Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis (Q28506223)

24 January 2017

title

Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis (English)

1 reference

Activin A receptor, type 1B

24 January 2017

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GOA release 2020-03-11

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GOA release 2020-03-11

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1 reference

whole genome sequencing

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6

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author name string

Alexandre R. Colas

1

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24 January 2017

Wesley L. McKeithan

2

1 reference

24 January 2017

Thomas J. Cunningham

3

1 reference

24 January 2017

Paul J. Bushway

4

1 reference

24 January 2017

Lana X. Garmire

5

1 reference

24 January 2017

Shankar Subramaniam

7

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24 January 2017

Mark Mercola

8

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24 January 2017

publication date

1 December 2012

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24 January 2017

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24 January 2017

volume

26

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24 January 2017

issue

23

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24 January 2017

page(s)

2567–2579

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MicroRNAs: target recognition and regulatory functions

24 January 2017

cites work

1 reference

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The let-7 family of microRNAs

19 March 2017

1 reference

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Specific requirements of MRFs for the expression of muscle specific microRNAs, miR-1, miR-206 and miR-133

19 March 2017

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A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

19 March 2017

1 reference

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Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

19 March 2017

1 reference

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Selective blockade of microRNA processing by Lin28

19 March 2017

1 reference

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Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

19 March 2017

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Widespread microRNA repression by Myc contributes to tumorigenesis

19 March 2017

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Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

19 March 2017

1 reference

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Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevis

19 March 2017

1 reference

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The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Regulation of the let-7a-3 promoter by NF-κB.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Rapid differential transport of Nodal and Lefty on sulfated proteoglycan-rich extracellular matrix regulates left-right asymmetry inXenopus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The maternal-to-zygotic transition: a play in two acts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Nodal signaling: developmental roles and regulation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

High-throughput screening for modulators of stem cell differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Putting RNAs in the right place at the right time: RNA localization in the frog oocyte

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Morphogens, their identification and regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Ascorbic acid enhances differentiation of embryonic stem cells into cardiac myocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Morphogen gradients, positional information, and Xenopus: interplay of theory and experiment.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Dorsal gradient networks in the Drosophila embryo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Endodermal Nodal-related signals and mesoderm induction in Xenopus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

TheXenopus Brachyurypromoter is activated by FGF and low concentrations ofactivinandsuppressed by high concentrationsof activin and by paired-type homeodomain proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Conversion of zebrafish blastomeres to an endodermal fate by TGF-beta-related signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during earlyXenopusdevelopment but do not co-operate to establish thresholds

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The "organization centre". 3. Segregation and pattern formation in morphogenetic fields

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Xenopus laevis: Practical uses in cell and molecular biology. Solutions and protocols

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFB pathway in mouse palatal mesenchymal cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Micropatterning of human embryonic stem cells dissects the mesoderm and endoderm lineages

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Mix.1/2-dependent control of FGF availability during gastrulation is essential for pronephros development in Xenopus

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Patterning of mouse embryonic stem cell-derived pan-mesoderm by Activin A/Nodal and Bmp4 signaling requires Fibroblast Growth Factor activity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Developmental analysis of activin-like kinase receptor-4 (ALK4) expression in Xenopus laevis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Notch signaling can regulate endoderm formation in zebrafish.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Lefty-dependent inhibition of Nodal- and Wnt-responsive organizer gene expression is essential for normal gastrulation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Single cells can sense their position in a morphogen gradient

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Spatially distinct head and heart inducers within the Xenopus organizer region.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

Activin signalling and response to a morphogen gradient.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521625

nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation

27 November 2018

1 reference

12 December 2020

Xsox17alpha and -beta mediate endoderm formation in Xenopus

1 reference

12 December 2020

Fate map for the 32-cell stage of Xenopus laevis

1 reference

12 December 2020

Regulation of gut and heart left-right asymmetry by context-dependent interactions between xenopus lefty and BMP4 signaling

1 reference

12 December 2020

Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors

1 reference

12 December 2020

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1 reference

12 December 2020

Chapter 20 Assays for Gene Function in Developing Xenopus Embryos

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.200758.112

0 references

PMC publication ID

3521625

0 references

1 reference