DNA-AP sites generation by etoposide in whole blood cells. (Q30886598)

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12 February 2020

title

DNA-AP sites generation by etoposide in whole blood cells (English)

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12 February 2020

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4

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12 February 2020

Emilio Rojas

series ordinal

1

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12 February 2020

author name string

Patricia Mussali

series ordinal

2

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12 February 2020

Efrain Tovar

series ordinal

3

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12 February 2020

language of work or name

English

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publication date

16 November 2009

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12 February 2020

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12 February 2020

volume

9

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12 February 2020

page(s)

398

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Ascorbic acid suppresses drug-induced apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions

12 February 2020

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A two-drug model for etoposide action against human topoisomerase IIalpha

21 June 2018

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Cellular roles of dna topoisomerases: a molecular perspective

21 June 2018

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Positioning the 3'-DNA terminus for topoisomerase II-mediated religation

21 June 2018

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Influence of cell cycle and oncogene activity upon topoisomerase IIalpha expression and drug toxicity

21 June 2018

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Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

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Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice

21 June 2018

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Single cell gel electrophoresis assay: methodology and applications

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21 June 2018

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Etoposide: four decades of development of a topoisomerase II inhibitor

21 January 2018

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Absence of topoisomerase IIbeta in an amsacrine-resistant human leukemia cell line with mutant topoisomerase IIalpha.

21 June 2018

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The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay).

21 June 2018

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21 June 2018

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DNA damage induced by etoposide; a comparison of two different methods for determination of strand breaks in DNA.

21 June 2018

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Differential expression of the topoisomerase II alpha and beta genes in human breast cancers

21 June 2018

1 reference

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Interactions of phenoxyl radical of antitumor drug, etoposide, with reductants in solution and in cell and nuclear homogenates: electron spin resonance and high-performance liquid chromatography

21 June 2018

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Etoposide: twenty years later.

21 June 2018

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Topoisomerase II-mediated DNA breaks and cytotoxicity in relation to cell proliferation and the cell cycle in NIH 3T3 fibroblasts and L1210 leukemia cells

21 June 2018

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Mechanism of action of antitumor drug etoposide: a review

21 June 2018

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Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide.

21 June 2018

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Effects of antineoplastic drugs on the post-strand-passage DNA cleavage/religation equilibrium of topoisomerase II.

21 June 2018

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Mechanisms of action of teniposide (VM-26) and comparison with etoposide (VP-16)

21 June 2018

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Escherichia coli Mutants Thermosensitive for Deoxyribonucleic Acid Gyrase Subunit A: Effects on Deoxyribonucleic Acid Replication, Transcription, and Bacteriophage Growth

21 June 2018

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Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine

21 June 2018

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Human topoisomerase IIalpha possesses an intrinsic nucleic acid specificity for DNA ligation. Use of 5' covalently activated oligonucleotide substrates to study enzyme mechanism

21 January 2018

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Characterization of free radicals produced during oxidation of etoposide (VP-16) and its catechol and quinone derivatives. An ESR Study

21 January 2018

1 reference

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Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems.

21 January 2018

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Cloning of the exonuclease III gene of Escherichia coli

21 January 2018

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Oxidative stress in humans: validation of biomarkers of DNA damage

21 January 2018

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Exposure to low concentrations of etoposide reduces the apoptotic capability of leukaemic cell lines.

21 January 2018

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Investigating the biological functions of DNA topoisomerases in eukaryotic cells

21 January 2018

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Semi-quinone formation from the catechol and ortho-quinone metabolites of the antitumor agent VP-16-213

21 January 2018

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12 December 2020

Monoclonal antibodies to human DNA topoisomerase I and the two isoforms of DNA topoisomerase II: 170- and 180-kDa isozymes

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12 December 2020

Accumulation of DNA damage in the organs of mice deficient in γ-glutamyltranspeptidase

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12 December 2020

Genotoxicity of several clinically used topoisomerase II inhibitors

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12 December 2020

Growth fraction measured using the comet assay

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12 December 2020

Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants

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12 December 2020

Antioxidant paradoxes of phenolic compounds: peroxyl radical scavenger and lipid antioxidant, etoposide (VP-16), inhibits sarcoplasmic reticulum Ca(2+)-ATPase via thiol oxidation by its phenoxyl radical

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12 December 2020

Analysis of DNA alkylation damage and repair in mammalian cells by the comet assay

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12 December 2020

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

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12 December 2020

Catalytic inhibitors of DNA topoisomerase II

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12 December 2020

The response of eukaryotic topoisomerases to DNA damage

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12 December 2020

Induction of apoptosis by deregulated expression of DNA topoisomerase IIalpha

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12 December 2020

The nature and origin of DNA single-strand breaks determined with the comet assay

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12 December 2020

Apoptosis of unstimulated human lymphocytes and DNA strand breaks induced by the topoisomerase II inhibitor etoposide (VP-16)

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12 December 2020

Expression of the 170-kDa and 180-kDa isoforms of DNA topoisomerase II in resting and proliferating human lymphocytes

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12 December 2020

Alkali-labile sites in sperm cells from Sus and Ovis species

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1186/1471-2407-9-398

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19917085%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 February 2020

0 references

1 reference

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12 February 2020

PubMed publication ID

19917085

1 reference