Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells (Q28566691)

31 January 2017

title

Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells (English)

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31 January 2017

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6

Gordon C. Weir

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31 January 2017

Hideaki Kaneto

1

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31 January 2017

Kiyoshi Suzuma

2

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31 January 2017

Arun Sharma

3

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31 January 2017

Susan Bonner-Weir

4

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31 January 2017

George L. King

5

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31 January 2017

language of work or name

English

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publication date

1 February 2002

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

277

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31 January 2017

issue

5

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31 January 2017

page(s)

3680–3685

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Beta-cell adaptation and decompensation during the progression of diabetes.

31 January 2017

cites work

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Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations

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c-Myc target genes involved in cell growth, apoptosis, and metabolism

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Action of Myc in vivo - proliferation and apoptosis

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High glucose stimulates early response gene c-Myc expression in rat pancreatic beta cells

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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Protein kinase C activation and the development of diabetic complications

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Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation

21 January 2018

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Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats

21 January 2018

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Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation

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Targeted overexpression of protein kinase C β2 isoform in myocardium causes cardiomyopathy

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Localization of beta II subspecies of protein kinase C in beta-cells

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Immunocytochemical localization of alpha-protein kinase C in rat pancreatic beta-cells during glucose-induced insulin secretion

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A simplified system for generating recombinant adenoviruses

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The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter

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Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression

21 January 2018

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Oxidants, oxidative stress and the biology of ageing

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Role of oxidative stress in development of complications in diabetes

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Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

21 January 2018

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

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Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

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Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells.

21 January 2018

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Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress

21 January 2018

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

21 January 2018

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

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Activation of protein kinase C by tyrosine phosphorylation in response to H 2 O 2

21 January 2018

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The insulin gene contains multiple transcriptional elements that respond to glucose

21 January 2018

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The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells

21 January 2018

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Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells

21 January 2018

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Glucose-stimulated preproinsulin gene expression and nuclear trans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 MAPK/SAPK2.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M109647200

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Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017