Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex (Q28592522)

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English	Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex	scientific journal article

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scholarly article

1 reference

PubMed publication ID

31 January 2017

Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex (English)

1 reference

PubMed publication ID

31 January 2017

Cnksr family member 3

1 reference

GOA release 2020-03-11

author name string

Rama Soundararajan

1

1 reference

PubMed publication ID

31 January 2017

Tim Ziera

2

1 reference

PubMed publication ID

31 January 2017

Eric Koo

3

1 reference

PubMed publication ID

31 January 2017

Karen Ling

4

1 reference

PubMed publication ID

31 January 2017

Jian Wang

5

1 reference

PubMed publication ID

31 January 2017

Steffen A. Borden

6

1 reference

PubMed publication ID

31 January 2017

David Pearce

7

1 reference

PubMed publication ID

31 January 2017

language of work or name

0 references

publication date

21 September 2012

1 reference

PubMed publication ID

31 January 2017

Journal of Biological Chemistry

1 reference

PubMed publication ID

31 January 2017

287

1 reference

PubMed publication ID

31 January 2017

39

1 reference

PubMed publication ID

31 January 2017

33014–33025

1 reference

PubMed publication ID

31 January 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3463358/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Analysis of different complexes of type IIa sodium-dependent phosphate transporter in rat renal cortex using blue-native polyacrylamide gel electrophoresis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Sgk kinases and their role in epithelial transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

17 March 2017

Exploring the intricate regulatory network controlling the thiazide-sensitive NaCl cotransporter (NCC)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Dynamic Na+-H+ exchanger regulatory factor-1 association and dissociation regulate parathyroid hormone receptor trafficking at membrane microdomains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Epithelial sodium channel regulation by cell surface-associated serum- and glucocorticoid-regulated kinase 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Cortical actin binding protein cortactin mediates ENaC activityviaArp2/3 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Sodium and potassium balance depends on αENaC expression in connecting tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Glucocorticoid-induced Leucine Zipper 1 Stimulates the Epithelial Sodium Channel by Regulating Serum- and Glucocorticoid-induced Kinase 1 Stability and Subcellular Localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Role of NHERF and scaffolding proteins in proximal tubule transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Role of epithelial sodium channels and their regulators in hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Regulation of the epithelial sodium channel (ENaC) by membrane trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

The physiological impact of the serum and glucocorticoid-inducible kinase SGK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

NHE3 regulatory complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Epithelial sodium channel regulated by differential composition of a signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Scaffold proteins and immune-cell signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Mechanisms of ENaC regulation and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Renal Na+-K+-Cl- cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Solubilization of membrane protein complexes for blue native PAGE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Regulation of epithelial Na+ channels by aldosterone: role of Sgk1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Differential activities of glucocorticoid-induced leucine zipper protein isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

(Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

The scaffold protein CNK1 interacts with the angiotensin II type 2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Minireview: regulation of epithelial Na+ channel trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Serum- and glucocorticoid-regulated kinase 1 regulates ubiquitin ligase neural precursor cell-expressed, developmentally down-regulated protein 4-2 by inducing interaction with 14-3-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

NaPi-IIa and interacting partners.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Nedd4-2 isoforms differentially associate with ENaC and regulate its activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

PDZ interactions and proximal tubular phosphate reabsorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Novel aspects in regulated expression of the renal type IIa Na/Pi-cotransporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

PDZ proteins and proximal ion transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Regulation of epithelial ion transport by aldosterone through changes in gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

SGK1 regulation of epithelial sodium transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Targeted degradation of ENaC in response to PKC activation of the ERK1/2 cascade

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Impaired renal Na(+) retention in the sgk1-knockout mouse

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

A novel anterograde trafficking signal present in the N-terminal extracellular domain of ionotropic glutamate receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

PDZ proteins and polarity: functions from the fly.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Transcriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Regulation of Na(+) reabsorption by the aldosterone-induced small G protein K-Ras2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Association of the epithelial sodium channel with Apx and alpha-spectrin in A6 renal epithelial cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Corticosteroid-dependent sodium transport in a novel immortalized mouse collecting duct principal cell line.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Epithelial sodium channel regulated by aldosterone-induced protein sgk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Characterization of early aldosterone-induced RNAs identified in A6 kidney epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Binding of the proline-rich region of the epithelial Na+ channel to SH3 domains and its association with specific cellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Purification and characterization of the amiloride-sensitive sodium channel from A6 cultured cells and bovine renal papilla

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

29 September 2017

Blue native polyacrylamide gel electrophoresis (BN-PAGE) for analysis of multiprotein complexes from cellular lysates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

3 June 2018

Cell surface expression and biosynthesis of epithelial Na+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

3 June 2018

Purified epithelial Na+ channel complex contains the pertussis toxin-sensitive G alpha i-3 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463358

3 June 2018

ANG II provokes acute trafficking of distal tubule Na+-Cl(-) cotransporter to apical membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389148

21 January 2018

Fluorescence resonance energy transfer analysis of subunit stoichiometry of the epithelial Na+ channel

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https://api.crossref.org/works/10.1074%2FJBC.M112.389148

21 January 2018

Carbachol regulation of rabbit ileal brush border Na+-H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389148

21 January 2018

Two-dimensional Blue native/SDS gel electrophoresis of multi-protein complexes from whole cellular lysates: a proteomics approach

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389148

21 January 2018

Blue native polyacrylamide gel electrophoresis (BN-PAGE) for the identification and analysis of multiprotein complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389148

21 January 2018

Epithelial Na+ channel activation and processing in mice lacking SGK1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389148

21 January 2018

Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389148

21 January 2018

The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389148

21 January 2018

Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1

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https://pubmed.ncbi.nlm.nih.gov/22851176

12 December 2020

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Aldosterone-induced proteins in renal epithelia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851176

12 December 2020

based on heuristic

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Aldosterone-induced proteins: characterization using lectin-affinity chromatography

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https://pubmed.ncbi.nlm.nih.gov/22851176

12 December 2020

based on heuristic

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The epithelial sodium channel. Subunit number and location of the amiloride binding site

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https://pubmed.ncbi.nlm.nih.gov/22851176

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Associated proteins and renal epithelial Na+ channel function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851176

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NaPi-IIa interacting proteins and regulation of renal reabsorption of phosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851176

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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