Mitochondrial dysfunction as the molecular basis of bipolar disorder: therapeutic implications. (Q31088436)

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23 December 2019

review article

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title

Mitochondrial dysfunction as the molecular basis of bipolar disorder: therapeutic implications (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17190525%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17190525%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

author name string

Tadafumi Kato

series ordinal

1

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28 June 2017

publication date

1 January 2007

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23 December 2019

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23 December 2019

volume

21

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23 December 2019

issue

1

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23 December 2019

page(s)

1-11

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Magnetic resonance spectroscopy in affective disorders

23 December 2019

cites work

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Axonal sprouting of noradrenergic locus coeruleus neurons following repeated stress and antidepressant treatment

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Brain metabolic alterations in medication-free patients with bipolar disorder

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Decreased brain intracellular pH measured by 31P-MRS in bipolar disorder: a confirmation in drug-free patients and correlation with white matter hyperintensity

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Mitochondrial inheritance in depression, dysmotility and migraine?

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Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments

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Molecular evidence for mitochondrial dysfunction in bipolar disorder

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The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia

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Regulation of ER stress proteins by valproate: therapeutic implications.

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The possible association between affective disorder and partially deleted mitochondrial DNA.

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Lithium- and valproate-induced alterations in circadian locomotor behavior in Drosophila

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The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

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Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions

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12 December 2020

Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling

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12 December 2020

Treatment of rapidly cycling bipolar patient by using extended bed rest and darkness to stabilize the timing and duration of sleep.

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12 December 2020

Human mitochondrial DNA with large deletions repopulates organelles faster than full-length genomes under relaxed copy number control

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Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain

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12 December 2020

Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

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12 December 2020

In vivo 31P NMR spectroscopy of agonist-stimulated phosphatidylinositol metabolism in cat brain

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12 December 2020

Mitochondrial DNA 3644T-->C mutation associated with bipolar disorder

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12 December 2020

Randomized, placebo-controlled trial of olanzapine as maintenance therapy in patients with bipolar I disorder responding to acute treatment with olanzapine

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12 December 2020

Impaired behavioral suppression by light in metabotropic glutamate receptor subtype 6-deficient mice

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Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice

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Autosomal dominant external ophthalmoplegia and bipolar affective disorder associated with a mutation in the ANT1 gene.

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12 December 2020

Impaired masking responses to light in melanopsin-knockout mice

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Mitochondrial dysfunction in bipolar disorder

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12 December 2020

Mitochondrial DNA 3243A>G mutation and increased expression of LARS2 gene in the brains of patients with bipolar disorder and schizophrenia.

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12 December 2020

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

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12 December 2020

Association of bipolar disorder with the 5178 polymorphism in mitochondrial DNA

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12 December 2020

Measurement of brain phosphoinositide metabolism in bipolar patients using in vivo 31P-MRS

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12 December 2020

Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study.

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12 December 2020

Association of mitochondrial complex I subunit gene NDUFV2 at 18p11 with bipolar disorder in Japanese and the National Institute of Mental Health pedigrees.

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12 December 2020

The other, forgotten genome: mitochondrial DNA and mental disorders

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12 December 2020

Quantitative analysis of leukocyte mitochondrial DNA deletion in affective disorders

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12 December 2020

Mitochondrial DNA Sequence Diversity in Bipolar Affective Disorder

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12 December 2020

A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Divalproex Maintenance Study Group

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12 December 2020

Quantitative analysis of mitochondrial DNA deletions in the brains of patients with bipolar disorder and schizophrenia.

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12 December 2020

Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

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12 December 2020

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder

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12 December 2020

The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials

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12 December 2020

Downregulation in components of the mitochondrial electron transport chain in the postmortem frontal cortex of subjects with bipolar disorder.

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12 December 2020

Rapid Mood Swings After Unmonitored Light Exposure

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12 December 2020

Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis

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12 December 2020

Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research

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12 December 2020

Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia

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12 December 2020

Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions

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12 December 2020

Oral uridine pro-drug PN401 decreases neurodegeneration, behavioral impairment, weight loss and mortality in the 3-nitropropionic acid mitochondrial toxin model of Huntington's disease

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12 December 2020

Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes

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12 December 2020

Long-term lithium therapy for bipolar disorder: systematic review and meta-analysis of randomized controlled trials

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12 December 2020

Increased levels of a mitochondrial DNA deletion in the brain of patients with bipolar disorder

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12 December 2020

Neuroprotective effects of oral administration of triacetyluridine against MPTP neurotoxicity

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12 December 2020

A speculative model of affective illness cyclicity based on patterns of drug tolerance observed in amygdala-kindled seizures

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12 December 2020

Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy

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12 December 2020

Expression of mitochondria-related genes in lymphoblastoid cells from patients with bipolar disorder

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12 December 2020

Dextro-amphetamine increases phosphoinositol cycle activity in volunteers: an MRS study

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12 December 2020

Mitochondrial complex I subunits expression is altered in schizophrenia: a postmortem study

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12 December 2020

Neuroanatomical abnormalities as risk factors for bipolar disorder

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12 December 2020

Comprehensive expression analysis of a rat depression model

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12 December 2020

Multiple deletions of mitochondrial DNA in several tissues of a patient with severe retarded depression and familial progressive external ophthalmoplegia

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12 December 2020

Deletion of leukocyte mitochondrial DNA in bipolar disorder

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12 December 2020

New approaches to modeling bipolar disorder

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12 December 2020

Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: further support for the involvement of mitochondrial function in anxiety disorders

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12 December 2020

Psychiatric endophenotypes and the development of valid animal models.

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12 December 2020

Replication of mitochondrial DNA occurs throughout the mitochondria of cultured human cells

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12 December 2020

POLG mutations in sporadic mitochondrial disorders with multiple mtDNA deletions

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12 December 2020

Antidepressant-like effects of uridine and omega-3 fatty acids are potentiated by combined treatment in rats

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12 December 2020

Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes

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12 December 2020

Genetics of bipolar disorder

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12 December 2020

Lateralized abnormality of high energy phosphate metabolism in the frontal lobes of patients with bipolar disorder detected by phase-encoded 31P-MRS

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12 December 2020

Alterations in brain phosphorous metabolism in bipolar disorder detected by in vivo 31P and 7Li magnetic resonance spectroscopy

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12 December 2020

Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics

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12 December 2020

Mitochondrial DNA mutations, apoptosis, and the misfolded protein response.

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12 December 2020

New insights help define the pathophysiology of bipolar affective disorder: neuroimaging and neuropathology findings

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12 December 2020

Review of the literature on major mental disorders in adult patients with mitochondrial diseases

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12 December 2020

A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder

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12 December 2020

Manic-depressive patients may be supersensitive to light

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12 December 2020

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12 December 2020

Impairments of neuroplasticity and cellular resilience in severe mood disorders: implications for the development of novel therapeutics

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12 December 2020

Mitochondrial genetic analyses suggest selection against maternal lineages in bipolar affective disorder

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12 December 2020

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12 December 2020

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12 December 2020

Endophenotypes in bipolar disorder

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12 December 2020

Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress

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12 December 2020

Perspectives for the development of animal models of bipolar disorder

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12 December 2020

Mitochondrial DNA sequence analysis of patients with 'atypical psychosis'.

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12 December 2020

Mitochondrial DNA polymorphisms in bipolar disorder

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12 December 2020

Dark therapy for mania: a pilot study

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12 December 2020

New insights into the central PACAPergic system from the phenotypes in PACAP- and PACAP receptor-knockout mice

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12 December 2020

Intracellular calcium signaling systems in the pathophysiology of affective disorders.

1 reference

12 December 2020

The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers

1 reference

12 December 2020

Identification of mitochondrial DNA polymorphisms that alter mitochondrial matrix pH and intracellular calcium dynamics

1 reference

12 December 2020

Genome-wide expression analysis detects eight genes with robust alterations specific to bipolar I disorder: relevance to neuronal network perturbation

1 reference

12 December 2020

Apoptotic mechanisms and the synaptic pathology of schizophrenia

1 reference

12 December 2020