Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease (Q30453755)

17 August 2017

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease (English)

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17 August 2017

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Abraham Acevedo-Arozena

object named as

Abraham Acevedo-Arozena

6

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author name string

Hilda Tateossian

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17 August 2017

Susan Morse

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17 August 2017

Andrew Parker

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17 August 2017

Philomena Mburu

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17 August 2017

Nick Warr

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17 August 2017

Michael Cheeseman

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17 August 2017

Sara Wells

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17 August 2017

Steve D M Brown

9

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17 August 2017

3 March 2013

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17 August 2017

Human Molecular Genetics

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17 August 2017

22

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17 August 2017

13

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17 August 2017

2553-2565

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3674796/fullTextXML

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inferred from PubMed Central ID database lookup

cites work

Genome-wide association study to identify the genetic determinants of otitis media susceptibility in childhood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.

20 June 2018

1 reference

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Unraveling the genetics of otitis media: from mouse to human and back again

20 June 2018

1 reference

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Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia

20 June 2018

1 reference

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Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

PCTA: a new player in TGF-beta signaling

20 June 2018

1 reference

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Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signalling

20 June 2018

1 reference

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Maternal Tgif is required for vascularization of the embryonic placenta

20 June 2018

1 reference

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20 June 2018

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Activities of matrix metalloproteinases and tissue inhibitor of metalloproteinase-2 in idiopathic hemotympanum and otitis media with effusion

20 June 2018

1 reference

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A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media

20 June 2018

1 reference

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Nuclear retention of the tumor suppressor cPML by the homeodomain protein TGIF restricts TGF-beta signaling

20 June 2018

1 reference

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Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: the Minnesota COME/ROM Family Study

20 June 2018

1 reference

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TGIF inhibits retinoid signaling

20 June 2018

1 reference

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Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Chronic and recurrent otitis media: a genome scan for susceptibility loci

20 June 2018

1 reference

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The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Cytoplasmic PML function in TGF-beta signalling

20 June 2018

1 reference

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The deaf mouse mutant Jeff (Jf) is a single gene model of otitis media

20 June 2018

1 reference

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

20 June 2018

1 reference

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Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

20 June 2018

1 reference

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TGIF2 interacts with histone deacetylase 1 and represses transcription

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Amplification and overexpression of TGIF2, a novel homeobox gene of the TALE superclass, in ovarian cancer cell lines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

20 June 2018

1 reference

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Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Controlling TGF-beta signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

A Smad transcriptional corepressor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Human CPR (Cell Cycle Progression Restoration) Genes Impart a Far– Phenotype on Yeast Cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Regulation of vascular endothelial growth factor by hypoxia and its modulation by the von Hippel-Lindau tumor suppressor gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

A novel homeobox protein which recognizes a TGT core and functionally interferes with a retinoid-responsive motif

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Physical mapping of the holoprosencephaly critical region in 18p11.3

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

FBXO11, a regulator of the TGFβ pathway, is associated with severe otitis media in Western Australian children.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Mechanisms underlying TGF-beta1-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

The genetic component of middle ear disease in the first 5 years of life

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3674796

Multiple modes of repression by the Smad transcriptional corepressor TGIF

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23459932

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDT103

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23459932

1 reference