Aurora A Dmel_CG3068 (Q29814459)

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Protein found in Drosophila melanogaster

aurA
aurora kinase
early-A
CG3068 gene product from transcript CG3068-RA
CG3068-PA
aurora-A
aurA-PA
fruhe2
A-type aurora kinase
Aurora-A kinase
aurora A
AuroraA
aurora A kinase
aurora

Language	Label	Description	Also known as
English	Aurora A Dmel_CG3068	Protein found in Drosophila melanogaster	aurA aurora kinase early-A CG3068 gene product from transcript CG3068-RA CG3068-PA aurora-A aurA-PA fruhe2 A-type aurora kinase Aurora-A kinase aurora A AuroraA aurora A kinase aurora

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VGF9

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VGF9

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

protein kinase activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

protein binding

determination method or standard

1 reference

8 April 2019

Mitotic activation of the kinase Aurora-A requires its binding partner Bora

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

transferase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

histone serine kinase activity

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

determination method or standard

1 reference

8 April 2019

Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

spindle microtubule

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

spindle pole centrosome

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

chromosome passenger complex

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

spindle midzone

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

biological process

protein phosphorylation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

determination method or standard

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VGF9&geneProductId=UniProtKB:Q9VGF9

determination method or standard

mitotic spindle organization

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

centrosome cycle

determination method or standard

1 reference

8 April 2019

Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

mitotic centrosome separation

determination method or standard

1 reference

8 April 2019

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

pole cell formation

determination method or standard

1 reference

8 April 2019

Transport of Germ Plasm on Astral Microtubules Directs Germ Cell Development in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

peptidyl-serine phosphorylation

determination method or standard

1 reference

8 April 2019

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

regulation of cytokinesis

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

asymmetric protein localization involved in cell fate determination

determination method or standard

3 references

8 April 2019

Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

8 April 2019

Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

8 April 2019

Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

centrosome separation

determination method or standard

1 reference

8 April 2019

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

symmetric cell division

determination method or standard

1 reference

8 April 2019

Aurora A triggers Lgl cortical release during symmetric division to control planar spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

regulation of protein localization to cell cortex

determination method or standard

1 reference

8 April 2019

Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VGF9

determination method or standard

serine/threonine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VGF9

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VGF9

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VGF9

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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