The timing of TCR alpha expression critically influences T cell development and selection (Q30443379)

14 August 2017

The timing of TCR alpha expression critically influences T cell development and selection (English)

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14 August 2017

Stephen C Jameson

3

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Kristin A. Hogquist

object named as

Kristin A Hogquist

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4

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author name string

Troy A Baldwin

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1

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14 August 2017

Michelle M Sandau

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2

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14 August 2017

language of work or name

English

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publication date

1 July 2005

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Journal of Experimental Medicine

14 August 2017

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14 August 2017

202

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14 August 2017

1

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14 August 2017

111-121

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The fourth way? Harnessing aggressive tendencies in the thymus

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Starting at the beginning: new perspectives on the biology of mucosal T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Calcineurin B1 is essential for positive but not negative selection during thymocyte development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Pre-TCRalpha and TCRalpha are not interchangeable partners of TCRbeta during T lymphocyte development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Negative selection--clearing out the bad apples from the T-cell repertoire

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Positive and negative selection of T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Regulation of thymocyte differentiation: pre-TCR signals and beta-selection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Maintaining the norm: T-cell homeostasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

A nonredundant role for the adapter protein Shc in thymic T cell development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Interactions between double positive thymocytes and high affinity ligands presented by cortical epithelial cells generate double negative thymocytes with T cell regulatory activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Cutting edge: positive selection induced by a self-peptide with TCR antagonist activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Biological insights into TCRgammadelta+ and TCRalphabeta+ intraepithelial lymphocytes provided by serial analysis of gene expression (SAGE).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

MHC class I allele dosage alters CD8 expression by intestinal intraepithelial lymphocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Requirement for a complex array of costimulators in the negative selection of autoreactive thymocytes in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Premature expression of T cell receptor (TCR)alphabeta suppresses TCRgammadelta gene rearrangement but permits development of gammadelta lineage T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Several different cell surface molecules control negative selection of medullary thymocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

An opposite pattern of selection of a single T cell antigen receptor in the thymus and among intraepithelial lymphocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

An essential role for gp39, the ligand for CD40, in thymic selection.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Peripheral selection of the T cell repertoire

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Selection of intraepithelial lymphocytes with CD8 alpha/alpha co-receptors by self-antigen in the murine gut

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

In vivo and in vitro clonal deletion of double-positive thymocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development

20 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

A role for TCR affinity in regulating naive T cell homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

TCR/self-antigen interactions drive double-negative T cell peripheral expansion and differentiation into suppressor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

T cell tolerance by clonal elimination in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

A role for the B7-1/B7-2:CD28/CTLA-4 pathway during negative selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

Negative selection by endogenous antigen and superantigen occurs at multiple thymic sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

T-cell development in the absence of the pre-T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

TNF receptor-deficient mice reveal striking differences between several models of thymocyte negative selection.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212895

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

26 November 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

T-cell apoptosis detected in situ during positive and negative selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20050359

Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides

21 January 2018

1 reference

12 December 2020

Origin of regulatory T cells with known specificity for antigen

1 reference

12 December 2020

1 reference

12 December 2020

Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages

1 reference

12 December 2020

A TCR alpha chain transgene induces maturation of CD4- CD8- alpha beta+ T cells from gamma delta T cell precursors

1 reference

12 December 2020

Competitive displacement of pT alpha by TCR-alpha during TCR assembly prevents surface coexpression of pre-TCR and alpha beta TCR

1 reference

12 December 2020

Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

1 reference

12 December 2020

Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development

1 reference

12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20050359

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

15998791

1 reference