7

Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library

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Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier

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Reduction of BiP levels decreases heterologous protein secretion in Saccharomyces cerevisiae.

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

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Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies.

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Selection of tumor-specific internalizing human antibodies from phage libraries

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Human blood-brain barrier insulin receptor

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Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells

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Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.

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Cloning and expression in Pichia pastoris of a genetically engineered single chain antibody against the rat transferrin receptor

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12 December 2020

An integrating vector for tunable, high copy, stable integration into the dispersed Ty delta sites of Saccharomyces cerevisiae

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12 December 2020

Co-expression of molecular chaperones does not improve the heterologous expression of mammalian G-protein coupled receptor expression in yeast

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Protein Disulfide Isomerase and Assisted Protein Folding

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Secretion of human epidermal growth factor from Saccharomyces cerevisiae using synthetic leader sequences.

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Synthesis of pegylated immunonanoparticles

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Brain-specific expression of an exogenous gene after i.v. administration

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Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector

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Global non-viral gene transfer to the primate brain following intravenous administration

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12 December 2020

Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae

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12 December 2020

Endocytosis and transcytosis of an immunoliposome-based brain drug delivery system

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12 December 2020

The essential function of protein-disulfide isomerase is to unscramble non-native disulfide bonds.

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Drug efflux transporters in the CNS.

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Secretion and surface display of green fluorescent protein using the yeast Saccharomyces cerevisiae

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High level Escherichia coli expression and production of a bivalent humanized antibody fragment

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12 December 2020

Quality control in the secretory pathway

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12 December 2020

Receptor-mediated transcytosis of transferrin across the blood-brain barrier

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12 December 2020

Blood-brain barrier penetration and in vivo activity of an NGF conjugate

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12 December 2020

Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments

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12 December 2020

Genetically engineered brain drug delivery vectors: cloning, expression and in vivo application of an anti-transferrin receptor single chain antibody-streptavidin fusion gene and protein

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12 December 2020

Association of transport-defective light chains with immunoglobulin heavy chain binding protein

1 reference

12 December 2020

10.1007/S11095-006-9778-7

Identifiers

DOI

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24 July 2017

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