Malic enzyme is present in mouse islets and modulates insulin secretion (Q28591279)

31 January 2017

title

Malic enzyme is present in mouse islets and modulates insulin secretion (English)

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Malic enzyme 1, NADP(+)-dependent, cytosolic

31 January 2017

main subject

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GOA release 2020-03-11

1 reference

J. Xu

1

1 reference

31 January 2017

J. Han

2

1 reference

31 January 2017

Y. S. Long

3

1 reference

31 January 2017

J. Lock

4

1 reference

31 January 2017

G. C. Weir

5

1 reference

31 January 2017

P. N. Epstein

6

1 reference

31 January 2017

Y. Q. Liu

7

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31 January 2017

language of work or name

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1 December 2008

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31 January 2017

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31 January 2017

volume

51

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31 January 2017

issue

12

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31 January 2017

page(s)

2281–2289

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Elimination of KATP channels in mouse islets results in elevated [U-13C]glucose metabolism, glutaminolysis, and pyruvate cycling but a decreased gamma-aminobutyric acid shunt

31 January 2017

cites work

1 reference

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A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion

17 March 2017

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Enhanced rat beta-cell proliferation in 60% pancreatectomized islets by increased glucose metabolic flux through pyruvate carboxylase pathway

17 March 2017

1 reference

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Cytosolic NADP(+)-dependent isocitrate dehydrogenase status modulates oxidative damage to cells

17 March 2017

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13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

17 March 2017

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A new mathematical model for relative quantification in real-time RT-PCR

17 March 2017

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NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion

17 March 2017

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Analysis of the putative role of 24‐carbon polyunsaturated fatty acids in the biosynthesis of docosapentaenoic (22:5n‐6) and docosahexaenoic (22:6n‐3) acids

17 March 2017

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Amino acid metabolism, insulin secretion and diabetes.

17 March 2017

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Dynamin is functionally coupled to insulin granule exocytosis

29 September 2017

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Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion

29 September 2017

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Glutamine regulates expression of key transcription factor, signal transduction, metabolic gene, and protein expression in a clonal pancreatic beta-cell line

29 September 2017

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A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion

29 September 2017

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Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion

29 September 2017

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Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion

29 September 2017

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The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose

29 September 2017

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13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells

29 September 2017

1 reference

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Beta-cell mitochondria and insulin secretion: messenger role of nucleotides and metabolites

29 September 2017

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Metabolic consequence of long-term exposure of pancreatic beta cells to free fatty acid with special reference to glucose insensitivity

29 September 2017

1 reference

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Activity of key enzymes in microsomal and mitochondrial membranes depends on the redox reactions involving lipid radicals.

29 September 2017

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Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

29 September 2017

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Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

29 September 2017

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Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

29 September 2017

1 reference

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Increased somatostatin content of islets from streptozotocin-diabetic rats

29 September 2017

1 reference

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Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose.

29 September 2017

1 reference

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Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin

3 June 2018

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Effect of adrenaline and phorbol myristate acetate or bacterial lipopolysaccharide on stimulation of pathways of macrophage glucose, glutamine and O2 metabolism. Evidence for cyclic AMP-dependent protein kinase mediated inhibition of glucose-6-phosp

3 June 2018

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Enzymes of glucose metabolism in normal mouse pancreatic islets

3 June 2018

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Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis

3 June 2018

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https://api.crossref.org/works/10.1007%2FS00125-008-1155-0

Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.

21 January 2018

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Chronic high glucose lowers pyruvate dehydrogenase activity in islets through enhanced production of long chain acyl-CoA: prevention of impaired glucose oxidation by enhanced pyruvate recycling through the malate-pyruvate shuttle

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777632

Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion

27 November 2018

1 reference

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beta-Cell adaptation to insulin resistance. Increased pyruvate carboxylase and malate-pyruvate shuttle activity in islets of nondiabetic Zucker fatty rats

27 November 2018

1 reference

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Critical role for cataplerosis via citrate in glucose-regulated insulin release

27 November 2018

1 reference

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Survey of normal appearing mouse strain which lacks malic enzyme and Nad+-linked glycerol phosphate dehydrogenase: normal pancreatic beta cell function, but abnormal metabolite pattern in skeletal muscle

27 November 2018

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Neuronal Death in Cultured Murine Cortical Cells Is Induced by Inhibition of GAPDH and Triosephosphate Isomerase

27 November 2018

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Isolation of thePichia pastoris PYC1 gene encoding pyruvate carboxylase and identification of a suppressor of thepyc phenotype

27 November 2018

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Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

27 November 2018

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Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets

27 November 2018

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12 December 2020

A simple, rapid, and sensitive DNA assay procedure

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12 December 2020

Identification and biochemical analysis of mouse mutants deficient in cytoplasmic malic enzyme

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12 December 2020

Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection

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12 December 2020

Pyruvate dehydrogenase and pyruvate carboxylase. Sites of pretranslational regulation by glucose of glucose-induced insulin release in pancreatic islets

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12 December 2020

NADPH: a stimulatory cofactor for nitric oxide-induced ADP-ribosylation reaction

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12 December 2020

Replication of adult pancreatic-beta cells cultured on bovine corneal endothelial cell extracellular matrix

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12 December 2020

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion

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12 December 2020

Quantifying the carboxylation of pyruvate in pancreatic islets

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12 December 2020

10.1007/S00125-008-1155-0

Identifiers

DOI

1 reference

Dimensions Publication ID

31 January 2017

1049753365

0 references

PMC publication ID

2777632

0 references

1 reference