Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems (Q28553478)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems	scientific article

Statements

scholarly article

0 references

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems (English)

0 references

infectious disease

0 references

Schistosoma mansoni

0 references

Alberto Bresciani

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Giovina Ruberti

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Edith Monteagudo

6

object named as

Edith Monteagudo

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Alessandra Guidi

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Cristiana Lalli

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Emerald Perlas

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Giulia Bolasco

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Martina Nibbio

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

0 references

publication date

August 2016

0 references

PLoS Neglected Tropical Diseases

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

e0004928

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

copyright license

Creative Commons Attribution 4.0 International

12 August 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

19 March 2017

Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

19 March 2017

Comparative study of transcriptome profiles of mechanical- and skin-transformed Schistosoma mansoni schistosomula

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

19 March 2017

Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

19 March 2017

Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

19 March 2017

Pharmacogenetics, drug-metabolizing enzymes, and clinical practice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

19 March 2017

Drug binding to human alpha-1-acid glycoprotein in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

19 March 2017

Use of 'dilute-and-shoot' liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Repurposing of anticancer drugs: in vitro and in vivo activities against Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

The metabolic control of schistosome egg production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Serum albumin and α-1 acid glycoprotein impede the killing of Schistosoma mansoni by the tyrosine kinase inhibitor Imatinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Gonad RNA-specific qRT-PCR analyses identify genes with potential functions in schistosome reproduction such as SmFz1 and SmFGFRs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Schistosomiasis control: praziquantel forever?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Disposition of mefloquine and enpiroline is highly influenced by a chronic Schistosoma mansoni infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Cell death and reproductive regression in female Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Something worth dyeing for: molecular tools for the dissection of lipid metabolism in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Schistosoma mansoni: signal transduction processes during the development of the reproductive organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Myocardial fatty acid metabolism in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Metabolic therapeutics in angina pectoris: history revisited with perhexiline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Reinfection with Schistosoma haematobium and mansoni despite repeated praziquantel office treatment in Niger, Mali

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Schistosome male-female interaction: induction of germ-cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Efficacy and safety of perhexiline maleate in refractory angina. A double-blind placebo-controlled clinical trial of a novel antianginal agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Properties of four acute phase proteins: C-reactive protein, serum amyloid A protein, alpha 1-acid glycoprotein, and fibrinogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Effects of phenformin and alpha-bromopalmitate on fatty acid and glucose oxidation in muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Schistosoma mansoni: a comparative study of artificially transformed schistosomula and schistomula recoverd after cercarial penetration of isolated skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

29 September 2017

Alpha1 acid glycoprotein binds to imatinib (STI571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

3 June 2018

Pharmacokinetics of the antianginal agent perhexiline: relationship between metabolic ratio and steady-state dose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

3 June 2018

Identification of 2-tetradecylglycidyl coenzyme A as the active form of methyl 2-tetradecylglycidate (methyl palmoxirate) and its characterization as an irreversible, active site-directed inhibitor of carnitine palmitoyltransferase A in isolated rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

3 June 2018

Reproductive development of female Schistosoma mansoni (Digenea: Schistosomatidae) following bisexual pairing of worms and worm segments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

3 June 2018

A comparative study of the reproductive system of mature, immature and "unisexual" female Schistosoma mansoni.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

3 June 2018

Pharmacologic profile of methyl 2-tetradecylglycidate (McN-3716)--an orally effective hypoglycemic agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

3 June 2018

Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Reinfection with Schistosoma haematobium following school-based chemotherapy with praziquantel in four highly endemic villages in Côte d'Ivoire

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Response of Schistosoma mansoni isolates having different drug sensitivity to praziquantel over several life cycle passages with and without therapeutic pressure

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Determination of ED50 values for praziquantel in praziquantel-resistant and -susceptible Schistosoma mansoni isolates

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Metabolic modulator perhexiline corrects energy deficiency and improves exercise capacity in symptomatic hypertrophic cardiomyopathy.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Drug-metabolizing enzymes and praziquantel bioavailability in mice harboring Schistosoma mansoni isolates of different drug susceptibilities.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

Presidential address. Sex and schistosomes: an interesting biological interplay with control implications

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0004928

21 January 2018

A perfusion technic for recovery of Schistosoma mansoni from experimentally infected guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4982595

27 November 2018

Intergeneric reproductive stimulation and parthenogenesis in Schistosoma mansoni

1 reference

https://pubmed.ncbi.nlm.nih.gov/27518281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Laboratory induced resistance to praziquantel in experimental schistosomiasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27518281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical Evaluation of Perhexiline Maleate in Patients with Angina Pectoris

1 reference

https://pubmed.ncbi.nlm.nih.gov/27518281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and pharmacokinetic study of praziquantel in Egyptian schistosomiasis patients with and without liver cell failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/27518281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Studies on resistance of Schistosoma to praziquantel XIII resistance of Schistosoma japonicum to praziquantel is experimentally induced in laboratory]

1 reference

https://pubmed.ncbi.nlm.nih.gov/27518281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schistosoma mansoni: a method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails

1 reference

https://pubmed.ncbi.nlm.nih.gov/27518281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of perhexiline and oxfenicine on myocardial function and metabolism during low-flow ischemia/reperfusion in the isolated rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/27518281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PNTD.0004928

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27518281%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28553478&oldid=1961677866"