CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium. (Q30665963)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404741%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium (English)

1 reference

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24 February 2020

6

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24 February 2020

Concepción Lillo

9

1 reference

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24 February 2020

Almudena Velasco

7

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24 February 2020

author name string

Antonio E Paniagua

1

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24 February 2020

Saúl Herranz-Martín

2

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24 February 2020

David Jimeno

3

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24 February 2020

Ángela M Jimeno

4

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24 February 2020

Saray López-Benito

5

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24 February 2020

José Aijón

8

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24 February 2020

language of work or name

English

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publication date

25 September 2015

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24 February 2020

1 reference

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24 February 2020

volume

5

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24 February 2020

page(s)

14504

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Creative Commons Attribution 4.0 International

24 February 2020

copyright license

start time

25 September 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4585915/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.

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Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background

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Evolution and cell physiology. 4. Why invent yet another protein complex to build junctions in epithelial cells?

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Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene

14 July 2018

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Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis.

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PALS1 is essential for retinal pigment epithelium structure and neural retina stratification.

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Deficiency in crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice

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Integration of tight junctions and claudins with the barrier functions of the retinal pigment epithelium

14 July 2018

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The apical complex couples cell fate and cell survival to cerebral cortical development

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Human CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complex

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Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm

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Crumbs proteins in epithelial morphogenesis

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Intact retinal pigment epithelium maintained by Nok is essential for retinal epithelial polarity and cellular patterning in zebrafish

14 July 2018

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Composition and function of the Crumbs protein complex in the mammalian retina

14 July 2018

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The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes

14 July 2018

1 reference

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Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells

14 July 2018

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FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex

14 July 2018

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14 July 2018

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A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin beta interactions

14 July 2018

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MPP1 links the Usher protein network and the Crumbs protein complex in the retina

14 July 2018

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14 July 2018

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14 July 2018

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Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells

14 July 2018

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14 July 2018

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Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells

14 July 2018

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14 July 2018

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Characterization of the Crumbs homolog 2 (CRB2) gene and analysis of its role in retinitis pigmentosa and Leber congenital amaurosis.

14 July 2018

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CRB1 mutation spectrum in inherited retinal dystrophies

14 July 2018

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Polarity proteins control ciliogenesis via kinesin motor interactions

14 July 2018

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Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure

14 July 2018

1 reference

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DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

14 July 2018

1 reference

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CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells

14 July 2018

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Loss of PALS1 expression leads to tight junction and polarity defects.

14 July 2018

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14 July 2018

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The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

Adaptation of core mechanisms to generate cell polarity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

The polarity of the retinal pigment epithelium

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

CRB1 has a cytoplasmic domain that is functionally conserved between human and Drosophila

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

Leber congenital amaurosis and retinitis pigmentosa with Coats-like exudative vasculopathy are associated with mutations in the crumbs homologue 1 (CRB1) gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585915

A conserved motif in Crumbs is required for E-cadherin localisation and zonula adherens formation in Drosophila

14 July 2018

1 reference

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.

21 January 2018

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Crumbs and stardust act in a genetic pathway that controls the organization of epithelia in Drosophila melanogaster

21 January 2018

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The apical polarity determinant Crumbs 2 is a novel regulator of ESC-derived neural progenitors.

21 January 2018

1 reference

CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice

21 January 2018

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Retromer Controls Epithelial Cell Polarity by Trafficking the Apical Determinant Crumbs

21 January 2018

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Cell Survival through Trk Neurotrophin Receptors Is Differentially Regulated by Ubiquitination

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26404741

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP14504

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404741%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404741%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

26404741

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26404741%20AND%20SRC:MED&resulttype=core&format=json