BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation (Q28507269)

24 January 2017

title

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation (English)

1 reference

24 January 2017

1 reference

GOA release 2020-03-11

SMAD family member 1

1 reference

GOA release 2020-03-11

SMAD family member 5

1 reference

GOA release 2020-03-11

author name string

Kelsey N. Retting

1

1 reference

24 January 2017

Buer Song

2

1 reference

24 January 2017

Byeong S. Yoon

3

1 reference

24 January 2017

Karen M. Lyons

4

1 reference

24 January 2017

language of work or name

English

0 references

publication date

1 April 2009

1 reference

24 January 2017

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24 January 2017

volume

136

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24 January 2017

issue

7

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24 January 2017

page(s)

1093–1104

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Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis

24 January 2017

cites work

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Ucma--A novel secreted factor represents a highly specific marker for distal chondrocytes

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Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

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Sox9 is required for cartilage formation

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19 March 2017

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SOX9 directly regulates the type-II collagen gene

19 March 2017

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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

19 March 2017

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PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth

19 March 2017

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Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

19 March 2017

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SMAD proteins control DROSHA-mediated microRNA maturation

19 March 2017

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29 September 2017

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Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone

29 September 2017

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29 September 2017

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FGF signaling in the developing endochondral skeleton

29 September 2017

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29 September 2017

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29 September 2017

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Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype

29 September 2017

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29 September 2017

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Functions of transforming growth factor-beta family type I receptors and Smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes.

29 September 2017

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Smad-Runx interactions during chondrocyte maturation

29 September 2017

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A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia

29 September 2017

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Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development

29 September 2017

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Requirement of autocrine signaling by bone morphogenetic protein-4 for chondrogenic differentiation of ATDC5 cells

29 September 2017

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29 September 2017

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Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development

29 September 2017

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FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

29 September 2017

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29 September 2017

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The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation

29 September 2017

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SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

29 September 2017

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Parathyroid hormone/parathyroid hormone related peptide receptor gene transcripts are expressed from tissue-specific and ubiquitous promoters

29 September 2017

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29 September 2017

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Overexpression of FGFR3, Stat1, Stat5 and p21Cip1 correlates with phenotypic severity and defective chondrocyte differentiation in FGFR3-related chondrodysplasias

2 June 2018

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2 June 2018

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Development of the post-natal growth plate requires intraflagellar transport proteins

2 June 2018

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BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways.

27 November 2018

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Noggin antagonism of BMP4 signaling controls development of the axial skeleton in the mouse

27 November 2018

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Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification

27 November 2018

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Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling

27 November 2018

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Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.

27 November 2018

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Distinct functions of BMP4 and GDF5 in the regulation of chondrogenesis

27 November 2018

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Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes

27 November 2018

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p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation

27 November 2018

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Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse.

27 November 2018

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Role of collagen type II and perlecan in skeletal development.

27 November 2018

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Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation

27 November 2018

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Conditional knockout of the Smad1 gene.

27 November 2018

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STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation in mice overexpressing FGF2

27 November 2018

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Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice.

27 November 2018

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Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation.

27 November 2018

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Mice lacking link protein develop dwarfism and craniofacial abnormalities.

27 November 2018

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Medea is a Drosophila Smad4 homolog that is differentially required to potentiate DPP responses

27 November 2018

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Overexpression of BMP-2 and BMP-4 alters the size and shape of developing skeletal elements in the chick limb

27 November 2018

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Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

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12 December 2020

Initial characterization of PTH-related protein gene-driven lacZ expression in the mouse

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Smad4 is required for the normal organization of the cartilage growth plate

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Localization of Indian hedgehog and PTH/PTHrP receptor expression in relation to chondrocyte proliferation during mouse bone development

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12 December 2020

BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog

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12 December 2020

Activation of the ERK1/2 and p38 mitogen-activated protein kinase pathways mediates fibroblast growth factor-induced growth arrest of chondrocytes

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12 December 2020

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12 December 2020

PTHrP expression in chondrocytes, regulation by TGF-beta, and interactions between epiphyseal and growth plate chondrocytes

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12 December 2020