Regulation of T cell development by the deubiquitinating enzyme CYLD (Q28588773)

31 January 2017

title

Regulation of T cell development by the deubiquitinating enzyme CYLD (English)

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Lymphocyte protein tyrosine kinase

31 January 2017

main subject

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Zeta-chain (TCR) associated protein kinase

GOA release 2020-03-11

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CYLD lysine 63 deubiquitinase

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

William W. Reiley

1

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31 January 2017

Minying Zhang

2

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31 January 2017

Wei Jin

3

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31 January 2017

Mandy Losiewicz

4

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31 January 2017

Keri B. Donohue

5

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31 January 2017

Christopher C. Norbury

6

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31 January 2017

Shao-Cong Sun

7

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31 January 2017

language of work or name

English

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publication date

1 April 2006

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31 January 2017

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31 January 2017

volume

7

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31 January 2017

issue

4

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31 January 2017

page(s)

411–417

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T-cell development and the CD4-CD8 lineage decision

31 January 2017

cites work

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Positive and negative selection of T cells

21 January 2018

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Signalling in T-lymphocyte development: integration of signalling pathways is the key.

21 January 2018

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Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

21 January 2018

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Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

21 January 2018

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Signal transduction by the TCR for antigen

21 January 2018

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p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

21 January 2018

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Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex

21 January 2018

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SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction

21 January 2018

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Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck

21 January 2018

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Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors

21 January 2018

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Identification of the familial cylindromatosis tumour-suppressor gene

21 January 2018

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Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene

21 January 2018

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Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

21 January 2018

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The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

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CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

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Deubiquitinating enzymes as cellular regulators

21 January 2018

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Mechanism and function of deubiquitinating enzymes

21 January 2018

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The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor

21 January 2018

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Negative regulation of JNK signaling by the tumor suppressor CYLD.

21 January 2018

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The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7.

21 January 2018

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Lymphocyte populations and immune responses in CD5-deficient mice

21 January 2018

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Fine tuning of TCR signaling by CD5.

21 January 2018

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The role of erk1 and erk2 in multiple stages of T cell development

21 January 2018

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Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo.

21 January 2018

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Regulation of the Src family kinase Lck by Hsp90 and ubiquitination

21 January 2018

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Negative regulation of Lck by Cbl ubiquitin ligase

21 January 2018

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A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

21 January 2018

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Ubiquitin Lys63 is involved in ubiquitination of a yeast plasma membrane protein

21 January 2018

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TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

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Deubiquitinating enzymes: their roles in development, differentiation, and disease

21 January 2018

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Deubiquitinating enzymes: a new class of biological regulators

21 January 2018

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Deubiquitinating enzymes: their diversity and emerging roles

21 January 2018

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Ubiquitin ligases and the immune response

21 January 2018

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Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

21 January 2018

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Altered thymic positive selection and intracellular signals in Cbl-deficient mice

21 January 2018

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Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

21 January 2018

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Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

21 January 2018

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Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.

21 January 2018

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The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl

21 January 2018

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

21 January 2018

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cbl-b inhibits epidermal growth factor receptor signaling

21 January 2018

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Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha

21 January 2018

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NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase

21 January 2018

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Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages

21 January 2018

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NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

21 January 2018

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