Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration (Q30660919)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26268945%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migration (English)

1 reference

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22 February 2020

1 reference

1 reference

1 reference

8

1 reference

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22 February 2020

author name string

Kingsley O Osuala

1

1 reference

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22 February 2020

Mansoureh Sameni

2

1 reference

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22 February 2020

Seema Shah

3

1 reference

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22 February 2020

Neha Aggarwal

4

1 reference

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22 February 2020

Michelle L Simonait

5

1 reference

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22 February 2020

Omar E Franco

6

1 reference

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22 February 2020

Yan Hong

7

1 reference

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22 February 2020

Fariba Behbod

9

1 reference

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22 February 2020

Raymond R Mattingly

10

1 reference

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22 February 2020

Bonnie F Sloane

11

1 reference

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22 February 2020

language of work or name

English

0 references

publication date

13 August 2015

1 reference

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22 February 2020

1 reference

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22 February 2020

volume

15

1 reference

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22 February 2020

page(s)

584

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Evaluation of chemotherapeutics in a three-dimensional breast cancer model

22 February 2020

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Cancer-associated fibroblasts as another polarized cell type of the tumor microenvironment

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Syndecan-1 (CD138) modulates triple-negative breast cancer stem cell properties via regulation of LRP-6 and IL-6-mediated STAT3 signaling

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Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling

20 June 2018

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Prognostic role of interleukin-6, interleukin-8, and leptin levels according to breast cancer subtype

20 June 2018

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Understanding the impact of 2D and 3D fibroblast cultures on in vitro breast cancer models

20 June 2018

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Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression

20 June 2018

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'Cancer associated fibroblasts'--more than meets the eye.

20 June 2018

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Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins

20 June 2018

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Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8.

20 June 2018

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Up-regulated cten by FGF2 contributes to FGF2-mediated cell migration

20 June 2018

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Oxymatrine prevents NF-κB nuclear translocation and ameliorates acute intestinal inflammation.

20 June 2018

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The role of intratumoral and systemic IL-6 in breast cancer

20 June 2018

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The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

20 June 2018

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Interleukin-6 signaling pathway in targeted therapy for cancer

20 June 2018

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20 June 2018

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Cancer invasion and the microenvironment: plasticity and reciprocity

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20 June 2018

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Down-regulation of expression of interleukin-6 and its receptor results in growth inhibition of MCF-7 breast cancer cells

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Innate immune cells in breast cancer--from villains to heroes?

20 June 2018

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20 June 2018

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20 June 2018

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Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma

20 June 2018

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Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects

20 June 2018

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Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation

20 June 2018

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A phase I/II study of siltuximab (CNTO 328), an anti-interleukin-6 monoclonal antibody, in metastatic renal cell cancer

20 June 2018

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Clinical and correlative results of SWOG S0354: a phase II trial of CNTO328 (siltuximab), a monoclonal antibody against interleukin-6, in chemotherapy-pretreated patients with castration-resistant prostate cancer

20 June 2018

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20 June 2018

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Interleukin-6 increases expression and secretion of cathepsin B by breast tumor-associated monocytes

20 June 2018

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Ductal carcinoma in situ of the breast: a systematic review of incidence, treatment, and outcomes

20 June 2018

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Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ

20 June 2018

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20 June 2018

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Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

20 June 2018

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Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation

20 June 2018

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20 June 2018

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20 June 2018

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Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer

20 June 2018

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Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression

20 June 2018

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20 June 2018

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Stromal fibroblasts in cancer: a novel tumor-promoting cell type

20 June 2018

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Distinct epigenetic changes in the stromal cells of breast cancers

20 June 2018

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

20 June 2018

1 reference

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Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling.

20 June 2018

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Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients

20 June 2018

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The organizing principle: microenvironmental influences in the normal and malignant breast

20 June 2018

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Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues

20 June 2018

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Diversity, topographic differentiation, and positional memory in human fibroblasts

20 June 2018

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A two-way interaction between hepatocyte growth factor and interleukin-6 in tissue invasion of lung cancer cell line

20 June 2018

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New functions for the matrix metalloproteinases in cancer progression

20 June 2018

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Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue

20 June 2018

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Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

20 June 2018

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Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass

20 June 2018

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MCF10AT: a model for the evolution of cancer from proliferative breast disease

20 June 2018

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Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene.

20 June 2018

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20 June 2018

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Soluble receptors for cytokines and growth factors: generation and biological function

20 June 2018

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Expression and function of interleukin-6 in epithelial cells

20 June 2018

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Decreased adherence of interleukin 6-treated breast carcinoma cells can lead to separation from neighbors after mitosis

20 June 2018

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Role of PRL-3, Snail, Cytokeratin and Vimentin expression in epithelial mesenchymal transition in breast carcinoma.

20 June 2018

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Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium.

21 January 2018

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A phase 2 multicentre study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with relapsed or refractory multiple myeloma

21 January 2018

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Clonal Mutations in the Cancer-Associated Fibroblasts: The Case against Genetic Coevolution

21 January 2018

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The natural history of low-grade ductal carcinoma in situ of the breast in women treated by biopsy only revealed over 30 years of long-term follow-up

21 January 2018

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12 December 2020

Interleukin-6 and soluble interleukin-6 receptor: direct stimulation of gp130 and hematopoiesis

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12 December 2020

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12 December 2020

Continued local recurrence of carcinoma 15-25 years after a diagnosis of low grade ductal carcinoma in situ of the breast treated only by biopsy

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12 December 2020

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12 December 2020

Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas

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Circulating interleukin-6 predicts survival in patients with metastatic breast cancer

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12 December 2020

Serum interleukin-6 level reflects the tumor proliferative activity in patients with colorectal carcinoma

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12 December 2020

10.1186/S12885-015-1576-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26268945%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 February 2020

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12885-015-1576-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26268945%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

26268945

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26268945%20AND%20SRC:MED&resulttype=core&format=json