Loss of the Birt–Hogg–Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription (Q28595056)

1 February 2017

title

Loss of the Birt-Hogg-Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription (English)

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.628

1 February 2017

Loss of the Birt–Hogg–Dubé tumor suppressor results in apoptotic resistance due to aberrant TGFβ-mediated transcription (English)

1 reference

22 November 2024

0 references

1 reference

GOA release 2020-03-11

author name string

T. P. Cash

1

1 reference

1 February 2017

J. J. Gruber

2

1 reference

1 February 2017

T. R. Hartman

3

1 reference

1 February 2017

E. P. Henske

4

1 reference

1 February 2017

M. C. Simon

5

1 reference

1 February 2017

language of work or name

English

0 references

publication date

2 June 2011

1 reference

1 February 2017

24 January 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21258407

full work available at URL

22 November 2024

https://www.nature.com/articles/onc2010628.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21258407

https://europepmc.org/articles/PMC3109270

22 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21258407

https://europepmc.org/articles/PMC3109270?pdf=render

22 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21258407

http://www.nature.com/articles/onc2010628.pdf

22 November 2024

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.628

http://www.nature.com/articles/onc2010628

22 November 2024

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.628

22 November 2024

1 reference

1 February 2017

volume

30

1 reference

1 February 2017

issue

22

1 reference

1 February 2017

page(s)

2534–2546

1 reference

Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling

1 February 2017

cites work

1 reference

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Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2

17 March 2017

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Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin

17 March 2017

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Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation

17 March 2017

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The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis

17 March 2017

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betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis

17 March 2017

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17 March 2017

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BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reports

17 March 2017

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Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys

17 March 2017

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Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

17 March 2017

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Growth factor regulation of autophagy and cell survival in the absence of apoptosis

17 March 2017

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Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome

17 March 2017

1 reference

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Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

17 March 2017

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

17 March 2017

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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

17 March 2017

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Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

17 March 2017

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The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

17 March 2017

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ER stress triggers apoptosis by activating BH3-only protein Bim

7 April 2017

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Transforming growth factor-beta1 (TGF-beta1) induces human osteoclast apoptosis by up-regulating Bim.

7 April 2017

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CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma.

29 September 2017

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The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL).

29 September 2017

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Essential and overlapping functions for mammalian Argonautes in microRNA silencing

29 September 2017

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TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2

29 September 2017

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Identification of the gene transcription and apoptosis mediated by TGF-beta-Smad2/3-Smad4 signaling

29 September 2017

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Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.

29 September 2017

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Analysis of apoptosis by propidium iodide staining and flow cytometry

29 September 2017

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Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription

29 September 2017

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Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis

29 September 2017

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Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence

29 September 2017

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HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

29 September 2017

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Alterations in components of the TGF-beta superfamily signaling pathways in human cancer

29 September 2017

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Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109270

A germ-line insertion in the Birt-Hogg-Dubé (BHD) gene gives rise to the Nihon rat model of inherited renal cancer

29 September 2017

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Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a).

29 September 2017

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Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes

29 September 2017

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Multilineage embryonic hematopoiesis requires hypoxic ARNT activity

29 September 2017

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TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

29 September 2017

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The Effect of Erythropoietin on Colonial Growth of Erythroid Precursor Cells In Vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109270

The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109270

Mutations of the Birt Hogg Dube gene in patients with multiple lung cysts and recurrent pneumothorax

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109270

The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109270

High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109270

Inactivation of BHD in sporadic renal tumors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109270

Transforming growth factor-beta signalling in extraembryonic mesoderm is required for yolk sac vasculogenesis in mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109270

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

27 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2010.628

Familial non-VHL clear cell (conventional) renal cell carcinoma: clinical features, segregation analysis, and mutation analysis of FLCN

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2010.628

Regulation of programmed cell death by plasminogen activator inhibitor type 1 (PAI-1)

31 March 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/21258407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21258407

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2010.628

1 reference

Dimensions Publication ID

1005269709

0 references

Fatcat ID

release_jt5wmko4nbcwbiytgbk2dmztjq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jt5wmko4nbcwbiytgbk2dmztjq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

1 reference

1 reference