From big data analysis to personalized medicine for all: challenges and opportunities (Q30976798)

29 October 2017

2 references

25 June 2019

14 November 2020

From big data analysis to personalized medicine for all: challenges and opportunities (English)

1 reference

29 October 2017

0 references

0 references

1 reference

14 November 2020

personalized medicine

1 reference

3

David Meyre

1 reference

29 October 2017

Akram Alyass

1

1 reference

29 October 2017

Michelle Turcotte

series ordinal

2

1 reference

29 October 2017

27 June 2015

3 references

29 October 2017

25 June 2019

14 November 2020

3 references

29 October 2017

25 June 2019

14 November 2020

8

1 reference

29 October 2017

33

1 reference

Creative Commons Attribution

29 October 2017

2 references

25 June 2019

14 November 2020

0 references

describes a project that uses

MUMmer

object named as

MUMmer

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

Cytoscape

object named as

CytoScape

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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Jumping on the Train of Personalized Medicine: A Primer for Non- Geneticist Clinicians: Part 3. Clinical Applications in the Personalized Medicine Area

14 July 2018

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Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 2. Fundamental Concepts in Genetic Epidemiology

14 July 2018

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Network medicine analysis of COPD multimorbidities

14 July 2018

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A critical reanalysis of the relationship between genomics and well-being

14 July 2018

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Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 1. Fundamental Concepts in Molecular Genetics

14 July 2018

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MODMatcher: multi-omics data matcher for integrative genomic analysis

14 July 2018

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Integrative omics analysis. A study based on Plasmodium falciparum mRNA and protein data

14 July 2018

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Use of prior knowledge for the analysis of high-throughput transcriptomics and metabolomics data

14 July 2018

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Data integration in the era of omics: current and future challenges

14 July 2018

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Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD

14 July 2018

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Translating biotechnology to knowledge-based innovation, peace, and development? Deploy a Science Peace Corps--an open letter to world leaders

14 July 2018

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A multivariate approach to the integration of multi-omics datasets

14 July 2018

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All the post-genomic world is a stage: the actors and narrators required for translating pharmacogenomics into public health

14 July 2018

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Principles and methods of integrative genomic analyses in cancer

14 July 2018

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Joint modeling of imaging and genetics

14 July 2018

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P4 medicine needs P4 education.

14 July 2018

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Bionimbus: a cloud for managing, analyzing and sharing large genomics datasets

14 July 2018

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Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses

14 July 2018

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CGtag: complete genomics toolkit and annotation in a cloud-based Galaxy

14 July 2018

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Metadata checklist for the integrated personal OMICS study: proteomics and metabolomics experiments

14 July 2018

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Toward more transparent and reproducible omics studies through a common metadata checklist and data publications

14 July 2018

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Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy

14 July 2018

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Best practices for scientific computing

14 July 2018

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Mobile phone text messages for improving adherence to antiretroviral therapy (ART): an individual patient data meta-analysis of randomised trials

14 July 2018

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The economic value of personalized medicine tests: what we know and what we need to know

14 July 2018

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Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration

14 July 2018

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Bayesian network prior: network analysis of biological data using external knowledge.

14 July 2018

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cudaMap: a GPU accelerated program for gene expression connectivity mapping

14 July 2018

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Integrated analysis of transcriptomic and proteomic data

14 July 2018

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A sea of standards for omics data: sink or swim?

14 July 2018

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A modular framework for gene set analysis integrating multilevel omics data

14 July 2018

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Systems biology and p4 medicine: past, present, and future

14 July 2018

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Biology: The big challenges of big data

14 July 2018

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Exploiting GPUs in virtual machine for BioCloud

14 July 2018

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Computational solutions for omics data

14 July 2018

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Crowd-funded micro-grants for genomics and "big data": an actionable idea connecting small (artisan) science, infrastructure science, and citizen philanthropy

14 July 2018

1 reference

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Computational tools and resources for prediction and analysis of gene regulatory regions in the chick genome

14 July 2018

1 reference

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Challenges in Biomarker Discovery: Combining Expert Insights with Statistical Analysis of Complex Omics Data.

14 July 2018

1 reference

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Bioinformatics clouds for big data manipulation

14 July 2018

1 reference

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The genetics of type 2 diabetes and its clinical relevance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

The expanding scope of DNA sequencing

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

A travel guide to Cytoscape plugins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

This I believe: gaining new insights through integrating "old" data

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

The changing privacy landscape in the era of big data

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Radiomics: the process and the challenges

14 July 2018

1 reference

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A sparse structure learning algorithm for Gaussian Bayesian Network identification from high-dimensional data

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

A population approach to precision medicine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Joint generalized models for multidimensional outcomes: a case study of neuroscience data from multimodalities

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Unsupervised pattern discovery in human chromatin structure through genomic segmentation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Genomic position mapping discrepancies of commercial SNP chips

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Independent Principal Component Analysis for biologically meaningful dimension reduction of large biological data sets

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Comparing statistical methods for constructing large scale gene networks

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

NEW: network-enabled wisdom in biology, medicine, and health care

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Next generation sequencing and bioinformatic bottlenecks: the current state of metagenomic data analysis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Improving validation practices in "omics" research

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Digital image analysis of membrane connectivity is a robust measure of HER2 immunostains

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

GBOOST: a GPU-based tool for detecting gene–gene interactions in genome–wide case control studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Network medicine: a network-based approach to human disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

The $1,000 genome, the $100,000 analysis?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Cloud computing and the DNA data race

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Public financing of health in developing countries: a cross-national systematic analysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

How does multiple testing correction work?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Molecular networks as sensors and drivers of common human diseases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

integrOmics: an R package to unravel relationships between two omics datasets

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

A platform to standardize, store, and visualize proteomics experimental data

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Multiple testing with minimal assumptions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Genome-wide sparse canonical correlation of gene expression with genotypes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

The properties of high-dimensional data spaces: implications for exploring gene and protein expression data.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

High-throughput sequence alignment using Graphics Processing Units

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

A multivariate analysis approach to the integration of proteomic and gene expression data

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

A data integration methodology for systems biology: experimental verification

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Finishing the euchromatic sequence of the human genome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Bioconductor: open software development for computational biology and bioinformatics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

How can we help? From "sociology in" to "sociology of" bioethics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Cross-platform comparison and visualisation of gene expression data using co-inertia analysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Discordant protein and mRNA expression in lung adenocarcinomas

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Using Bayesian networks to analyze expression data

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Correlation between protein and mRNA abundance in yeast

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

The tragedy of the commons. The population problem has no technical solution; it requires a fundamental extension in morality

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Epidemiology faces its limits.

14 July 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

Personalized medicine: the medicine of tomorrow. Foreword

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

The next steps for genomic medicine: challenges and opportunities for the developing world.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

21 January 2018

tragedy of the commons

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

The epiknowledge of socially responsible innovation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

A view of cloud computing

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

Statistics for High-Dimensional Data

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

Genes associated with genotype-specific DNA methylation in squamous cell carcinoma as candidate drug targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

Genome‐wide Correlation between mRNA and Protein in a Single Cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

Lab-on-a-chip-based high-throughput screening of the genotoxicity of engineered nanomaterials.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482045

Computational science: ...Error

25 November 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12920-015-0108-Y

Human genome 10th anniversary. Waiting for the revolution

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26112054

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cloud and heterogeneous computing solutions exist today for the emerging big data problems in biology

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26112054

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12920-015-0108-Y

1 reference

Dimensions Publication ID

29 October 2017

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12920-015-0108-y

1 reference

29 October 2017

PubMed publication ID

26112054

1 reference