Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node (Q28594387)

31 January 2017

title

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node (English)

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Smoothened, frizzled class receptor

31 January 2017

main subject

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Indian hedgehog

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Patched 1

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Sonic hedgehog

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author name string

X. M. Zhang

series ordinal

1

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31 January 2017

M. Ramalho-Santos

series ordinal

2

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31 January 2017

A. P. McMahon

series ordinal

3

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31 January 2017

language of work or name

English

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publication date

27 July 2001

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31 January 2017

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31 January 2017

volume

106

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31 January 2017

issue

2

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31 January 2017

page(s)

781–792

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Cloning of a mouse smoothened cDNA and expression patterns of hedgehog signalling molecules during chondrogenesis and cartilage differentiation in clonal mouse EC cells, ATDC5.

31 January 2017

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7 January 2021

Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system

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7 January 2021

Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

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7 January 2021

HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

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7 January 2021

Sertoli cell signaling by Desert hedgehog regulates the male germline

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7 January 2021

Multiple tissue interactions and signal transduction pathways control somite myogenesis.

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7 January 2021

Mechanisms of left-right determination in vertebrates

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7 January 2021

Characterization of two patched receptors for the vertebrate hedgehog protein family

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7 January 2021

Dual roles for patched in sequestering and transducing Hedgehog

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7 January 2021

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

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7 January 2021

Essential role for Sonic hedgehog during hair follicle morphogenesis

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7 January 2021

Relationship between asymmetric nodal expression and the direction of embryonic turning

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7 January 2021

Wnt signaling and the activation of myogenesis in mammals.

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7 January 2021

Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth

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7 January 2021

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

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7 January 2021

Sclerotome induction and differentiation.

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7 January 2021

Sonic hedgehog promotes neuronal differentiation of murine spinal cord precursors and collaborates with neurotrophin 3 to induce Islet-1

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7 January 2021

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

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7 January 2021

Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog

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7 January 2021

Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway

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7 January 2021

A role of the cryptic gene in the correct establishment of the left-right axis.

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7 January 2021

Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants

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7 January 2021

The world according to hedgehog

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7 January 2021

The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types

1 reference

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7 January 2021

Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein.

1 reference

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7 January 2021

Mediolateral patterning of somites: multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression.

1 reference

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7 January 2021

The role of positive and negative signals in somite patterning

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7 January 2021

A molecular pathway determining left-right asymmetry in chick embryogenesis

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7 January 2021

Sonic hedgehog is essential to foregut development

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7 January 2021

Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells

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7 January 2021

Vertebrate heart development

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7 January 2021

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5

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7 January 2021

In vivo regulation of somite differentiation and proliferation by Sonic Hedgehog

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7 January 2021

Biochemical evidence that patched is the Hedgehog receptor

1 reference

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7 January 2021

A duplicated zone of polarizing activity in polydactylous mouse mutants

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Positional specification of ventricular myosin light chain 2 expression in the primitive murine heart tube

1 reference

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7 January 2021

Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths

1 reference

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7 January 2021

Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Sonic hedgehog regulates branching morphogenesis in the mammalian lung

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Pitx2 participates in the late phase of the pathway controlling left-right asymmetry

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Regulation of left-right patterning in mice by growth/differentiation factor-1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Pitx2 determines left-right asymmetry of internal organs in vertebrates.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

The EGF-CFC gene family in vertebrate development.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Sonic hedgehog signaling is essential for hair development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Activating Smoothened mutations in sporadic basal-cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3

7 January 2021

10.1016/S0092-8674(01)00385-3

Identifiers

DOI

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11440720

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