Drug discovery by dynamic combinatorial libraries (Q31096767)

28 June 2017

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title

Drug discovery by dynamic combinatorial libraries (English)

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28 June 2017

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2

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Olof Ramström

series ordinal

1

object named as

Olof Ramström

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28 June 2017

publication date

1 January 2002

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Nature Reviews Drug Discovery

28 June 2017

published in

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28 June 2017

volume

1

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28 June 2017

issue

1

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28 June 2017

page(s)

26-36

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Strategies for the Dynamic Integration of Combinatorial Synthesis and Screening

28 June 2017

cites work

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Dynamic diversity and small-molecule evolution: a new paradigm for ligand identification

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Molecular evolution: dynamic combinatorial libraries, autocatalytic networks and the quest for molecular function

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Dynamic combinatorial chemistry

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Einfluss der Configuration auf die Wirkung der Enzyme

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Virtual combinatorial libraries: dynamic generation of molecular and supramolecular diversity by self-assembly

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Self-Assembly of a Circular Double Helicate

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Template-Directed Self-Recognition of Alkyl-Bridged Bis(catechol) Ligands in the Formation of Helicate-Type Complexes.

31 March 2020

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Adaptive self-assembly: environment-induced formation and reversible switching of polynuclear metallocyclophanes

31 March 2020

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Dynamic assembly of coordination boxes from (en)Pd(II) unit and a rectangular panel-like ligand: NMR, CSI-MS, and X-ray studies

31 March 2020

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Guest-Templated Selection and Amplification of a Receptor by Noncovalent Combinatorial Synthesis

31 March 2020

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Selection of DNA-binding compounds via multistage molecular evolution

31 March 2020

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Dynamic hemicarcerands and hemicarceplexes

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Double-level "orthogonal" dynamic combinatorial libraries on transition metal template

31 March 2020

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Identification and Isolation of a Receptor for N-Methyl Alkylammonium Salts: Molecular Amplification in a Pseudo-peptide Dynamic Combinatorial Library

31 March 2020

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Chloroform-soluble schiff-base Zn(II) or Cd(II) complexes from a dynamic combinatorial library

31 March 2020

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Organic “Magic Rings”: The Hydrogen Bond-Directed Assembly of Catenanes under Thermodynamic Control

31 March 2020

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Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria

31 March 2020

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Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface

31 March 2020

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In situ generation and screening of a dynamic combinatorial carbohydrate library against concanavalin A.

31 March 2020

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Template-induced and molecular recognition directed hierarchical generation of supramolecular assemblies from molecular strands

31 March 2020

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"Masterpiece" copolymer sequences by targeted equilibrium-shifting

31 March 2020

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Self-recognition in helicate self-assembly: spontaneous formation of helical metal complexes from mixtures of ligands and metal ions

31 March 2020

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Nonspecific protease-catalyzed hydrolysis/synthesis of a mixture of peptides: product diversity and ligand amplification by a molecular trap

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Guest-induced reorganization of a self-assembled Pd(II) complex

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Impact of mass spectrometry on combinatorial chemistry

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31 March 2020

Identifiers

DOI

10.1038/NRD704

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Dimensions Publication ID

28 June 2017

1008849589

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