Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins. (Q30388525)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226597%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins (English)

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2 April 2020

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Philipp Knyphausen

1

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2 April 2020

Susanne de Boor

2

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2 April 2020

Nora Kuhlmann

3

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2 April 2020

Lukas Scislowski

4

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2 April 2020

Antje Extra

5

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2 April 2020

Linda Baldus

6

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2 April 2020

Ulrich Baumann

8

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2 April 2020

Michael Lammers

10

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2 April 2020

language of work or name

English

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publication date

18 May 2016

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Journal of Biological Chemistry

2 April 2020

published in

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volume

291

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2 April 2020

issue

28

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2 April 2020

page(s)

14677-14694

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describes a project that uses

2 April 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4938187/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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The aurora kinases in cell cycle and leukemia

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How good are my data and what is the resolution?

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Sirtuins in cognitive ageing and Alzheimer's disease

20 June 2018

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The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells

20 June 2018

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Proteome-Wide Mapping of the Drosophila Acetylome Demonstrates a High Degree of Conservation of Lysine Acetylation

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Catalysis and Mechanistic Insights into Sirtuin Activation

20 June 2018

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Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

20 June 2018

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Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

20 June 2018

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20 June 2018

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SIRT3 substrate specificity determined by peptide arrays and machine learning

20 June 2018

1 reference

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Peptide arrays identify isoform-selective substrates for profiling endogenous lysine deacetylase activity

20 June 2018

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Sirtuin mechanism and inhibition: explored with Nε-acetyl-lysine analogs

20 June 2018

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Dietary restriction: standing up for sirtuins

20 June 2018

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20 June 2018

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20 June 2018

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A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis

20 June 2018

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Mammalian sirtuins: biological insights and disease relevance

20 June 2018

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20 June 2018

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20 June 2018

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

20 June 2018

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The many roles of histone deacetylases in development and physiology: implications for disease and therapy

20 June 2018

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20 June 2018

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Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau

20 June 2018

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20 June 2018

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Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli

20 June 2018

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Acetylation is indispensable for p53 activation

20 June 2018

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The Sirtuin family: therapeutic targets to treat diseases of aging

20 June 2018

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SIRT1 transgenic mice show phenotypes resembling calorie restriction

20 June 2018

1 reference

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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

20 June 2018

1 reference

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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

20 June 2018

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Protein tyrosine phosphatases: from genes, to function, to disease

20 June 2018

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Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

20 June 2018

1 reference

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Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.

20 June 2018

1 reference

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Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme

20 June 2018

1 reference

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WebLogo: A Sequence Logo Generator

20 June 2018

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Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2′-O-Acetyl ADP Ribose and Histone Peptide

20 June 2018

1 reference

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ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Structure of a Sir2 enzyme bound to an acetylated p53 peptide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Histone acetyltransferases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Improved R-factors for diffraction data analysis in macromolecular crystallography

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

A direct link between core histone acetylation and transcriptionally active chromatin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Cloning and characterization of four SIR genes of Saccharomyces cerevisiae

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

SnapShot: sirtuins, NAD, and aging.

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.726307

Identification of a cell-active non-peptide sirtuin inhibitor containing N-thioacetyl lysine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.726307

Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.726307

Unstructured conformations are a substrate requirement for the Sir2 family of NAD-dependent protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.726307

Kinetic characterization of recombinant human cytosolic phosphoenolpyruvate carboxykinase with and without a His10-tag.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.726307

Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.726307

Temperature dependence of backbone dynamics in loops of human mitochondrial heat shock protein 10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.726307

Free R value: cross-validation in crystallography

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4938187

Sirtuins Caught in the Act

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27226597

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sirtuins and calorie restriction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27226597

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M116.726307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226597%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27226597%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

PubMed publication ID

27226597

1 reference