Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice (Q28590362)

31 January 2017

title

Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice (English)

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31 January 2017

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arterial hypertension

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Bone morphogenetic protein receptor, type II (serine/threonine kinase)

inferred from title

endothelium

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GOA release 2020-03-11

pulmonary hypertension

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7

Joseph Loscalzo

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31 January 2017

Yanli Song

1

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31 January 2017

Laura Coleman

2

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31 January 2017

Jianru Shi

3

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31 January 2017

Hideyuki Beppu

4

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31 January 2017

Kaori Sato

5

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31 January 2017

Kenneth Walsh

6

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31 January 2017

Ying-Yi Zhang

8

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31 January 2017

publication date

1 August 2008

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American Journal of Physiology Heart and Circulatory Physiology

31 January 2017

published in

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31 January 2017

volume

295

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31 January 2017

issue

2

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31 January 2017

page(s)

H677–690

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Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Fractalkine in vascular biology: from basic research to clinical disease

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

BMP type II receptor is required for gastrulation and early development of mouse embryos

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

BMP signaling mediates stem/progenitor cell-induced retina regeneration

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Functional implication of BMP4 expression on angiogenesis in malignant melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Bone morphogenetic protein 4: potential regulator of shear stress-induced graft neointimal atrophy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

BMP-6 inhibits human bone marrow B lymphopoiesis--upregulation of Id1 and Id3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Blood island formation: longstanding observations and modern interpretations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

The role of Smad signaling in hematopoiesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Bone morphogenetic protein-2 stimulates angiogenesis in developing tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Controlling cell fate by bone morphogenetic protein receptors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Bone morphogenetic proteins stimulate angiogenesis through osteoblast-derived vascular endothelial growth factor A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Pulmonary hypertension and inflammation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

3 June 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Hypoxia and VEGF up-regulate BMP-2 mRNA and protein expression in microvascular endothelial cells: implications for fracture healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Dynamic changes in apoptotic and necrotic cell death correlate with severity of ischemia-reperfusion injury in lung transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Osteogenic protein-1, a bone morphogenetic protein, induces angiogenesis in the chick chorioallantoic membrane and synergizes with basic fibroblast growth factor and transforming growth factor-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Protective role of angiopoietin-1 in experimental pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2519229

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension

27 November 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.91519.2007

Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Stimulates an Inflammatory Response

21 January 2018

1 reference

12 December 2020

Arachidonic acid metabolites and the mechanisms of monocrotaline pneumotoxicity

1 reference

12 December 2020

Monocrotaline pneumotoxicity in mice

1 reference

12 December 2020

Chronic pulmonary hypertension--the monocrotaline model and involvement of the hemostatic system

1 reference

12 December 2020

Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development

1 reference

12 December 2020

Dysregulated Bone Morphogenetic Protein Signaling in Monocrotaline-Induced Pulmonary Arterial Hypertension

1 reference

12 December 2020

10.1152/AJPHEART.91519.2007

Identifiers

DOI

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31 January 2017

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