p73 and p63 protein stability: the way to regulate function? (Q28590574)

31 January 2017

1 reference

Europe PubMed Central

title

p73 and p63 protein stability: the way to regulate function? (English)

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Transformation related protein 73

31 January 2017

main subject

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transformation related protein 63

GOA release 2020-03-11

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Small ubiquitin-like modifier 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00511-2

20 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00511-2

20 March 2024

1

Carine Maisse

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14555234

20 March 2024

author name string

Piero Guerrieri

2

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31 January 2017

Gerry Melino

3

1 reference

31 January 2017

language of work or name

English

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publication date

15 October 2003

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full work available at URL

31 January 2017

https://api.elsevier.com/content/article/PII:S0006295203005112?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00511-2

https://api.elsevier.com/content/article/PII:S0006295203005112?httpAccept=text/plain

20 March 2024

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00511-2

20 March 2024

published in

Biochemical Pharmacology

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31 January 2017

volume

66

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31 January 2017

issue

8

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31 January 2017

page(s)

1555–1561

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31 January 2017

cites work

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

On the shoulders of giants: p63, p73 and the rise of p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p73: Friend or foe in tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Role for the p53 homologue p73 in E2F-1-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Expression of DeltaNp73 is a molecular marker for adverse outcome in neuroblastoma patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p63 is a p53 homologue required for limb and epidermal morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Two new p73 splice variants, gamma and delta, with different transcriptional activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants ε and ζ

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Mdm2 promotes the rapid degradation of p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Mdm2 binds p73 alpha without targeting degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

MDM2 suppresses p73 function without promoting p73 degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Parc: a cytoplasmic anchor for p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p53 Stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Regulation of p73 by c-Abl through the p38 MAP kinase pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

Promoter specificity and stability control of the p53-related protein p73

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900511-2

p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein

7 January 2021

2

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00511-2

Subcellular distribution of p53 and p73 are differentially regulated by MDM2

20 March 2024

33

1 reference

https://api.crossref.org/works/10.1016/S0006-2952(03)00511-2

20 March 2024

Identifiers

0 references

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