Intrinsic fibrillation of fast-acting insulin analogs (Q30416114)

18 October 2017

Intrinsic fibrillation of fast-acting insulin analogs (English)

1 reference

18 October 2017

1 reference

1 reference

R Jeremy Woods

1

1 reference

18 October 2017

Javier Alarcón

series ordinal

2

1 reference

18 October 2017

Elaine McVey

series ordinal

3

1 reference

18 October 2017

Ronald J Pettis

series ordinal

4

1 reference

18 October 2017

1 March 2012

1 reference

Journal of Diabetes Science and Technology

18 October 2017

1 reference

18 October 2017

6

1 reference

18 October 2017

2

1 reference

18 October 2017

265-276

1 reference

Macrocyclic β-sheet peptides that inhibit the aggregation of a tau-protein-derived hexapeptide

18 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Strategies to increase the reproducibility of protein fibrillization in plate reader assays

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Stability of protein pharmaceuticals: an update

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Molecular basis for insulin fibril assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Formation mechanism of insulin fibrils and structural aspects of the insulin fibrillation process.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Protein aggregation: pathways, induction factors and analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Principles, approaches, and challenges for predicting protein aggregation rates and shelf life

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Insulin glulisine complementing basal insulins: a review of structure and activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Polymorphism in the intermediates and products of amyloid assembly

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Effects of protein aggregates: an immunologic perspective

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Kinetics of insulin aggregation: disentanglement of amyloid fibrillation from large-size cluster formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Structure of the cross-beta spine of amyloid-like fibrils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

The aggregation kinetics of Alzheimer's beta-amyloid peptide is controlled by stochastic nucleation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Protein aggregation and its inhibition in biopharmaceutics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Protein aggregation and neurodegenerative disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Progress towards a molecular-level structural understanding of amyloid fibrils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Sequence determinants of amyloid fibril formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Rationalization of the effects of mutations on peptide and protein aggregation rates.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

The protofilament structure of insulin amyloid fibrils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Toxic proteins in neurodegenerative disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Formation of insulin amyloid fibrils followed by FTIR simultaneously with CD and electron microscopy.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Insulin analogs with improved pharmacokinetic profiles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Amyloid fibrillogenesis: themes and variations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Designing conditions for in vitro formation of amyloid protofilaments and fibrils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Temperature dependence of amyloid beta-protein fibrillization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

The new era of biotech insulin analogues

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Mechanisms of stabilization of the insulin hexamer through allosteric ligand interactions.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Toward understanding insulin fibrillation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Physicochemical basis for the rapid time-action of LysB28ProB29-insulin: dissociation of a protein-ligand complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric LysB28ProB29-human insulin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

The accurate measurement of insulin molarity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Kinetics of insulin aggregation in aqueous solutions upon agitation in the presence of hydrophobic surfaces

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3380767

Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism

20 June 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Mechanism of insulin aggregation and stabilization in agitated aqueous solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Partially folded intermediates in insulin fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Early events in the fibrillation of monomeric insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Technical risks with subcutaneous insulin infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

The changing face of glucagon fibrillation: structural polymorphism and conformational imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Evidence for a partially folded intermediate in alpha-synuclein fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Glucagon amyloid-like fibril morphology is selected via morphology-dependent growth inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein. Insights into transition states from pressure, temperature, and co-solute studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Absolute correlation between lag time and growth rate in the spontaneous formation of several amyloid-like aggregates and fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

A Role for Protein Misfolding in Immunogenicity of Biopharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Kinetics of Different Processes in Human Insulin Amyloid Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F193229681200600209

Quaternary conformational stability: the effect of reversible self-association on the fibrillation of two insulin analogs

21 January 2018

1 reference

12 December 2020

1 reference

12 December 2020

Diabetic ketoacidosis caused by exposure of insulin pump to heat and sunlight

1 reference

12 December 2020

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

1 reference

12 December 2020

Use of insulin aspart, a fast-acting insulin analog, as the mealtime insulin in the management of patients with type 1 diabetes

1 reference

12 December 2020

Binding mode of Thioflavin T in insulin amyloid fibrils

1 reference

12 December 2020

Cooperativity and intermediate states in the T----R-structural transformation of insulin

1 reference

12 December 2020

A false paradise - mixed blessings in the protein universe: the amyloid as a new challenge in drug development

1 reference

12 December 2020

Self-association properties of monomeric insulin analogs under formulation conditions

1 reference

12 December 2020

10.1177/193229681200600209

Identifiers

DOI

1 reference

18 October 2017

1 reference

18 October 2017

PubMed publication ID

22538135

1 reference